English

Pixel multiplexing for high-speed multi-resolution fluorescence imaging

Quantitative Methods 2016-09-08 v1 Biological Physics Tissues and Organs

Abstract

We introduce a imaging modality that works by transiently masking image-subregions during a single exposure of a CCD frame. By offsetting subregion exposure time, temporal information is embedded within each stored frame, allowing simultaneous acquisition of a full high spatial resolution image and a high-speed image sequence without increasing bandwidth. The technique is demonstrated by imaging calcium transients in heart cells at 250 Hz with a 10 Hz megapixel camera.

Keywords

Cite

@article{arxiv.0910.0789,
  title  = {Pixel multiplexing for high-speed multi-resolution fluorescence imaging},
  author = {Gil Bub and Matthias Tecza and Michiel Helmes and Peter Lee and Peter Kohl},
  journal= {arXiv preprint arXiv:0910.0789},
  year   = {2016}
}

Comments

3 pages, 2 figures, submitted to Nature Methods

R2 v1 2026-06-21T13:54:15.493Z