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This paper proposes a Bayesian hierarchical model to characterize the relationship between birth weight and maternal pre-eclampsia across gestation at a large maternity hospital in urban Uganda. Key scientific questions we investigate…

Child mortality is an important population health indicator. However, many countries lack high-quality vital registration to measure child mortality rates precisely and reliably over time. Research endeavors such as those by the United…

Applications · Statistics 2026-01-29 Katherine R Paulson , Taylor Okonek , Jon Wakefield

Estimating prevalence, the fraction of a population with a certain medical condition, is fundamental to epidemiology. Traditional methods rely on classification of test samples taken at random from a population. Such approaches to…

Methodology · Statistics 2022-03-25 Paul Patrone , Anthony Kearsley

Expectation Propagation (EP) is a widely used message-passing algorithm that decomposes a global inference problem into multiple local ones. It approximates marginal distributions (beliefs) using intermediate functions (messages). While…

Information Theory · Computer Science 2026-01-30 Zilu Zhao , Fangqing Xiao , Dirk Slock

Invariant prediction [Peters et al., 2016] analyzes feature/outcome data from multiple environments to identify invariant features - those with a stable predictive relationship to the outcome. Such features support generalization to new…

Machine Learning · Statistics 2025-07-10 Luhuan Wu , Mingzhang Yin , Yixin Wang , John P. Cunningham , David M. Blei

Estimates of the under-five mortality rate (U5MR) are used to track progress in reducing child mortality and to evaluate countries' performance related to Millennium Development Goal 4. However, for the great majority of developing…

Applications · Statistics 2015-01-20 Leontine Alkema , Jin Rou New

While the HVTN 505 trial showed no overall efficacy of the tested vaccine to prevent HIV infection over placebo, previous studies, biological theories, and the finding that immune response markers strongly correlated with infection in…

Applications · Statistics 2018-11-12 Peter B. Gilbert , Bryan S. Blette , Bryan E. Shepherd , Michael G. Hudgens

Within epidemiological modeling, the majority of analyses assume a single epidemic process for generating ground-truth data. However, this assumed data generation process can be unrealistic, since data sources for epidemics are often…

Artificial Intelligence · Computer Science 2021-06-22 Anna L. Trella , Peniel N. Argaw , Michelle M. Li , James A. Hay

Background: Approximately 40% of adults in Botswana are HIV-infected. The Botswana antiretroviral program began in 2002 and currently treats 34,000 patients with a goal of treating 85,000 patients (~30% of HIV-infected adults) by 2009. We…

Populations and Evolution · Quantitative Biology 2007-05-23 Raffaele Vardavas , Sally Blower

It is the main purpose of this paper to introduce a graph-valued stochastic process in order to model the spread of a communicable infectious disease. The major novelty of the SIR model we promote lies in the fact that the social network on…

Applications · Statistics 2014-02-06 Charanpal Dhanjal , Stéphan Clémençon

The prediction interval has been increasingly used in meta-analyses as a useful measure for assessing the magnitude of treatment effect and between-studies heterogeneity. In calculations of the prediction interval, although the…

Methodology · Statistics 2021-07-14 Yuta Hamaguchi , Hisashi Noma , Kengo Nagashima , Tomohide Yamada , Toshi A. Furukawa

Effective intervention strategies for epidemics rely on the identification of their origin and on the robustness of the predictions made by network disease models. We introduce a Bayesian uncertainty quantification framework to infer model…

Populations and Evolution · Quantitative Biology 2020-04-02 Karen Larson , Clark Bowman , Zhizhong Chen , Panagiotis Hadjidoukas , Costas Papadimitriou , Petros Koumoutsakos , Anastasios Matzavinos

Clinical decision-making demands uncertainty quantification that provides both distribution-free coverage guarantees and risk-adaptive precision, requirements that existing methods fail to jointly satisfy. We present a hybrid…

Machine Learning · Computer Science 2026-01-06 Marzieh Amiri Shahbazi , Ali Baheri , Nasibeh Azadeh-Fard

Acute infectious diseases are transmitted over networks of social contacts. Epidemic models are used to predict the spread of emergent pathogens and compare intervention strategies. Many of these models assume equal probability of contact…

Applications · Statistics 2016-11-25 Gail E. Potter , Niel Hens

This paper presents an impact assessment for the imputation of missing data. The data set used is HIV Seroprevalence data from an antenatal clinic study survey performed in 2001. Data imputation is performed through five methods: Random…

Methodology · Statistics 2020-11-25 Adam Pantanowitz , Tshilidzi Marwala

It is difficult to accurately estimate the rates of rape and domestic violence due to the sensitive nature of these crimes. There is evidence that bias in estimating the crime rates from survey data may arise because some women respondents…

Methodology · Statistics 2008-07-28 Qingzhao Yu , Elizabeth A. Stasny , Bin Li

Frequently, empirical studies are plagued with missing data. When the data are missing not at random, the parameter of interest is not identifiable in general. Without additional assumptions, we can derive bounds of the parameters of…

Methodology · Statistics 2018-09-12 Zhichao Jiang , Peng Ding

The objective is to model longitudinal and survival data jointly taking into account the dependence between the two responses in a real HIV/AIDS dataset using a shared parameter approach inside a Bayesian framework. We propose a linear…

Applications · Statistics 2016-05-02 Rui Martins

This study investigates an inverse problem associated with a time-fractional HIV infection model incorporating nonlinear diffusion. The model describes the dynamics of uninfected target cells, infected cells, and free virus particles, where…

Numerical Analysis · Mathematics 2025-04-01 Mohamed BenSalah , Salih Tatar , Suleyman Ulusoy

We investigate Bayesian predictive inference for finite population quantities when there are unequal probabilities of selection. Only limited information about the sample design is available; i.e., only the first-order selection…

Methodology · Statistics 2018-04-10 Junheng Ma , Joe Sedransk , Balgobin Nandram , Lu Chen