Homotopy versus isotopy: spheres with duals in 4-manifolds

David Gabai recently proved a smooth 4-dimensional "Light Bulb Theorem" in the absence of 2-torsion in the fundamental group. We extend his result to 4-manifolds with arbitrary fundamental group by showing that an invariant of Mike Freedman and Frank Quinn gives the complete obstruction to "homotopy implies isotopy" for embedded 2-spheres which have a common geometric dual. The invariant takes values in an Z/2Z-vector space generated by elements of order 2 in the fundamental group and has applications to unknotting numbers and pseudo-isotopy classes of self-diffeomorphisms. Our methods also give an alternative approach to Gabai's theorem using various maneuvers with Whitney disks and a fundamental isotopy between surgeries along dual circles in an orientable surface.