English

Guided Neuronal Growth on Arrays of Biofunctionalized GaAs/InGaAs Semiconductor Microtubes

Soft Condensed Matter 2015-06-15 v1 Materials Science Biological Physics

Abstract

We demonstrate embedded growth of cortical mouse neurons in dense arrays of semiconductor microtubes. The microtubes, fabricated from a strained GaAs/InGaAs heterostructure, guide axon growth through them and enable electrical and optical probing of propagating action potentials. The coaxial nature of the microtubes -- similar to myelin -- is expected to enhance the signal transduction along the axon. We present a technique of suppressing arsenic toxicity and prove the success of this technique by overgrowing neuronal mouse cells.

Keywords

Cite

@article{arxiv.1305.1218,
  title  = {Guided Neuronal Growth on Arrays of Biofunctionalized GaAs/InGaAs Semiconductor Microtubes},
  author = {Cornelius S. Bausch and Aune Koitmäe and Eric Stava and Amanda Price and Pedro J. Resto and Yu Huang and David Sonnenberg and Yuliya Stark and Christian Heyn and Justin C. Williams and Erik W. Dent and Robert H. Blick},
  journal= {arXiv preprint arXiv:1305.1218},
  year   = {2015}
}

Comments

3 pages, 4 figures