English

Boundedness and asymptotic stability in a model for tuberculosis granuloma formation

Analysis of PDEs 2026-03-06 v2

Abstract

This paper deals with a problem which describes tuberculosis granuloma formation \begin{align*} \begin{cases} u_t = \Delta u - \nabla \cdot (u \nabla v) - uv - u + \beta, &x \in \Omega,\ t>0, \\ v_t = \Delta v + v -uv + \mu w, &x \in \Omega,\ t>0, \\ w_t = \Delta w + uv - wz - w, &x \in \Omega,\ t>0, \\ z_t = \Delta z - \nabla \cdot (z \nabla w) + f(w)z -z, &x \in \Omega,\ t>0 \end{cases} \end{align*} under homogeneous Neumann boundary conditions and initial conditions, where ΩRn\Omega \subset \mathbb{R}^n (n2n\ge 2) is a smooth bounded domain, β,μ>0\beta,\mu>0 and ff is some function, and shows that if initial data are small in some sense then the solution (u,v,w,z)(u,v,w,z) of the problem exists globally and convergences to (β,0,0,0)(\beta,0,0,0) exponentially when β>1\beta>1 and the reproduction number R0:=μβ+1βR_0 := \frac{\mu \beta + 1}{\beta} satisfies R0<1R_0<1.

Keywords

Cite

@article{arxiv.2506.16752,
  title  = {Boundedness and asymptotic stability in a model for tuberculosis granuloma formation},
  author = {Masaaki Mizukami and Yuya Tanaka},
  journal= {arXiv preprint arXiv:2506.16752},
  year   = {2026}
}