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Boundedness enforced by mildly saturated conversion in a chemotaxis-May-Nowak model for virus infection

Analysis of PDEs 2018-12-14 v1

Abstract

We study the system \begin{align*} \label{prob:star} \tag{\star} \begin{cases} u_t = \Delta u - \nabla \cdot (u \nabla v) - u - f(u) w + \kappa, \\ v_t = \Delta v - v + f(u) w, \\ w_t = \Delta w - w + v, \end{cases} \end{align*} which models the virus dynamics in an early stage of an HIV infection, in a smooth, bounded domain ΩRn,nN,\Omega \subset \mathbb R^n, n \in \mathbb N, for a parameter κ0\kappa \ge 0 and a given function fC1([0,))f \in C^1([0, \infty)) satisfying f0f \ge 0, f(0)=0f(0) = 0 and f(s)Kfsαf(s) \le K_f s^\alpha for all s1s \ge 1, some Kf>0K_f \gt 0 and αR\alpha \in \mathbb R. We prove that whenever \begin{align*} \alpha \lt \frac2n, \end{align*} solutions to \eqref{prob:star} exist globally and are bounded. The proof mainly relies on smoothing estimates for the Neumann heat semigroup and (in the case α>1\alpha \gt 1) on a functional inequality. Furthermore, we provide some indication why the exponent 2n\frac2n could be essentially optimal.

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Cite

@article{arxiv.1809.10960,
  title  = {Boundedness enforced by mildly saturated conversion in a chemotaxis-May-Nowak model for virus infection},
  author = {Mario Fuest},
  journal= {arXiv preprint arXiv:1809.10960},
  year   = {2018}
}

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12 pages