English

Dampening effect of logistic source in a two-dimensional haptotaxis system with nonlinear zero-order interaction

Analysis of PDEs 2020-05-21 v1

Abstract

This paper deals with the oncolytic virotherapy model \begin{equation}\begin{split} \begin{cases} &u_t = \Delta u - \nabla \cdot (u\nabla v)-uz +\mu u(1-u),& \\[2ex] &v_t = - (u+w)v,& \\[2ex] &w_t = D_w \Delta w - w + uz,& \\[2ex] &z_t = D_z \Delta z - z - uz + \beta w,& \end{cases} \end{split}\end{equation} in a bounded domain Ω\Omega \subset R2\Bbb{R}^2 with smooth boundary, where μ\mu, DwD_w, DzD_z and β\beta are prescribed positive parameters. For any given suitably regular initial data, the global existence of classical solution to the corresponding homogeneous Neumann initial-boundary problem for a more general model allowing μ=0\mu=0 was previously verified in [[Y. Tao &\& M. Winkler, J. Differential Equations 268\mathbf{268} (2020), 4973-4997]]. This work further shows that whenever μ>0\mu>0, the above-mentioned global classical solution to the above equation is uniformly bounded; and moreover, if β<1\beta<1, then the solution (u,v,w,z)(u, v, w, z) stabilizes to the constant equilibrium (1,0,0,0)(1, 0, 0, 0) in the topology Lp(Ω)×(L(Ω))3L^p(\Omega)\times (L^\infty(\Omega))^3 with any p>1p>1 in a large time limit.

Keywords

Cite

@article{arxiv.2005.09915,
  title  = {Dampening effect of logistic source in a two-dimensional haptotaxis system with nonlinear zero-order interaction},
  author = {Chen Zhen},
  journal= {arXiv preprint arXiv:2005.09915},
  year   = {2020}
}

Comments

16 pages

R2 v1 2026-06-23T15:40:51.910Z