相关论文: Microtubules: The neuronic system of the neurons?

Short-term memory in the brain cannot in general be explained the way long-term memory can -- as a gradual modification of synaptic weights -- since it takes place too quickly. Theories based on some form of cellular bistability, however,…

Although conditional branching between possible behavioural states is a hallmark of intelligent behavior, very little is known about the neuronal mechanisms that support this processing. In a step toward solving this problem we demonstrate…

Microtubules self-organize to form part of the cellular cytoskeleton. They give cells their shape and play a crucial role in cell division and intracellular transport. Strikingly, microtubules driven by motor proteins reorganize into stable…

Deep convolutional neural networks (CNNs) have structures that are loosely related to that of the primate visual cortex. Surprisingly, when these networks are trained for object classification, the activity of their early, intermediate, and…

Understanding how subjective experience arises from information processing remains a central challenge in neuroscience, cognitive science, and AI research. The Modular Consciousness Theory (MCT) proposes a biologically grounded and…

Motivated by the potential similarities between the underlying mechanisms of the enhanced memory storage capacity in black holes and in brain networks, we construct an artificial quantum neural network based on gravity-like synaptic…

The neural networks of the human brain act as very efficient parallel processing computers co-ordinating memory related responses to a multitude of input signals from sensory organs. Information storage, update and appropriate retrieval are…

We present a coarse-grained two dimensional mechanical model for the microtubule-tau bundles in neuronal axons in which we remove taus, as can happen in various neurodegenerative conditions such as Alzheimer's disease, tauopathies, and…

When the human brain manifests the birth of organised communication among local and large-scale neuronal populations activity remains undescribed. We report, in resting-state EEG source-estimates of 100 infants at term age, the existence of…

The non-perturbative dynamics of quantum field theories is studied using theoretical tools inspired by string formalism. Two main lines are developed: the analysis of stringy instantons in a class of four-dimensional N=2 gauge theories and…

Subthreshold oscillations in neurons are those oscillations which do not attain the critical value of the membrane's voltage needed for triggering an action potential (a spike). Their contribution to the forming of action potentials in…

Temporal Neural Networks (TNNs) are spiking neural networks that use time as a resource to represent and process information, similar to the mammalian neocortex. In contrast to compute-intensive deep neural networks that employ separate…

Neurons, as eukaryotic cells, have powerful internal computation capabilities. One neuron can have many distinct states, and brains can use this capability. Processes of neuron growth and maintenance use chemical signalling between cell…

Running deep neural networks on microcontroller units (MCUs) is severely constrained by limited memory resources. While TinyML techniques reduce model size and computation, they often fail in practice due to excessive peak Random Access…

In this study, a two-state mechanochemical model is presented to describe the dynamic instability of microtubules (MTs) in cells. The MTs switches between two states, assembly state and disassembly state. In assembly state, the growth of…

Cognitive function is driven by dynamic interactions between large-scale neural circuits or networks, enabling behavior. Fundamental principles constraining these dynamic network processes have remained elusive. Here we use network control…

The ability of discrete-time nonlinear recurrent neural networks to store time-varying small input signals is investigated by mean-field theory. The combination of a small input strength and mean-field assumptions makes it possible to…

Spiking Neural Networks (SNNs) have incorporated more biologically-plausible structures and learning principles, hence are playing critical roles in bridging the gap between artificial and natural neural networks. The spikes are the sparse…

Criticality can be exactly demonstrated in certain models of brain activity, yet it remains challenging to identify in empirical data. We trained a fully connected deep neural network to learn the phases of an excitable model unfolding on…

At functional scales, cortical behavior results from the complex interplay of a large number of excitable cells operating in noisy environments. Such systems resist to mathematical analysis, and computational neurosciences have largely…