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Statistical properties of environments experienced by biological signaling systems in the real world change, which necessitate adaptive responses to achieve high fidelity information transmission. One form of such adaptive response is gain…

分子网络 · 定量生物学 2012-05-01 Ilya Nemenman

The implications of large-scale coherence in biological systems and possible links to quantum theory are only beginning to be explored. Whether quantum-like coherent phenomena are relevant, or even possible at all, at the high temperatures…

其他定量生物学 · 定量生物学 2012-12-04 Martin Robert

The paper firstly argues from conservation principles that, when dealing with physics aside from elementary particle interactions, the number of naturally independent quantities, and hence the minimum number of base quantities within a unit…

综合物理 · 物理学 2020-01-08 Paul Quincey , Kathryn Burrows

Proteins are the essential drivers of biological processes. At the molecular level, they are chains of amino acids that can be viewed through a linguistic lens where the twenty standard residues serve as an alphabet combining to form a…

In the context of evolutionary quantum computing in the literal meaning, a quantum crossover operation has not been introduced so far. Here, we introduce a novel quantum genetic algorithm which has a quantum crossover procedure performing…

神经与进化计算 · 计算机科学 2014-02-05 Akira SaiToh , Robabeh Rahimi , Mikio Nakahara

Generating molecules, both in a directed and undirected fashion, is a huge part of the drug discovery pipeline. Genetic algorithms (GAs) generate molecules by randomly modifying known molecules. In this paper we show that GAs are very…

神经与进化计算 · 计算机科学 2023-10-16 Austin Tripp , José Miguel Hernández-Lobato

Physics and computer science have a long tradition of cross-fertilization. One of the latest outcomes of this mutually beneficial relationship is quantum information science, which comprises the study of information processing tasks that…

量子物理 · 物理学 2020-06-17 Fei Yan , Salvador E. Venegas-Andraca , Kaoru Hirota

Understanding of how biological neural networks process information is one of the biggest open scientific questions of our time. Advances in machine learning and artificial neural networks have enabled the modeling of neuronal behavior, but…

量子物理 · 物理学 2024-09-17 Vinicius Hernandes , Eliska Greplova

Biological systems, from cells to organisms, must respond to the ever changing environment in order to survive and function. This is not a simple task given the often random nature of the signals they receive, as well as the intrinsically…

定量方法 · 定量生物学 2015-07-09 Aleksandra M. Walczak

In living systems, we often see the emergence of the ingredients necessary for computation -- the capacity for information transmission, storage, and modification -- begging the question of how we may exploit or imitate such biological…

神经元与认知 · 定量生物学 2020-09-11 Kristine Heiney , Gunnar Tufte , Stefano Nichele

Quantum computers process information with the laws of quantum mechanics. Current quantum hardware is noisy, can only store information for a short time, and is limited to a few quantum bits, i.e., qubits, typically arranged in a planar…

We live in a world brimming with uncertainty, where we constantly have to make a lot of decisions under incomplete information. We are firm believers that our subjective belief cannot be computed by rigorous mathematical formula; instead…

物理与社会 · 物理学 2023-02-08 Lizhi Xin , Kevin Xin , Houwen Xin

The future development of quantum technologies relies on creating and manipulating quantum systems of increasing complexity, with key applications in computation, simulation and sensing. This poses severe challenges in the efficient…

Genetic information is encoded in a linear sequence of nucleotides, represented by letters ranging from thousands to billions. Mutations refer to changes in the DNA or RNA nucleotide sequence. Thus, mutation detection is vital in all areas…

By considering the energy cost of messages carried by proteins as proportional to their information content we found experimental proof that proteins from all living organisms tend to have their estimated semantic content of information per…

生物大分子 · 定量生物学 2007-05-23 Robersy Sanchez , Ricardo Grau

The training of molecular models of quantum mechanical properties based on statistical machine learning requires large datasets which exemplify the map from chemical structure to molecular property. Intelligent a priori selection of…

Inside every living cell is the cytoplasm: a fluid mixture of thousands of different macromolecules, predominantly proteins. This mixture is where most of the biochemistry occurs that enables living cells to function, and it is perhaps the…

软凝聚态物质 · 物理学 2009-11-11 Richard P. Sear

Life has a special status, it even has its own science: biology. In many ways, the logic of life seems to differ from that of atoms, molecules, planets, or any other `inanimate object'. However, life is increasingly measured using…

其他定量生物学 · 定量生物学 2021-12-16 Marc-Antoine Fardin

Quantum mechanics---the theory describing the fundamental workings of nature---is famously counterintuitive: it predicts that a particle can be in two places at the same time, and that two remote particles can be inextricably and…

Life is characterized by a myriad of complex dynamic processes allowing organisms to grow, reproduce, and evolve. Physical approaches for describing systems out of thermodynamic equilibrium have been increasingly applied to living systems,…

生物物理 · 物理学 2020-12-16 Xiaona Fang , Karsten Kruse , Ting Lu , Jin Wang