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To model biological systems using networks, it is desirable to allow more than two levels of expression for the nodes and to allow the introduction of parameters. Various modeling and simulation methods addressing these needs using Boolean…

分子网络 · 定量生物学 2014-04-23 Yi Ming Zou

Dynamic transportation networks have been analyzed for years by means of static graph-based indicators in order to study the temporal evolution of relevant network components, and to reveal complex dependencies that would not be easily…

机器学习 · 统计学 2022-02-25 Hector Rodriguez-Deniz , Mattias Villani , Augusto Voltes-Dorta

Prediction of molecular properties, including physico-chemical properties, is a challenging task in chemistry. Herein we present a new state-of-the-art multitask prediction method based on existing graph neural network models. We have used…

机器学习 · 计算机科学 2019-10-31 Fabio Capela , Vincent Nouchi , Ruud Van Deursen , Igor V. Tetko , Guillaume Godin

Here we introduce probabilistic weighted and unweighted multilayer networks as derived from information theoretical correlation measures on large multidimensional datasets. We present the fundamentals of the formal application of…

Statistical analysis on networks has received growing attention due to demand from various emerging applications. In dynamic networks, one of the key interests is to model the event history of time-stamped interactions amongst nodes. We…

统计方法学 · 统计学 2018-10-09 Tony Sit , Zhiliang Ying , Yi Yu

The mathematical models used to capture features of complex, biological systems are typically non-linear, meaning that there are no generally valid simple relationships between their outputs and the data that might be used to validate them.…

定量方法 · 定量生物学 2014-04-23 Thomas House

Complex networks, modeled as large graphs, received much attention during these last years. However, data on such networks is only available through intricate measurement procedures. Until recently, most studies assumed that these…

网络与互联网体系结构 · 计算机科学 2007-05-23 Matthieu Latapy , Clemence Magnien

We study the statistical properties of the sampled scale-free networks, deeply related to the proper identification of various real-world networks. We exploit three methods of sampling and investigate the topological properties such as…

无序系统与神经网络 · 物理学 2009-11-24 Sang Hoon Lee , Pan-Jun Kim , Hawoong Jeong

Investigating the frequency and distribution of small subgraphs with a few nodes/edges, i.e., motifs, is an effective analysis method for static networks. Motif-driven analysis is also useful for temporal networks where the spectrum of…

社会与信息网络 · 计算机科学 2021-05-04 Penghang Liu , Valerio Guarrasi , A. Erdem Sarıyüce

Random Boolean networks have been used widely to explore aspects of gene regulatory networks. A modified form of the model through which to systematically explore the effects of increasing the number of gene states has previously been…

分子网络 · 定量生物学 2023-02-06 Larry Bull

The processes taking place inside the living cell are now understood to the point where predictive computational models can be used to gain detailed understanding of important biological phenomena. A key challenge is to extrapolate this…

组织与器官 · 定量生物学 2018-10-26 Stefan Engblom Daniel B. Wilson , Ruth E. Baker

Recently, evolving networks are becoming a suitable form to model many real-world complex systems, due to their peculiarities to represent the systems and their constituting entities, the interactions between the entities and the…

人工智能 · 计算机科学 2017-09-21 Angelo Impedovo , Corrado Loglisci , Michelangelo Ceci

Bayesian networks are a versatile and powerful tool to model complex phenomena and the interplay of their components in a probabilistically principled way. Moving beyond the comparatively simple case of completely observed, static data,…

统计方法学 · 统计学 2020-11-04 Marco Scutari

Although asymptotic analyses of undirected network models based on degree sequences have started to appear in recent literature, it remains an open problem to study statistical properties of directed network models. In this paper, we…

统计理论 · 数学 2016-01-13 Ting Yan , Chenlei Leng , Ji Zhu

This paper studies reduced-order modeling of dynamic networks with strongly connected topology. Given a graph clustering of an original complex network, we construct a quotient graph with less number of vertices, where the edge weights are…

最优化与控制 · 数学 2020-03-10 Xiaodong Cheng , Lanlin Yu , Dingchao Ren , Jacquelien M. A. Scherpen

Probabilistic Graphical Models are often used to understand dynamics of a system. They can model relationships between features (nodes) and the underlying distribution. Theoretically these models can represent very complex dependency…

机器学习 · 计算机科学 2023-08-21 Harsh Shrivastava , Urszula Chajewska

We derive properties of Latent Variable Models for networks, a broad class of models that includes the widely-used Latent Position Models. These include the average degree distribution, clustering coefficient, average path length and degree…

统计方法学 · 统计学 2015-06-26 Riccardo Rastelli , Nial Friel , Adrian E. Raftery

The past decade has seen a revived interest in the unavoidable or intrinsic noise in biochemical and genetic networks arising from the finite copy number of the participating species. That is, rather than modeling regulatory networks in…

分子网络 · 定量生物学 2015-03-17 Aleksandra M. Walczak , Andrew Mugler , Chris H. WIggins

Understanding the mathematical properties of graphs underling biological systems could give hints on the evolutionary mechanisms behind these structures. In this article we perform a complete statistical analysis over thousands of graphs…

分子网络 · 定量生物学 2019-08-29 D. Gamermann , J. Triana , R. Jaime

A dynamic logic method was developed to analyze molecular networks of cells by combining Kauffman and Thomas's logic operations with molecular interaction parameters. The logic operations characterize the discrete interactions between…

定量方法 · 定量生物学 2008-06-11 Suping Lyu
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