相关论文: Topological coding in hippocampus

Topological data analyses are rapidly turning into key tools for quantifying large volumes of neurobiological data, e.g., for organizing the spiking outputs of large neuronal ensembles and thus gaining insights into the information produced…

Hippocampal cognitive map---a neuronal representation of the spatial environment---is broadly discussed in the computational neuroscience literature for decades. More recent studies point out that hippocampus plays a major role in producing…

Spatial awareness in mammals is based on internalized representations of the environment---cognitive maps---encoded by networks of spiking neurons. Although behavioral studies suggest that these maps can remain stable for long periods, it…

Topological techniques have become a popular tool for studying information flows in neural networks. In particular, simplicial homology theory is used to analyze how cognitive representations of space emerge from large conglomerates of…

Spatial navigation in mammals is based on building a mental representation of their environment---a cognitive map. However, both the nature of this cognitive map and its underpinning in neural structures and activity remains vague. A key…

Mammalian hippocampus plays a key role in spatial learning and memory, but the exact nature of the hippocampal representation of space is still being explored. Recently, there has been a fair amount of success in modeling hippocampal…

It is widely accepted that the hippocampal place cells' spiking activity produces a cognitive map of space. However, many details of this representation's physiological mechanism remain unknown. For example, it is believed that the place…

We discuss the task of reconstructing the topological map of an environment based on the sequences of locations visited by a mobile agent -- this occurs in systems neuroscience, where one runs into the task of reconstructing the global…

In present paper we discuss several approaches to reconstructing the topology of the physical space from neural activity data of CA1 fields in mice hippocampus, in particular, having Cognitome theory of brain function in mind. In our…

A common approach to interpreting spiking activity is based on identifying the firing fields---regions in physical or configuration spaces that elicit responses of neurons. Common examples include hippocampal place cells that fire at…

The spiking activity of the hippocampal place cells plays a key role in producing and sustaining an internalized representation of the ambient space---a cognitive map. These cells do not only exhibit location-specific spiking during…

Various neurophysiological and cognitive functions are based on transferring information between spiking neurons via a complex system of synaptic connections. In particular, the capacity of presynaptic inputs to influence the postsynaptic…

We develop of a line of work initiated by Curto and Itskov towards understanding the amount of information contained in the spike trains of hippocampal place cells via topology considerations. Previously, it was established that simply…

The mammalian hippocampus plays a principal role in producing a cognitive map of space---an internalized representation of the animal's environment. The neuronal mechanisms producing this map depend primarily on the temporal structure of…

High-dimensional neural activity often reside in a low-dimensional subspace, referred to as neural manifolds. Grid cells in the medial entorhinal cortex provide a periodic spatial code that are organized near a toroidal manifold,…

The spiking activity of principal cells in mammalian hippocampus encodes an internalized neuronal representation of the ambient space---a cognitive map. Once learned, such a map enables the animal to navigate a given environment for a long…

Neurons in the brain are spatially organized such that neighbors on tissue often exhibit similar response profiles. In the human language system, experimental studies have observed clusters for syntactic and semantic categories, but the…

The hippocampal formation is thought to learn spatial maps of environments, and in many models this learning process consists of forming a sensory association for each location in the environment. This is inefficient, akin to learning a…

Place cells in the rat hippocampus play a key role in creating the animal's internal representation of the world. During active navigation, these cells spike only in discrete locations, together encoding a map of the environment.…

Discussions of the hippocampus often focus on place cells, but many neurons are not place cells in any given environment. Here we describe the collective activity in such mixed populations, treating place and non-place cells on the same…