相关论文: Topological coding in hippocampus
Codifying memories is one of the fundamental problems of modern Neuroscience. The functional mechanisms behind this phenomenon remain largely unknown. Experimental evidence suggests that some of the memory functions are performed by…
The standard model of memory consolidation foresees that memories are initially recorded in the hippocampus, while features that capture higher-level generalisations of data are created in the cortex, where they are stored for a possibly…
Neural computation is associated with the emergence, reconfiguration and dissolution of cell assemblies in the context of varying oscillatory states. Here, we describe the complex spatio-temporal dynamics of cell assemblies through temporal…
Can neural networks learn goal-directed behaviour using similar strategies to the brain, by combining the relationships between the current state of the organism and the consequences of future actions? Recent work has shown that recurrent…
While cognitive representations of an environment can last for days and even months, the synaptic architecture of the neuronal networks that underlie these representations constantly changes due to various forms of synaptic and structural…
The hippocampus supports spatial navigation by encoding cognitive maps through collective place cell activity. We model the place cell population as non-negative spatial embeddings derived from the spectral decomposition of multi-step…
It is now widely accepted that one of the roles of the hippocampus is to maintain episodic spatial representations, while parallel striatal pathways contribute to both declarative and procedural value computations by encoding different…
This thesis is a compendium of research which brings together ideas from the fields of Complex Networks and Computational Neuroscience to address two questions regarding neural systems: 1) How the activity of neurons, via synaptic changes,…
The vertebrate hippocampus is believed to use recurrent connectivity in area CA3 to support episodic memory recall from partial cues. This brain area also contains place cells, whose location-selective firing fields implement maps…
Brain decoding involves the determination of a subject's cognitive state or an associated stimulus from functional neuroimaging data measuring brain activity. In this setting the cognitive state is typically characterized by an element of a…
As a vital cognitive function of animals, the navigation skill is first built on the accurate perception of the directional heading in the environment. Head direction cells (HDCs), found in the limbic system of animals, are proven to play…
Hippocampal place cells can encode spatial locations of an animal in physical or task-relevant spaces. We simulated place cell populations that encoded either Euclidean- or graph-based positions of a rat navigating to goal nodes in a maze…
The brain achieves stability and plasticity in a topologically complex, shifting world through Metric-Topology Factorization (MTF), separating discrete topological indexing for context selection from continuous metric condensation for local…
A variety of behaviors like spatial navigation or bodily motion can be formulated as graph traversal problems through cognitive maps. We present a neural network model which can solve such tasks and is compatible with a broad range of…
The hippocampus and the striatum support episodic and procedural memory, respectively, and "place" and "response" learning within spatial navigation. Recently this dichotomy has been linked to "model-based" and "model-free" reinforcement…
The brain's spatial orientation system uses different neuron ensembles to aid in environment-based navigation. Two of the ways brains encode spatial information is through head direction cells and grid cells. Brains use head direction cells…
This paper presents a highly speculative model encompassing the cortex, thalamus, and hippocampus of the mammalian brain. While the majority of computational neuroscience models are founded upon empirical evidence, this model is predicated…
The dynamics of a neural model for hippocampal place cells storing spatial maps is studied. In the absence of external input, depending on the number of cells and on the values of control parameters (number of environments stored, level of…
In the mammalian brain newly acquired memories depend on the hippocampus for maintenance and recall, but over time these functions are taken over by the neocortex through a process called systems consolidation. However, reactivation of a…
Functional networks provide a topological description of activity patterns in the brain, as they stem from the propagation of neural activity on the underlying anatomical or structural network of synaptic connections. This latter is well…