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A method was developed for Bayesian inference of species phylogeny using the multi-species coalescent model. To improve the mixing properties of the Markov chain Monte Carlo (MCMC) algorithm that traverses the space of species trees, we…

种群与进化 · 定量生物学 2015-12-15 Bruce Rannala , Ziheng Yang

Objective: Spike sorting is a fundamental step in analysing extracellular recordings, enabling the isolation of single-neuron activity. However, it remains a challenging problem because extracellular traces mix overlapping spikes from…

信号处理 · 电气工程与系统科学 2025-06-12 Vasileios Georgiadis , Panagiotis C. Petrantonakis

One step in the conventional analysis of extracellularly recorded neuronal data is spike sorting, which separates electrical signal into action potentials from different neurons. Because spike sorting involves human judgment, it can be…

神经元与认知 · 定量生物学 2007-05-23 Artur Luczak , Nandakumar S. Narayanan

We propose a construction for joint feature learning and clustering of multichannel extracellular electrophysiological data across multiple recording periods for action potential detection and discrimination ("spike sorting"). Our…

We address the problem of finding patterns from multi-neuronal spike trains that give us insights into the multi-neuronal codes used in the brain and help us design better brain computer interfaces. We focus on the synchronous firings of…

神经与进化计算 · 计算机科学 2010-06-09 Raajay Viswanathan , P. S. Sastry , K. P. Unnikrishnan

Nowadays we witness a miniaturisation trend in the semiconductor industry backed up by groundbreaking discoveries and designs in nanoscale characterisation and fabrication. To facilitate the trend and produce ever smaller, faster and…

神经与进化计算 · 计算机科学 2021-03-30 Karolos-Alexandros Tsakalos , Georgios Ch. Sirakoulis , Andrew Adamatzky , Jim Smith

In spiking neural networks (SNNs), the main unit of information processing is the neuron with an internal state. The internal state generates an output spike based on its component associated with the membrane potential. This spike is then…

机器学习 · 计算机科学 2025-08-11 Sanja Karilanova , Subhrakanti Dey , Ayça Özçelikkale

Much of studies on neural computation are based on network models of static neurons that produce analog output, despite the fact that information processing in the brain is predominantly carried out by dynamic neurons that produce discrete…

神经元与认知 · 定量生物学 2017-06-21 Dongsung Huh , Terrence J. Sejnowski

The Markov Chain Monte Carlo (MCMC) algorithm is a widely recognised as an efficient method for sampling a specified posterior distribution. However, when the posterior is multi-modal, conventional MCMC algorithms either tend to become…

天体物理仪器与方法 · 物理学 2014-08-19 Yi-Ming Hu , Martin Hendry , Ik Siong Heng

Spike-based neuromorphic hardware promises to reduce the energy consumption of image classification and other deep learning applications, particularly on mobile phones or other edge devices. However, direct training of deep spiking neural…

神经与进化计算 · 计算机科学 2021-01-27 Christoph Stöckl , Wolfgang Maass

Spike sorting algorithms are used to separate extracellular recordings of neuronal populations into single-unit spike activities. The development of customized hardware implementing spike sorting algorithms is burgeoning. However, there is…

机器学习 · 计算机科学 2025-01-30 Tim Zhang , Corey Lammie , Mostafa Rahimi Azghadi , Amirali Amirsoleimani , Majid Ahmadi , Roman Genov

Developing electrophysiological recordings of brain neuronal activity and their analysis provide a basis for exploring the structure of brain function and nervous system investigation. The recorded signals are typically a combination of…

神经元与认知 · 定量生物学 2019-11-01 Sahar Hojjatinia , Constantino M. Lagoa

Spike sorting refers to the problem of assigning action potentials observed in extra-cellular recordings of neural activity to the neuron(s) from which they originate. We cast this problem as one of learning a convolutional dictionary from…

统计方法学 · 统计学 2018-06-07 Andrew H. Song , Francisco Flores , Demba Ba

This paper deals with the problem of extracting the activity of individual neurons from multi-electrode recordings. Important aspects of this work are: 1) the sorting is done in two stages - a statistical model of the spikes from different…

数据分析、统计与概率 · 物理学 2007-05-23 Dima Rinberg , William Bialek , Hanan Davidowitz , Naftali Tishby

Monte Carlo approaches have recently been proposed to quantify connectivity in neuronal networks. The key problem is to sample from the conditional distribution of a single neuronal spike train, given the activity of the other neurons in…

应用统计 · 统计学 2011-12-01 Yuriy Mishchenko , Liam Paninski

Inspired by the mammal's auditory localization pathway, in this paper we propose a pure spiking neural network (SNN) based computational model for precise sound localization in the noisy real-world environment, and implement this algorithm…

音频与语音处理 · 电气工程与系统科学 2020-07-08 Zihan Pan , Malu Zhang , Jibin Wu , Haizhou Li

A fundamental problem in neuroscience is to characterize the dynamics of spiking from the neurons in a circuit that is involved in learning about a stimulus or a contingency. A key limitation of current methods to analyze neural spiking…

统计方法学 · 统计学 2017-09-29 Yingzhuo Zhang , Noa Malem-Shinitski , Stephen A Allsop , Kay Tye , Demba Ba

Sparse sequences of neural spikes are posited to underlie aspects of working memory, motor production, and learning. Discovering these sequences in an unsupervised manner is a longstanding problem in statistical neuroscience. Promising…

机器学习 · 统计学 2020-10-13 Alex H. Williams , Anthony Degleris , Yixin Wang , Scott W. Linderman

Background: Current neuronal monitoring techniques, such as calcium imaging and multi-electrode arrays, enable recordings of spiking activity from hundreds of neurons simultaneously. Of primary importance in systems neuroscience is the…

神经元与认知 · 定量生物学 2014-11-11 Yazan N. Billeh , Michael T. Schaub , Costas A. Anastassiou , Mauricio Barahona , Christof Koch

Spiking Neural Networks (SNNs) hold great potential to realize brain-inspired, energy-efficient computational systems. However, current SNNs still fall short in terms of multi-scale temporal processing compared to their biological…

神经与进化计算 · 计算机科学 2024-08-28 Xinyi Chen , Jibin Wu , Chenxiang Ma , Yinsong Yan , Yujie Wu , Kay Chen Tan