相关论文: Vaccination pattern affects immunological response

We examine here the effects of recurrent vaccination and waning immunity on the establishment of an endemic equilibrium in a population. An individual-based model that incorporates memory effects for transmission rate during infection and…

We study how a fraction of a population should be vaccinated to most efficiently top epidemics. We argue that only local information (about the neighborhood of specific vertices) is usable in practice, and hence we consider only local…

We model the immune surveillance of a pathogen which passes through $n$ immunologically distinct stages. The biological parameters of this system induce a partial order on the stages, and this, in turn, determines which stages will be…

Inspired by Minority Games, we constructed a novel individual-level game of adaptive decision-making based on the dilemma of deciding whether to participate in voluntary influenza vaccination programs. The proportion of the population…

Vaccination campaigns have both direct and indirect effects that act to control an infectious disease as it spreads through a population. Indirect effects arise when vaccinated individuals block disease transmission in any infection chains…

In this study, we present an immuno-epidemic model to understand mitigation options during an epidemic break. The model incorporates comorbidity and multiple-vaccine doses through a system of coupled integro-differential equations to…

Incorporating vaccination into mathematical models appears deceptively simple: models integrate vaccine-derived protections, such as reduced susceptibility to infection, using parameters informed by empirical estimates of vaccine efficacy…

It is proposed that using both self-non-self and danger theories give a better understanding of how the immune system works. It is proposed that comparing immune system to police force is useful in this case since police responds both to…

One of the most important tools available to limit the spread and impact of infectious diseases is vaccination. It is therefore important to understand what factors determine people's vaccination decisions. To this end, previous behavioural…

Laboratory models are often used to understand the interaction of related pathogens via host immunity. For example, recent experiments where ferrets were exposed to two influenza strains within a short period of time have shown how the…

We study how the interplay between the memory immune response and pathogen mutation affects epidemic dynamics in two related models. The first explicitly models pathogen mutation and individual memory immune responses, with contacted…

In diseases with long-term immunity, vaccination is known to increase the average age at infection as a result of the decrease in the pathogen circulation. This implies that a vaccination campaign can have negative effects when a disease is…

Variations in individuals' perceptions of vaccination and decision-making processes can give rise to poor vaccination coverage. The future vaccination promotion programs will benefit from understanding this heterogeneity amongst groups…

Voluntary vaccination is effective to prevent infectious diseases from spreading. Both vaccination behavior and cognition of the vaccination risk play important roles in individual vaccination decision making. However, it is not clear how…

We consider the interplay of vaccination and migration rates on disease persistence in epidemiological systems. We show that short-term and long-term migration can inhibit disease persistence. As a result, we show how migration changes how…

The rapid outbreak of bird flu challenges the outcome of effective vaccine for the upcoming years. The recent research established different norms to eliminate flu pandemics. This can be made possible with skilled experimental analyses and…

In this paper, we study the optimal control for an SEIR model adapted to the vaccination strategy of susceptible individuals. There are factors associated with a vaccination campaign that make this strategy not only a public health issue…

This study aims to statistically assess the effectiveness of vaccination against SARS-CoV-2. It is indispensable to investigate the relationship between Covid-19 deadliness and vaccination in order to study the impact of vaccine in…

Waning immunity and reinfection are critical features of many infectious diseases, but epidemiological models often fail to capture the intricate interaction between an individual's history of immunity and their current infection status;…

We propose a new method to immunize populations or computer networks against epidemics which is more efficient than any method considered before. The novelty of our method resides in the way of determining the immunization targets. First we…