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相关论文: Modularity "for free" in genome architecture?

200 篇论文

We propose a growing network model that consists of two tunable mechanisms: growth by merging modules which are represented as complete graphs and a fitness-driven preferential attachment. Our model exhibits the three prominent statistical…

分子网络 · 定量生物学 2007-07-31 Kazuhiro Takemoto , Chikoo Oosawa

Scale-free networks are abundant in nature and society, describing such diverse systems as the world wide web, the web of human sexual contacts, or the chemical network of a cell. All models used to generate a scale-free topology are…

统计力学 · 物理学 2009-11-07 Albert-Laszlo Barabasi , Erzsebet Ravasz , Tamas Vicsek

Metabolic networks are known to be scale free but the evolutionary origin of this structural property is not clearly understood. One way of studying the dynamical process is to compare the metabolic networks of species that have arisen at…

分子网络 · 定量生物学 2007-05-23 Shalini , Areejit Samal , Varun Giri , Sandeep Krishna , N. Raghuram , Sanjay Jain

The functional consequences of local and global dynamics can be very different in natural systems. Many such systems have a network description that exhibits strong local clustering as well as high communication efficiency, often termed as…

生物物理 · 物理学 2009-04-07 Raj Kumar Pan , Sitabhra Sinha

We investigate the selective forces that promote the emergence of modularity in nature. We demonstrate the spontaneous emergence of modularity in a population of individuals that evolve in a changing environment. We show that the level of…

种群与进化 · 定量生物学 2009-11-13 Jun Sun , Michael W. Deem

Living organisms produce metabolites of many types via their metabolisms. Especially, flavonoids, a kind of secondary metabolites, of plant species are interesting examples. Since plant species are believed to have specific flavonoids with…

种群与进化 · 定量生物学 2015-03-19 Kazuhiro Takemoto

We review the recent fast progress in statistical physics of evolving networks. Interest has focused mainly on the structural properties of random complex networks in communications, biology, social sciences and economics. A number of giant…

统计力学 · 物理学 2015-06-24 S. N. Dorogovtsev , J. F. F. Mendes

In this paper, we propose an evolving network model growing fast in units of module, based on the analysis of the evolution characteristics in real complex networks. Each module is a small-world network containing several interconnected…

物理与社会 · 物理学 2011-10-11 Zou Zhi-Yun , Liu Peng , Lei Li , Gao Jian-Zhi

A large computer program is typically divided into many hundreds or even thousands of smaller units, whose logical connections define a network in a natural way. This network reflects the internal structure of the program, and defines the…

无序系统与神经网络 · 物理学 2009-11-10 Alessandro P. S. de Moura , Ying-Cheng Lai , Adilson E. Motter

Various real-life networks of current interest are simultaneously scale-free and modular. Here we study analytically the average distance in a class of deterministically growing scale-free modular networks. By virtue of the recursive…

物理与社会 · 物理学 2010-12-09 Zhongzhi Zhang , Yuan Lin , Shuigeng Zhou , Zhigang Wang , Jihong Guan

The next step in the understanding of the genome organization, after the determination of complete sequences, involves proteomics. The proteome includes the whole set of protein-protein interactions, and two recent independent studies have…

统计力学 · 物理学 2007-05-23 Ricard V. Sole , Romualdo Pastor-Satorras , Eric Smith , Thomas B. Kepler

Several networks occurring in real life have modular structures that are arranged in an hierarchical fashion. In this paper, we have proposed a model for such networks, using a stochastic generation method. Using this model we show that,…

物理与社会 · 物理学 2009-03-12 Raj Kumar Pan , Sitabhra Sinha

Complex dynamical systems are often modeled as networks, with nodes representing dynamical units which interact through the network's links. Gene regulatory networks, responsible for the production of proteins inside a cell, are an example…

统计力学 · 物理学 2009-09-30 Zoran Levnajić

In this paper we introduce a model of spatial network growth in which nodes are placed at randomly selected locations on a unit square in $\mathbb{R}^2$, forming new connections to old nodes subject to the constraint that edges do not…

物理与社会 · 物理学 2016-02-12 Garvin Haslett , Seth Bullock , Markus Brede

What is the underlying mechanism leading to power-law degree distributions of many natural and artificial networks is still at issue. We consider that scale-free networks emerges from self-organizing process, and such a evolving model is…

统计力学 · 物理学 2007-05-23 Gang Yan , Tao Zhou , Ying-Di Jin , Zhong-Qian Fu

A central biological question is how natural organisms are so evolvable (capable of quickly adapting to new environments). A key driver of evolvability is the widespread modularity of biological networks--their organization as functional,…

种群与进化 · 定量生物学 2015-03-13 Jeff Clune , Jean-Baptiste Mouret , Hod Lipson

Scale-free networks are ubiquitous in social, biological and technological networked systems. Dynamic Scale-free networks and their synchronizations are important to understand and predict the behavior of social, biological and…

社会与信息网络 · 计算机科学 2024-09-16 Rakib Hassan Pran

Hierarchical organization -- the recursive composition of sub-modules -- is ubiquitous in biological networks, including neural, metabolic, ecological, and genetic regulatory networks, and in human-made systems, such as large organizations…

神经与进化计算 · 计算机科学 2016-09-28 Henok Mengistu , Joost Huizinga , Jean-Baptiste Mouret , Jeff Clune

A common trait of complex systems is that they can be represented by means of a network of interacting parts. It is, in fact, the network organisation (more than the parts) what largely conditions most higher-level properties, which are not…

种群与进化 · 定量生物学 2019-07-15 Ricard Sole , Sergi Valverde

The architecture of biological networks has been reported to exhibit high level of modularity, and to some extent, topological modules of networks overlap with known functional modules. However, how the modular topology of the molecular…

分子网络 · 定量生物学 2007-09-07 Jing Zhao , Guo-Hui Ding , Lin Tao , Hong Yu , Zhong-Hao Yu , Jian-Hua Luo , Zhi-Wei Cao , Yi-Xue Li