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Collective behavior of proteins on biomembranes is usually studied within the spontaneous curvature model. Here we consider an alternative phenomenological approach, which accounts consistently for partial ordering of proteins as well as…

软凝聚态物质 · 物理学 2014-09-03 O. V. Manyuhina

We present a novel Monte Carlo simulation of the phase separation dynamics of a model fluid membrane. Such a phase segregation induces shape changes of the membrane and results in local `budding' under favourable conditions. We present a…

凝聚态物理 · 物理学 2007-05-23 P. B. Sunil Kumar , Madan Rao

Ever since the raft model for biomembranes has been proposed, the traditional view of biomembranes based on the fluid-mosaic model has been altered. In the raft model, dynamical heterogeneities in multi-component lipid bilayers play an…

软凝聚态物质 · 物理学 2014-10-16 Shigeyuki Komura , David Andelman

Osmotic deflation of vesicles enclosing two liquid phases can lead to bulging of one of the phases from the vesicle body. This budding process is preceded by a complete to partial wetting transition of one of the liquid phases on the…

软凝聚态物质 · 物理学 2012-01-17 Yanhong Li , Halim Kusumaatmaja , Reinhard Lipowsky , Rumiana Dimova

We adopt the point of view that analysis of the stability of the protein folding process is central to understanding the underlying physics of folding. Stability of the folding process means that many perturbations do not disrupt the…

生物物理 · 物理学 2011-12-30 Walter Simmons , Joel L. Weiner

The motion of flexible fibers through structured fluidic environments is ubiquitous in nature and industrial applications. Most often, their dynamics results from the complex interplay between internal elastic stresses, contact forces and…

流体动力学 · 物理学 2022-09-23 Ursy Makanga , Mohammadreza Sepahi , Camille Duprat , Blaise Delmotte

Biological membranes are host to proteins and molecules which may form domain-like structures resulting in spatially-varying material properties. Vesicles with such heterogeneous membranes can exhibit intricate shapes at equilibrium and…

软凝聚态物质 · 物理学 2023-06-22 Prerna Gera , David Salac , Saverio E. Spagnolie

According to the lipid raft hypothesis, biological lipid membranes are laterally heterogeneous and filled with nanoscale ordered "raft" domains, which are believed to play an important role for the organization of proteins in membranes.…

生物物理 · 物理学 2013-03-22 Sebastian Meinhardt , Richard L. C. Vink , Friederike Schmid

Space-filling assemblies of athermal hydrophobic particles floating at an air-water interface, called particle rafts, are shown to undergo an unusual phase transition between two i.e., a low density `less-rigid and a high density…

无序系统与神经网络 · 物理学 2015-06-11 Atul Varshney , A. Sane , Shankar Ghosh , S. Bhattacharya

Rafts, or functional domains, are transient nano- or mesoscopic structures in the plasma membrane and are thought to be essential for many cellular processes such as signal transduction, adhesion, trafficking and lipid/protein sorting.…

The emergence of hydrodynamic bend instabilities in ordered suspensions of active particles is widely observed across diverse living and synthetic systems, and is considered to be governed by dipolar active stresses generated by the…

软凝聚态物质 · 物理学 2026-01-09 Sameer Kumar , Niels de Graaf Sousa , Amin Doostmohammadi

We study the effect of membrane proteins on the shape, composition and thermodynamic stability of the surrounding membrane. When the coupling between membrane composition and curvature is strong enough the nearby composition and shape both…

软凝聚态物质 · 物理学 2015-03-11 S. Alex Rautu , George Rowlands , Matthew S. Turner

The complex physics of self-assembly in colloidal crystals on deformable interfaces and surfaces poses interesting possibilities for the designability and synthesis of next-generation metamaterials. The goal of this article is to…

软凝聚态物质 · 物理学 2025-06-23 Sanjay Dharmavaram , Basant Lal Sharma

We study theoretically the shapes of biological tubes affected by various pathologies. When epithelial cells grow at an uncontrolled rate, the negative tension produced by their division provokes a buckling instability. Several shapes are…

生物物理 · 物理学 2012-07-09 Edouard Hannezo , Jean-Francois Joanny , Jacques Prost

The formation of microdomains, also called rafts, in biomembranes can be attributed to the surface tension of the membrane. In order to model this phenomenon, a model involving a coupling between the local composition and the local…

偏微分方程分析 · 数学 2016-06-29 Irene Fonseca , Gurgen Hayrapetyan , Giovanni Leoni , Barbara Zwicknagl

Induced by proteins within the cell membrane or by differential growth, heating, or swelling, spontaneous curvatures can drastically affect the morphology of thin bodies and induce mechanical instabilities. Yet, the interaction of…

软凝聚态物质 · 物理学 2018-01-31 Matteo Pezzulla , Norbert Stoop , Mark P. Steranka , Abdikhalaq J. Bade , Douglas P. Holmes

The mechanism of hydrodynamics-induced pairing of soft particles, namely closed bilayer membranes (vesicles, a model system for red blood cells) and drops, is studied numerically with a special attention paid to the role of the confinement…

Complex evolving systems such as the biosphere, ecosystems and societies exhibit sudden collapses, for reasons that are only partially understood. Here we study this phenomenon using a mathematical model of a system that evolves under…

适应与自组织系统 · 物理学 2007-05-23 Ravi Mehrotra , Vikram Soni , Sanjay Jain

In experiments on model membranes, a formation of large domains of different lipid composition is readily observed. However, no such phase separation is observed in the membranes of intact cells. Instead, a structure of small transient…

软凝聚态物质 · 物理学 2017-08-23 Timo Fischer , H. Jelger Risselada , Richard L. C. Vink

Membrane budding has been extensively studied as an equilibrium process attributed to the formation of coexisting domains or changes in the vesicle area to volume ratio (reduced volume). In contrast, non-equilibrium budding remains…

生物物理 · 物理学 2013-03-27 Thomas Franke , Christian T. Leirer , Achim Wixforth , Nily Dan , Matthias F. Schneider
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