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As inkjet technology develops to produce smaller droplets, substrate features such as accidental scratches or manufacturing defects can potentially affect the outcome of printing, particularly for printed electronics where continuous tracks…

流体动力学 · 物理学 2021-09-15 Khaled H. A. Al-Ghaithi , Oliver G. Harlen , Nikil Kapur , Mark C. T. Wilson

We have developed a method for producing spatially stable micron-scale liquid targets of flexible shapes at kilohertz repetition rate for use in air and vacuum, by perturbing 5 and 30 \mu m diameter streams with femtosecond laser pulses and…

流体动力学 · 物理学 2012-12-17 Pavel Chvykov , Wise Ongg , James Easter , Bixue Hou , John Nees , Karl Krushelnick

We present a high-throughput microfluidic platform capable of quantitating up to 384 biomarkers in 4 distinct samples by immunoassay. The microfluidic device contains 384 unit cells, which can be individually programmed with pairs of…

定量方法 · 定量生物学 2015-06-23 Francesca Volpetti , Jose Garcia-Cordero , Sebastian Maerkl

Micromanipulations, perfusions and measurements performed using glass microelectrodes filled with an electrolyte is a conventional technique for experimental morphological and membrane electrophysiological studies at a single cell and…

亚细胞过程 · 定量生物学 2018-07-27 O. V. Gradov , P. A. Nasirov , A. A. Scrynnic , A. G. Jablokov

In this paper, we report a capillary-based M-Z interferometer that could be used for precise detection of variations in refractive indices of gaseous samples. This sensing mechanism is quite straightforward. Cladding and core modes of a…

应用物理 · 物理学 2020-03-10 Haijin Chen , Xuehao Hu , Meifan He , Pengfei Ren , Chao Zhang , Hang Qu

Droplet microfluidics offers a versatile platform for analyzing liquid samples. Despite its potential, there is a lack of techniques that allow to reliably probe individual circulating droplets. The prospect of combining droplet…

定量方法 · 定量生物学 2024-03-08 Marc Sulliger , Jaime Ortega Arroyo , Romain Quidant

A nanoparticle detection scheme with single particle resolution is presented. The sensor contains only a taper fiber thus offering the advantages of compactness and installation flexibility. Sensing method is based on monitoring the…

光学 · 物理学 2013-05-31 Jiangang Zhu , Sahin Kaya Ozdemir , Lan Yang

We present a 3D-printing-based design to produce wire-guided liquid microfilms that can be used for versatile spectroscopic applications. We demonstrate the ability of our instrument to provide optically useful liquid microfilms with highly…

化学物理 · 物理学 2025-07-04 Matthew J. Silverstein , Yasashri Ranathunga , Yuki Kobayashi

We demonstrate a compact piezoelectric-driven micropipette launcher for localized in-vacuum delivery of nano- and microparticles into optical traps. The launcher has been integrated into multiple optical trapping setups, including a…

Fast-responding detector arrays are commonly used for imaging rapidly-changing scenes. Besides array detectors, a single-pixel detector combined with a broadband optical spectrum can also be used for rapid imaging by mapping the spectrum…

光学 · 物理学 2019-09-04 Chengying Bao , Myoung-Gyun Suh , Kerry Vahala

Microfluidic droplet screens serve as an innovative platform for high-throughput biotechnology, enabling significant advancements in discovery, product optimization, and analysis. This review sheds light on the emerging trend of interaction…

定量方法 · 定量生物学 2023-09-11 Carolus Vitalis , Tobias Wenzel

In situ polymerization and micropatterning of hydrogels on-chip opens the potential for many applications such as tracking and controlling the diffusion of molecules, stimulants, inhibitors, as well as nutrients and drugs, from their source…

Purpose: We introduce a novel concept of a compact multiprobe scintillator detector and demonstrate its applicability in HDR-brachytherapy. Our fabricated seven-probe system is sufficiently narrow to be inserted in a brachytherapy needle or…

Suspensions of micro and nano particles made of Polystyrene, Poly(methyl methacrylate), Silicon dioxide etc. have been a standard model system to understand colloidal physics. . These systems have proved useful insights into phenomena such…

软凝聚态物质 · 物理学 2017-10-04 Praneet Prakash , Manoj Varma

A mini-PET style detector system is being developed for a plant imaging application with a compact array of silicon photomultipliers (SiPM) replacing position sensitive photomultipliers (PSPMT). In addition to compactness, the use of SiPMs…

Although printed transistors have a wide range of applications, the limited resolution of printing techniques (10-30 um) has been a barrier to advancement and scaling, particularly down to submicron dimensions. While previous works have…

A major public health issue is the growing resistance of bacteria to antibiotics. An important part of the needed response is the discovery and development of new antimicrobial strategies. These require the screening of potential new drugs,…

应用统计 · 统计学 2026-02-19 Byran Smucker , Benjamin Brennan , Emily Rego , Meng Wu , Zhihong Lin , Brian Ahmer , Blake Peterson

Gravimetry typically lacks the resolution to measure single microdroplets, whereas microscopy is often inaccurate beyond the resolution limit. To address these issues, we advance and integrate these complementary methods, introducing…

In this work we present an active Compton scattering polarimeter as a focal plane instrument able to extend the X-ray polarimetry towards hard X-rays. Other authors have already studied various instrument design by means of Monte Carlo…

天体物理仪器与方法 · 物理学 2013-01-08 Sergio Fabiani , Riccardo Campana , Enrico Costa , Ettore Del Monte , Fabio Muleri , Alda Rubini , Paolo Soffitta

The occurrence of multiple strains of a bacterial pathogen such as M. tuberculosis or C. difficile within a single human host, referred to as a mixed infection, has important implications for both healthcare and public health. However,…