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Models invoking the chemical master equation are used in many areas of science, and, hence, their simulation is of interest to many researchers. The complexity of the problems at hand often requires considerable computational power, so a…

生物物理 · 物理学 2016-03-02 Fabian Spill , Philip K. Maini , Helen Byrne

Global optimization heuristics are popular to optimize hard non-convex problems. Despite their irrefutably large cost-to-solution, in the lack of other working greedy or convex approaches, global optimization algorithms remain the…

最优化与控制 · 数学 2025-02-24 Kayo Gonçalves-e-Silva , Samuel Xavier-de-Souza

In this article we present an algorithm to efficiently evaluate the exchange matrix in periodic systems when Gaussian basis set with pseudopotentials are used. The usual algorithm for evaluating exchange matrix scales cubically with the…

强关联电子 · 物理学 2022-11-11 Sandeep Sharma , Alec F. White , Gregory Beylkin

In this article, we provide an alternative up-sampling and PSF deconvolution method for the iterative multi-exposure coaddition. Different from the previous works, the new method has a ratio-correction term, which allows the iterations to…

天体物理仪器与方法 · 物理学 2022-10-26 Lei Wang , Guoliang Li , Xi Kang

For simulation studies of (macro) molecular liquids it would be of significant interest to be able to adjust or increase the level of resolution within one region of space, while allowing for the free exchange of molecules between open…

The random phase approximation (RPA) systematically overestimates the magnitude of the correlation energy and generally underestimates cohesive energies. This originates in part from the complete lack of exchange terms, which would…

材料科学 · 物理学 2018-12-12 Felix Hummel , Andreas Grüneis , Georg Kresse , Paul Ziesche

Fast frame-rates are desirable in scanning transmission electron microscopy for a number of reasons: controlling electron beam dose, capturing in-situ events or reducing the appearance of scan distortions. Whilst several strategies exist…

仪器与探测器 · 物理学 2023-08-09 Jonathan J. P Peters , Tiarnan Mullarkey , James A. Gott , Elizabeth Nelson , Lewys Jones

We discuss multi-dimensional generalizations of multicanonical algorithm, simulated tempering, and replica-exchange method. We generalize the original potential energy function $E_0$ by adding any physical quantity $V$ of interest as a new…

统计力学 · 物理学 2008-10-08 Ayori Mitsutake , Yuko Okamoto

In engineering, it is a common desire to couple existing simulation tools together into one big system by passing information from subsystems as parameters into the subsystems under influence. As executed at fixed time points, this data…

数值分析 · 数学 2017-04-25 Thilo Moshagen

Recently, we introduced Relative Resolution as a hybrid formalism for fluid mixtures [1]. The essence of this approach is that it switches molecular resolution in terms or relative separation: While nearest neighbors are characterized by a…

统计力学 · 物理学 2019-10-09 Aviel Chaimovich , Kurt Kremer , Christine Peter

In this work a replica exchange Monte Carlo scheme which considers an extended isobaric-isothermal ensemble with respect to pressure is applied to study hard spheres (HS). The idea behind the proposal is expanding volume instead of…

统计力学 · 物理学 2015-05-20 Gerardo Odriozola

We propose a new generalized-ensemble algorithm, which we refer to as the multicanonical-multioverlap algorithm. By utilizing a non-Boltzmann weight factor, this method realizes a random walk in the multi-dimensional, energy-overlap space…

统计力学 · 物理学 2009-11-11 Satoru G. Itoh , Yuko Okamoto

We test the effectiveness of the multicanonical algorithm for the tertiary structure prediction of peptides and proteins. As a simple example we study Met-enkephalin. The lowest-energy conformation obtained agrees with that determined by…

凝聚态物理 · 物理学 2007-05-23 Ulrich H. E. Hansmann , Yuko Okamoto

A recent reformulation [1] of the problem of Coulomb gases in the presence of a dynamical dielectric medium showed that finite temperature simulations of such systems can be accomplished on the basis of completely local Hamiltonians on a…

软凝聚态物质 · 物理学 2009-11-11 A. Duncan , R. D. Sedgewick

Complex soft matter systems can be efficiently studied with the help of adaptive resolution simulation methods, concurrently employing two levels of resolution in different regions of the simulation domain. The non-matching properties of…

Replica exchange (REX) is one of the most widely used enhanced sampling methodologies, yet its efficiency is limited by the requirement for a large number of intermediate temperature replicas. Here we present Generative Replica Exchange…

生物大分子 · 定量生物学 2026-03-20 Shengjie Huang , Sijie Yang , Jianqiao Yi , Rui Zheng , Haocong Liao , Muzammal Hussain , Yaoquan Tu , Xiaoyun Lu , Yang Zhou

Inference-time control of diffusion models aims to steer model outputs to satisfy new constraints without retraining. Previous approaches have mostly relied on heuristic guidance or have been coupled with Sequential Monte Carlo (SMC) for…

Increasing the resolution of image sensors has been a never ending struggle since many years. In this paper, we propose a novel image sensor layout which allows for the acquisition of images at a higher resolution and improved quality. For…

图像与视频处理 · 电气工程与系统科学 2022-04-28 Jürgen Seiler , Markus Jonscher , Thomas Ussmueller , André Kaup

In this article, we propose an efficient method for sampling the relevant state space in condensed phase reactions. In the present method, the reaction is described by solving the electronic Schr\"{o}dinger equation for the solute atoms in…

化学物理 · 物理学 2009-11-10 Radu Iftimie , Dennis Salahub , Jeremy Schofield

This work proposes an extension of phase change and latent heat models for the simulation of metal powder bed fusion additive manufacturing processes on the macroscale and compares different models with respect to accuracy and numerical…

计算工程、金融与科学 · 计算机科学 2021-09-07 Sebastian D. Proell , Wolfgang A. Wall , Christoph Meier