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Diffraction-limited imaging through complex scattering media is a long sought after goal with important applications in biomedical research. In recent years, high resolution wavefront-shaping has emerged as a powerful approach to generate a…

光学 · 物理学 2014-10-17 Ori Katz , Eran Small , Yefeng Guan , Yaron Silberberg

Multifocus microscopy enables recording of entire volumes in a single camera exposure. In dense samples, multifocus microscopy is severely hampered by background haze. Here, we introduce a scalable multifocus method that incorporates…

Complementary to conventional and phase X-ray radiography, dark-field imaging has become central in visualizing diffusive scattering signal due to the spatially-unresolved texture within an object. To date most diffusive-dark-field…

医学物理 · 物理学 2023-03-21 Mario A. Beltran , David M. Paganin , Michelle K. Croughan , Kaye S. Morgan

Volumetric optical microscopy using non-diffracting beams enables rapid imaging of 3D volumes by projecting them axially to 2D images but lacks crucial depth information. Addressing this, we introduce MicroDiffusion, a pioneering tool…

图像与视频处理 · 电气工程与系统科学 2024-03-19 Mude Hui , Zihao Wei , Hongru Zhu , Fei Xia , Yuyin Zhou

Imaging with hard x-rays is an invaluable tool in medicine, biology, materials science, and cultural heritage. Propagation-based x-ray phase-contrast imaging and tomography have been mostly used to resolve micrometer-scale structures inside…

图像与视频处理 · 电气工程与系统科学 2025-06-02 Margie P. Olbinado , David M. Paganin , Yin Cheng , Alexander Rack

A unified method for three-dimensional reconstruction of objects from transmission images collected at multiple illumination directions is described. The method may be applicable to experimental conditions relevant to absorption-based,…

医学物理 · 物理学 2022-12-07 Timur E. Gureyev , Hamish G. Brown , Harry M. Quiney , Leslie J. Allen

Energy-dispersive X-ray diffraction (EDXRD) is extremely insensitive to sample morphology when implemented in a back-reflection geometry. The capabilities of this non-invasive technique for cultural heritage applications have been explored…

仪器与探测器 · 物理学 2021-11-19 Craig I. Hiley , Graeme M. Hansford , Nicholas Eastaugh

Ptychography is a popular technique to achieve diffraction limited resolution images of a two or three dimensional sample using high frame rate detectors. We introduce a relaxation of common projection algorithms to account for…

光学 · 物理学 2013-10-08 Stefano Marchesini , Andre Schirotzek , Chao Yang , Hau-tieng Wu , Filipe Maia

3D image reconstruction from a set of X-ray projections is an important image reconstruction problem, with applications in medical imaging, industrial inspection and airport security. The innovation of X-ray emitter arrays allows for a…

医学物理 · 物理学 2016-11-23 Maria Klodt , Raphael Hauser

Confocal microscopy is the standard approach for obtaining volumetric images of a sample with high axial and lateral resolution, especially when dealing with scattering samples. Unfortunately, a confocal microscope is quite expensive…

Three-dimensional segmentation in magnetic resonance images (MRI), which reflects the true shape of the objects, is challenging since high-resolution isotropic MRIs are rare and typical MRIs are anisotropic, with the out-of-plane dimension…

图像与视频处理 · 电气工程与系统科学 2023-03-15 Hanxue Gu , Hongyu He , Roy Colglazier , Jordan Axelrod , Robert French , Maciej A Mazurowski

Optical scattering presents a major obstacle to high resolution imaging in biological tissue and other turbid media. Conventional photoacoustic imaging can partially overcome this obstacle, enabling imaging of optical absorption in the…

Research and medicine rely on non-invasive optical techniques to image living tissue with high resolution in space and time. But so far a single data acquisition could not provide entirely diffraction-limited tomographic volumes of rapidly…

We propose approaches based on deep learning to localize objects in images when only a small training dataset is available and the images have low quality. That applies to many problems in medical image processing, and in particular to the…

计算机视觉与模式识别 · 计算机科学 2018-11-20 Aaron Pries , Peter J. Schreier , Artur Lamm , Stefan Pede , Jürgen Schmidt

Diffraction limit is manifested in the loss of high spatial frequency information that results from decay of evanescent waves. As a result, conventional far-field optics yields no information about an object's subwavelength features. Here…

光学 · 物理学 2012-01-24 Leonid Alekseyev , Evgenii Narimanov , Jacob Khurgin

We have developed an improved method of time-resolved x-ray reflectivity (XRR) using monochromatic synchrotron radiation. Our method utilizes a polycapillary x-ray optic to create a range of incident angles and an area detector to collect…

材料科学 · 物理学 2019-03-27 Howie Joress , Shane Quinlan Arlington , Timothy P. Weihs , Joel D. Brock , Arthur Woll

We propose a three-dimensional nonlinear diffusion method to implement the similar autofocusing function of multiple micro-objects and simultaneously remove the defocused images, which can distinguish the locations of certain sized…

计算机视觉与模式识别 · 计算机科学 2019-08-15 Wei-Na Li , Zhengyun Zhang , Jianshe Ma , Xiaohao Wang , Ping Su

Noise is a significant challenge in imaging. Conventional intensity-based techniques mitigate noise through various filtering methods, but they often require prior knowledge of noise characteristics and struggle, especially under low-light…

光学 · 物理学 2026-05-12 Pranay Mohta , Keval Moliya , Aniket Nag , Shaurya Aarav , Anand Kumar Jha

Diffusion-based image generators can now produce high-quality and diverse samples, but their success has yet to fully translate to 3D generation: existing diffusion methods can either generate low-resolution but 3D consistent outputs, or…

计算机视觉与模式识别 · 计算机科学 2023-08-29 Animesh Karnewar , Niloy J. Mitra , Andrea Vedaldi , David Novotny

The ability to resolve and quantify features at submicrometer scales from a single-shot image is crucial for real-time uncovering intricate structures in unlabeled biological samples and analyzing them at the subcellular level. We introduce…

光学 · 物理学 2025-01-22 Jaromír Běhal , Miroslav Ježek