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The simulation of blood flow and pressure in arteries requires outflow boundary conditions that incorporate models of downstream domains. We previously described a coupled multidomain method to couple analytical models of the downstream…

医学物理 · 物理学 2020-07-17 Irene Vignon-Clementel , C. A. Figueroa , K. E. Jansen , C. A. Taylor

The article focuses on determining the predictive uncertainty of a model on the example of atrial fibrillation detection problem by a single-lead ECG signal. To this end, the model predicts parameters of the beta distribution over class…

计算机视觉与模式识别 · 计算机科学 2018-08-08 Alexander Kuvaev , Roman Khudorozhkov

Machine learning models that utilize patient data across time (rather than just the most recent measurements) have increased performance for many risk stratification tasks in the intensive care unit. However, many of these models and their…

机器学习 · 计算机科学 2021-09-24 Nari Johnson , Sonali Parbhoo , Andrew Slavin Ross , Finale Doshi-Velez

The aim of this paper is to study the (clinical) time-series data of three diseases with complex dynamics: Parkinson's disease, Huntington's disease and Amyotrophic Lateral Sclerosis. For this purpose, first all of the time series data are…

其他定量生物学 · 定量生物学 2014-01-06 Farshad Merrikh-Bayat

Sepsis, characterized by a dysregulated immune response to infection, results in significant mortality, morbidity, and healthcare costs. The timely prediction of sepsis progression is crucial for reducing adverse outcomes through early…

机器学习 · 计算机科学 2026-01-01 Alireza Rafiei , Farshid Hajati , Alireza Rezaee , Amirhossien Panahi , Shahadat Uddin

Early hospital mortality prediction is critical as intensivists strive to make efficient medical decisions about the severely ill patients staying in intensive care units. As a result, various methods have been developed to address this…

机器学习 · 计算机科学 2019-02-12 Reza Sadeghi , Tanvi Banerjee , William Romine

The predictability of a time series is determined by the sensitivity to initial conditions of its data generating process. In this paper our goal is to characterize this sensitivity from a finite sample by assuming few hypotheses on the…

混沌动力学 · 物理学 2012-12-13 Quentin Giai Gianetto , Jean-Marc Le Caillec , Erwan Marrec

We analyzed the heartbeat time series of 12 human subjects exposed to progressive central hypovolemia with lower body negative pressure. Two data processing techniques based on wavelet transforms were used to determine the change in the…

统计力学 · 物理学 2007-05-23 Bruce J. West , Nicola Scafetta , William H. Cooke , Rita Balocchi

We focus on various measures of the fluctuations of the sequence of intervals between beats of the human heart, and how such fluctuations can be used to assess the presence or likelihood of cardiovascular disease. We examine sixteen such…

The lack of large video databases obtained from real patients with respiratory disorders makes the design and optimization of video-based monitoring systems quite critical. The purpose of this study is the development of suitable models and…

应用统计 · 统计学 2023-07-14 Davide Alinovi , Gianluigi Ferrari , Francesco Pisani , Riccardo Raheli

The development of an algorithm with related mathematical concepts and supporting hypothesis for detecting changes in system dynamics from time series along with empirical analysis and theoretical justification is presented. For the method,…

信号处理 · 电气工程与系统科学 2020-06-30 Ferdaus Kawsar , Mohammad Adibuzzaman

Recent research has shown that each apnea episode results in a significant rise in the beat-to-beat blood pressure and by a drop to the pre-episode levels when patient resumes normal breathing. While the physiological implications of these…

信号处理 · 电气工程与系统科学 2018-11-19 Armin Soltan Zadi , Raichel M. Alex , Rong Zhang , Donald E. Watenpaugh , Khosrow Behbehani

Disruptions in the normal rhythmic functioning of the heart, termed as arrhythmia, often result from qualitative changes in the excitation dynamics of the organ. The transitions between different types of arrhythmia are accompanied by…

组织与器官 · 定量生物学 2016-01-21 Pavithraa Seenivasan , Soumya Easwaran , S. Sridhar , Sitabhra Sinha

The Electrocardiograph signal represents the heart's electrical activity while blood pressure results from the heart's mechanical activity. Previous studies have investigated how the heart's electrical and mechanical activities are related…

信号处理 · 电气工程与系统科学 2020-08-25 Seyedeh Somayyeh Mousavi , Mostafa Charmi , Mohammad Firouzmand , Mohammad Hemmati , Maryam Moghadam , Yadollah Ghorbani

Heart disease remains the leading cause of death in the United States. Compared with risk assessment guidelines that require manual calculation of scores, machine learning-based prediction for disease outcomes such as mortality can be…

机器学习 · 计算机科学 2018-12-13 Laura A. Barrett , Seyedeh Neelufar Payrovnaziri , Jiang Bian , Zhe He

A model of the heart tissue as a conductive system with two interacting pacemakers and a refractory time, is proposed. In the parametric space of the model the phase locking areas are investigated in detail. Obtained results allow us to…

混沌动力学 · 物理学 2007-05-23 Alexander Loskutov , Sergei Rybalko , Ekaterina Zhuchkova

Improving health worldwide will require rigorous quantification of population-level trends in health status. However, global-level surveys are not available, forcing researchers to rely on fragmentary country-specific data of varying…

统计方法学 · 统计学 2014-05-20 Mariel M. Finucane , Christopher J. Paciorek , Goodarz Danaei , Majid Ezzati

Clinical guidance systems have been widely adopted to help medical staffs to avoid preventable medical errors such as delay in diagnosis, treatment or untended deviations from best practice guidelines. However, because patient condition…

计算机与社会 · 计算机科学 2016-10-24 Maryam Rahmaniheris , Yu Jiang , Lui Sha

Left ventricular (LV) function is an important factor in terms of patient management, outcome, and long-term survival of patients with heart disease. The most recently published clinical guidelines for heart failure recognise that over…

Reentry around non-conducting ventricular scar tissue, which often causes lethal arrhythmias, is typically treated by rapid stimulation from an implantable defibrillator. However, the mechanisms of termination (success and failure) are…

混沌动力学 · 物理学 2007-05-23 Sitabhra Sinha , David J. Christini