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Routinely navigating through an ever-changing and unsteady environment, and utilizing chemical energy, molecular motors transport the cell's crucial components, such as neurotransmitters and organelles. They generate force and pull cargo,…

生物物理 · 物理学 2012-09-28 Bartosz Lisowski , Michał Żabicki

In systems possessing a spatial or dynamical symmetry breaking thermal Brownian motion combined with unbiased, non-equilibrium noise gives rise to a channelling of chance that can be used to exercise control over systems at the micro- and…

统计力学 · 物理学 2009-11-10 P. Hänggi , F. Marchesoni , F. Nori

Transport phenomena in spatially periodic systems far from thermal equilibrium are considered. The main emphasize is put on directed transport in so-called Brownian motors (ratchets), i.e. a dissipative dynamics in the presence of thermal…

统计力学 · 物理学 2009-10-31 Peter Reimann

Properties of transport of molecular motors are investigated. A simplified model based on the concept of Brownian ratchets is applied. We analyze a stochastic equation of motion by means of numerical methods. The transport is systematically…

统计力学 · 物理学 2011-12-07 Lukasz Machura , Marcin Kostur , Jerzy Luczka

A molecular motor is made of either a single macromolecule or a macromolecular complex. Just like their macroscopic counterparts, molecular motors "transduce" input energy into mechanical work. All the nano-motors considered here operate…

生物物理 · 物理学 2013-07-18 Debashish Chowdhury

In systems possessing spatial or dynamical symmetry breaking, Brownian motion combined with symmetric external input signals, deterministic or random, alike, can assist directed motion of particles at the submicron scales. In such cases,…

统计力学 · 物理学 2009-06-05 Peter Hanggi , Fabio Marchesoni

Biological functions in each animal cell depend on coordinated operations of a wide variety of molecular motors. Some of the these motors transport cargo to their respective destinations whereas some others are mobile workshops which…

生物物理 · 物理学 2008-03-07 Debashish Chowdhury

The problem of transport through nanochannels is one of the major questions in cell biology, with a wide range of applications. Brownian ratchets are fundamental in various biochemical processes, and are roughly divided into two categories:…

软凝聚态物质 · 物理学 2013-07-24 Anna Lappala , Alessio Zaccone , Eugene M. Terentjev

Molecular machines consist of either a single protein or a macromolecular complex composed of protein and RNA molecules. Just like their macroscopic counterparts, each of these nano-machines has an engine that "transduces" input energy into…

生物物理 · 物理学 2012-03-15 Debashish Chowdhury

The transport of interacting Brownian particles in a periodic asymmetric (ratchet) substrate is studied numerically. In a zero-temperature regime, the system behaves as a reversible step motor, undergoing multiple sign reversals of the…

统计力学 · 物理学 2008-12-31 Rogério M. da Silva , Clécio C. de Souza Silva , Sérgio Coutinho

The muscle contraction, operation of ATP synthase, maintaining the shape of a cell are believed to be secured by motor proteins, which can be modelled using the Brownian ratchet mechanism. We consider the randomly flashing ratchet model of…

经典分析与常微分方程 · 数学 2013-05-09 Dmitry Vorotnikov

We study a noisy drive mechanism for efficiency enhancement of Brownian motors operating on the micro-scale domain. It was proven [J. Spiechowicz et al., J. Stat. Mech. P02044, (2013)] that biased noise $\eta(t)$ can induce normal and…

统计力学 · 物理学 2014-09-09 Jakub Spiechowicz , Peter Hänggi , Jerzy Łuczka

Recent experiments reveal both passive subdiffusion of various nanoparticles and anomalous active transport of such particles by molecular motors in the molecularly crowded environment of living biological cells. Passive and active…

生物物理 · 物理学 2014-03-24 Igor Goychuk , Vasyl O. Kharchenko , R. Metzler

Multiple experiments show that various submicron particles such as magnetosomes, RNA messengers, viruses, and even much smaller nanoparticles such as globular proteins diffuse anomalously slow in viscoelastic cytosol of living cells. Hence,…

生物物理 · 物理学 2018-11-12 Igor Goychuk

We give an overview over recent studies on the model of Active Brownian Motion (ABM) coupled to reservoirs providing free energy which may be converted into kinetic energy of motion. First, we present an introduction to a general concept of…

数据分析、统计与概率 · 物理学 2009-11-13 Alessandro Fiasconaro , Werner Ebeling , Ewa Gudowska-Nowak

We propose a stochastic process wherein molecular transport is mediated by asymmetric nucleation of domains on a one-dimensional substrate. Track-driven mechanisms of molecular transport arise in biophysical applications such as Holliday…

统计力学 · 物理学 2009-11-13 Amit Lakhanpal , Tom Chou

We investigate the transport properties of particles driven by colored noise in a flashing ratchet potential, focusing on both non-interacting and single-file interacting regimes. The model incorporates memory effects via a non-Markovian…

软凝聚态物质 · 物理学 2025-12-18 Karina I. Mazzitello , Daniel G. Zarlenga , Constancio M. Arizmendi

A ratchet model for coupled Brownian motors, inspired by the motion of individual two-headed molecular motors on cytoskeletal filaments, is proposed. Such motors are modeled as two elastically coupled Brownian particles, each of which moves…

软凝聚态物质 · 物理学 2009-11-07 Debasis Dan , A. M. Jayannavar , Gautam I. Menon

Processive molecular motors which drive the traffic of organelles in cells move in a directed way along cytoskeletal filaments. On large time scales, they perform motor walks, i.e., peculiar random walks which arise from the repeated…

统计力学 · 物理学 2007-05-23 Stefan Klumpp , Theo M. Nieuwenhuizen , Reinhard Lipowsky

The noise-flatness-induced hypersensitive transport of overdamped Brownian particles in a tilted ratchet system driven by multiplicative nonequilibrium three-level Markovian noise and additive white noise is considered. At low temperatures…

统计力学 · 物理学 2007-05-23 Romi Mankin , Astrid Haljas , Risto Tammelo , Dmitri Martila
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