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The mammalian cortex is divided into architectonic and functionally distinct areas. There is growing experimental evidence that their emergence and development is controlled by both epigenetic and genetic factors. The latter were recently…

神经元与认知 · 定量生物学 2007-05-23 Jan Karbowski , G. B. Ermentrout

The formation of three-dimensional structures during the epitaxial growth of films is associated to the reflection of diffusing particles in descending terraces due to the presence of the so-called Ehrlich-Schwoebel (ES) barrier. We…

统计力学 · 物理学 2011-09-23 F. F. Leal , T. J. Oliveira , S. C. Ferreira

Animals flexibly change their behavior depending on context. It is reported that the hippocampus is one of the most prominent regions for contextual behaviors, and its sequential activity shows context dependency. However, how such…

神经元与认知 · 定量生物学 2026-03-19 Yoshiki Ito , Taro Toyoizumi

Learning features invariant to arbitrary transformations in the data is a requirement for any recognition system, biological or artificial. It is now widely accepted that simple cells in the primary visual cortex respond to features while…

神经与进化计算 · 计算机科学 2020-12-14 Jayanta K. Dutta , Bonny Banerjee

Detailed knowledge of mechanical parameters such as cell elasticity, stiffness of the growth substrate, or traction stresses generated during axonal extensions is essential for understanding the mechanisms that control neuronal growth. Here…

生物物理 · 物理学 2013-04-05 Elise Spedden , James D. White , Elena N. Naumova , David L. Kaplan , Cristian Staii

We develop a stochastic epidemic model progressing over dynamic networks, where infection rates are heterogeneous and may vary with individual-level covariates. The joint dynamics are modeled as a continuous-time Markov chain such that…

统计方法学 · 统计学 2021-12-16 Fan Bu , Allison E. Aiello , Alexander Volfovsky , Jason Xu

Typically, metallic systems localized under strong disorder exhibit a transition to \imk{delocalization} %finite conduction as kinetic terms increase. In this work, we reveal the opposite effect~--~increasing kinetic terms leads to an…

无序系统与神经网络 · 物理学 2025-07-03 Roopayan Ghosh , Madhumita Sarkar , Ivan M. Khaymovich

Humans can learn several tasks in succession with minimal mutual interference but perform more poorly when trained on multiple tasks at once. The opposite is true for standard deep neural networks. Here, we propose novel computational…

神经元与认知 · 定量生物学 2022-09-07 Timo Flesch , David G. Nagy , Andrew Saxe , Christopher Summerfield

Reinforcement learning consists of finding policies that maximize an expected cumulative long-term reward in a Markov decision process with unknown transition probabilities and instantaneous rewards. In this paper, we consider the problem…

系统与控制 · 计算机科学 2018-07-31 Santiago Paternain , Juan Andrés Bazerque , Austin Small , Alejandro Ribeiro

We present a scheme for sequential decision making with a risk-sensitive objective and constraints in a dynamic environment. A neural network is trained as an approximator of the mapping from parameter space to space of risk and policy with…

人工智能 · 计算机科学 2019-07-10 Shuai Ma , Jia Yuan Yu , Ahmet Satir

Recently, various deep neural networks have been applied to classify electroencephalogram (EEG) signal. EEG is a brain signal that can be acquired in a non-invasive way and has a high temporal resolution. It can be used to decode the…

神经与进化计算 · 计算机科学 2021-07-16 Ji-Seon Bang , Seong-Whan Lee

How the brain co-ordinates the actions of distant regions in an efficient manner is an open problem. Many believe that cross-frequency coupling between the amplitude of high frequency local field potential oscillations in one region and the…

神经元与认知 · 定量生物学 2016-04-04 Thomas E. Gorochowski , Rafal Bogacz , Matthew Jones

Theories of localised pattern formation are important to understand a broad range of natural patterns, but are less well-understood than more established mechanisms of domain-filling pattern formation. Here, we extend recent work on pattern…

斑图形成与孤子 · 物理学 2025-07-22 Andrew L. Krause , Václav Klika , Edgardo Villar-Sepúlveda , Alan R. Champneys , Eamonn A. Gaffney

Spatial navigation in mammals is based on building a mental representation of their environment---a cognitive map. However, both the nature of this cognitive map and its underpinning in neural structures and activity remains vague. A key…

神经元与认知 · 定量生物学 2016-03-22 A. Babichev , S. Cheng , Yu. Dabaghian

The amount of power in different frequency bands of the electroencephalogram (EEG) carries information about the behavioral state of a subject. Hence, neurologists treating epileptic patients monitor the temporal evolution of the different…

神经元与认知 · 定量生物学 2020-06-17 Melisa Maidana Capitán , Nuria Cámpora , Claudio Sebastián , Sigvard Silvia Kochen , Inés Samengo

Retinal imaging has emerged as a promising method of addressing this challenge, taking advantage of the unique structure of the retina. The retina is an embryonic extension of the central nervous system, providing a direct in vivo window…

计算机视觉与模式识别 · 计算机科学 2024-09-24 Syed Javed , Tariq M. Khan , Abdul Qayyum , Arcot Sowmya , Imran Razzak

Topographic maps are a brain structure connecting pre-synpatic and post-synaptic brain regions. Topographic development is dependent on Hebbian-based plasticity mechanisms working in conjunction with spontaneous patterns of neural activity…

神经元与认知 · 定量生物学 2025-01-15 Nicholas Gale , Jennifer Rodger , Michael Small , Stephen Eglen

Ising model with quenched random magnetic fields is examined for single Gaussian, bimodal and double Gaussian random field distributions by introducing an effective field approximation that takes into account the correlations between…

统计力学 · 物理学 2016-08-14 Yusuf Yüksel , Ümit Akıncı , Hamza Polat

Seizure detection from EEGs is a challenging and time consuming clinical problem that would benefit from the development of automated algorithms. EEGs can be viewed as structural time series, because they are multivariate time series where…

机器学习 · 计算机科学 2019-05-07 Ian Covert , Balu Krishnan , Imad Najm , Jiening Zhan , Matthew Shore , John Hixson , Ming Jack Po

From a coarse-grained perspective the motif of a self-activating species, activating a second species which acts as its own repressor, is widely found in biological systems, in particular in genetic systems with inherent oscillatory…

生物物理 · 物理学 2016-01-20 Darka Labavic , Hannes Nagel , Wolfhard Janke , Hildegard Meyer-Ortmanns