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Recent research has shown that motile cells can adapt their mode of propulsion to the mechanical properties of the environment in which they find themselves--crawling in some environments while swimming in others. The latter can involve…

生物物理 · 物理学 2018-05-24 Hao Wu , Marco Avila Ponce de Leon , Hans G. Othmer

A simple kinetic model of a two-component deformable and reactive bilayer is presented. The two differently shaped components are interconverted by a nonequilibrium reaction, and a phenomenological coupling between local composition and…

软凝聚态物质 · 物理学 2009-11-11 Ramon Reigada , Javier Buceta , Katja Lindenberg

Motor-proteins are responsible for transport inside cells. Harnessing their activity is key towards developing new nano-technologies, or functional biomaterials. Cytoskeleton-like networks, recently tailored in vitro, result from the…

软凝聚态物质 · 物理学 2016-06-21 Pau Guillamat , Jordi Ignés-Mullol , Francesc Sagués

Lipid bilayer membranes below their main transition have two tilt order parameters, corresponding to the two monolayers. These two tilts may be strongly coupled to membrane shape but only weakly coupled to each other. We discuss some…

软凝聚态物质 · 物理学 2009-10-28 Udo Seifert , Julian Shillcock , Philip Nelson

Near a critical point, the time scale of thermally-induced fluctuations diverges in a manner determined by the dynamic universality class. Experiments have verified predicted 3D dynamic critical exponents in many systems, but similar…

统计力学 · 物理学 2015-05-27 Aurelia R. Honerkamp-Smith , Benjamin B. Machta , Sarah L. Keller

We consider the hydrodynamics of lipid bilayers containing transmembrane proteins of arbitrary shape. This biologically-motivated problem is relevant to the cell membrane, whose fluctuating dynamics play a key role in phenomena ranging from…

软凝聚态物质 · 物理学 2016-10-10 Andrew Callan-Jones , Marc Durand , Jean-Baptiste Fournier

Biological membranes constitute boundaries of cells and cell organelles. Physico-chemical mechanisms at the atomic scale are dictated by protein-lipid interaction strength, lipid composition, lipid distribution in the vicinity of the…

生物物理 · 物理学 2015-10-19 N. Ramakrishnan , P. B. Sunil Kumar , Ravi Radhakrishnan

Nonequilibrium membrane pattern formation is studied using meshless membrane simulation. We consider that molecules bind to either surface of a bilayer membrane and move to the opposite leaflet by flip--flop. When binding does not modify…

软凝聚态物质 · 物理学 2025-01-14 Hiroshi Noguchi

We study a continuum model of the lipid bilayer based on minimizing the free energy of a mixture of water and lipid molecules. This paper extends previous work by Blom & Peletier (2004) in the following ways. (a) It formulates a more…

软凝聚态物质 · 物理学 2020-06-05 Phillip L. Wilson , Huaxiong Huang , Shu Takagi

In embryonic development, programmed cell shape changes are essential for building functional organs, but in many cases the mechanisms that precisely regulate these changes remain unknown. We propose that fluid-like drag forces generated by…

生物物理 · 物理学 2019-01-03 Gonca Erdemci-Tandogan , Madeline J. Clark , Jeffrey D. Amack , M. Lisa Manning

Biomembranes consisting of two opposing phospholipid monolayers, which comprise the so-called lipid bilayer, are largely responsible for the dual solid-fluid behavior of individual cells and viruses. Quantifying the mechanical…

生物物理 · 物理学 2024-05-27 Naoki Takeishi , Masaya Santo , Naoto Yokoyama , Shigeo Wada

In biology, cells undergo deformations under the action of flow caused by the fluid surrounding them. These flows lead to shape changes and instabilities that have been explored in detail for single component vesicles. However, cell…

流体动力学 · 物理学 2025-10-15 Anirudh Venkatesh , Vivek Narsimhan

The study of interactions between biomimetic membranes and micron-sized particles is crucial for understanding various biological processes. Here, we control microparticle spontaneous engulfment by giant lipid vesicles by tuning particle…

软凝聚态物质 · 物理学 2025-01-22 Clément Marque , Gaetano D'Avino , Domenico Larobina , Aude Michel , Ali Abou-Hassan , Antonio Stocco

The macroscopic behaviour of active matter arises from nonequilibrium microscopic processes. In soft materials, active stresses typically drive macroscopic shape changes, which in turn alter the geometry constraining the microscopic…

软凝聚态物质 · 物理学 2024-11-26 Tim Dullweber , Roman Belousov , Anna Erzberger

The rich thermotropic behavior of lipid bilayers is addressed using phenomenological theory informed by many experiments. The most recent experiment not yet addressed by theory has shown that the tilt modulus in DMPC lipid bilayers…

软凝聚态物质 · 物理学 2023-07-12 John F. Nagle

Cells modify their volume in response to changes in osmotic pressure but it is usually assumed that other active shape variations do not involve significant volume fluctuations. Here we report experiments demonstrating that water transport…

Cells are defined by lipid membranes that differ in their structure across the tree of life. While the membranes of most bacteria and eukaryotes consist of single-headed bilayer lipids, the membranes of archaea are composed of mixtures of…

软凝聚态物质 · 物理学 2026-04-21 Felix Frey , Miguel Amaral , Anđela Šarić

Biological cells with all of their surface structure and complex interior stripped away are essentially vesicles - membranes composed of lipid bilayers which form closed sacs. Vesicles are thought to be relevant as models of primitive…

统计力学 · 物理学 2015-05-18 Pietro de Anna , Francesca Di Patti , Duccio Fanelli , Alan J. McKane , Thierry Dauxois

It was recently discovered that friction between surfaces bearing phosphatidylcholine (PC) lipid bilayers can be increased by two orders of magnitude or more via an externally-applied electric field, and that this increase is fully…

软凝聚态物质 · 物理学 2024-09-26 Di Jin , Jacob Klein

Living systems are chiral on multiple scales, from constituent biopolymers to large scale morphology, and their active mechanics is both driven by chiral components and serves to generate chiral morphologies. We describe the mechanics of…

软凝聚态物质 · 物理学 2023-07-03 Sami C. Al-Izzi , Gareth P. Alexander