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A phenomenological description for active bundles of polar filaments is presented. The activity of the bundle results from crosslinks, that induce relative displacements between the aligned filaments. Our generic description is based on…

统计力学 · 物理学 2009-11-07 Karsten Kruse , Frank Julicher

The crawling motion of Dictyostelium discoideum on substrata involves a number of coordinated events including cell contractions and cell protrusions. The mechanical forces exerted on the substratum during these contractions have recently…

生物物理 · 物理学 2009-12-04 Mathias Buenemann , Herbert Levine , Wouter-Jan Rappel , Leonard M. Sander

We consider a two-dimensional athermal binary mixture of Lennard-Jones particles with persistent random active forces. The liquid phase of this system for active forces exceeding a threshold value exhibits self-organization with long-range…

软凝聚态物质 · 物理学 2025-12-24 Atharva Shukla , Chandan Dasgupta

Unicellular organisms exhibit elaborate collective behaviors in response to environmental cues. These behaviors are controlled by complex biochemical networks within individual cells and coordinated through cell-to-cell communication.…

细胞行为 · 定量生物学 2015-06-24 Javad Noorbakhsh , David Schwab , Allyson Sgro , Thomas Gregor , Pankaj Mehta

We have proposed a method for the dynamic simulation of a collection of self-propelled particles in a viscous Newtonian fluid. We restrict attention to particles whose size and velocity are small enough that the fluid motion is in the…

软凝聚态物质 · 物理学 2015-05-13 Vishwajeet Mehandia , Prabhu R. Nott

Studies of particle motion in vortical flows have mainly focused on point-like particles, either inertial or self-propelled. This approximation assumes that the velocity field that surrounds the particle is linear. We consider an…

流体动力学 · 物理学 2022-01-17 Sumithra Reddy Yerasi , Rama Govindarajan , Dario Vincenzi

Recent studies of the phase diagram for spherical, purely repulsive, active particles established the existence of a transition from a liquid-like to a solid-like phase analogous to the one observed in colloidal systems at thermal…

Coordination of cytoplasmic flows on large scales in space and time are at the root of many cellular processes, including growth, migration or division. These flows are driven by organized contractions of the actomyosin cortex. In order to…

适应与自组织系统 · 物理学 2022-07-29 Busson Valentin , Saiseau Raphaël , Durand Marc

We study a continuum model of overdamped self-propelled particles with an aligning interaction in two dimensions. By combining analytical and numerical work, we map out the phase diagram for generic parameters. We find that the system…

生物物理 · 物理学 2011-12-30 Arvind Gopinath , Michael F. Hagan , M. Cristina Marchetti , Aparna Baskaran

The behaviour of an organism often reflects a strategy for coping with its environment. Such behaviour in higher organisms can often be reduced to a few stereotyped modes of movement due to physiological limitations, but finding such modes…

细胞行为 · 定量生物学 2013-08-26 Luke Tweedy , Börn Meier , Jürgen Stephan , Doris Heinrich , Robert G. Endres

The swimming of cells, far from any boundary, can arise in the absence of long-range liquid-crystalline order within the cytoplasm, but simple models of this effect are lacking. Here we present a two-dimensional model of droplet…

软凝聚态物质 · 物理学 2020-07-29 Rajesh Singh , Elsen Tjhung , Michael E. Cates

Life in complex systems, such as cities and organisms, comes to a standstill when global coordination of mass, energy, and information flows is disrupted. Global coordination is no less important in single cells, especially in large oocytes…

Morphogenesis emerges from dynamic feedback among geometry, mechanics, and chemistry; however, disentangling these contributions in living systems remains challenging. Here, we focus on the interplay between geometry and mechanics by…

The migration of cells is relevant for processes such as morphogenesis, wound healing, and invasion of cancer cells. In order to move, single cells deform cyclically. However, it is not understood how these shape oscillations influence…

生物物理 · 物理学 2019-09-04 Matteo Campo , Simon K. Schnyder , John J. Molina , Thomas Speck , Ryoichi Yamamoto

Here we show that coupling to curvature has profound effects on collective motion in active systems, leading to patterns not observed in flat space. Biological examples of such active motion in curved environments are numerous: curvature…

软凝聚态物质 · 物理学 2015-03-05 Rastko Sknepnek , Silke Henkes

Eukaryotic cell motility involves a complex network of interactions between biochemical components and mechanical processes. The cell employs this network to polarize and induce shape changes that give rise to membrane protrusions and…

细胞行为 · 定量生物学 2022-01-03 E. Moreno , S. Flemming , F. Font , M. Holschneider , C. Beta , S. Alonso

We present a Lattice-Boltzmann method for simulating self-propelling (active) colloidal particles in two-dimensions. Active particles with symmetric and asymmetric force distribution on its surface are considered. The velocity field…

软凝聚态物质 · 物理学 2009-11-11 Sanoop Ramachandran , P. B. Sunil Kumar , I. Pagonabarraga

We report here a peculiar dynamically ordered state of clustering droplets of a mixture of organic solvent. There droplets are driven by the solutal Marangoni effect on the surface of aqueous surfactant solution. They form temporal ring…

软凝聚态物质 · 物理学 2017-06-02 Shinpei Tanaka , Takeshi Kano

We study dynamic self-organisation and order-disorder transitions in a two-dimensional system of self-propelled particles. Our model is a variation of the Vicsek model, where particles align the motion to their neighbours but repel each…

统计力学 · 物理学 2013-05-02 Maksym Romenskyy , Vladimir Lobaskin

Ensembles of particles rotating in a two-dimensional fluid can exhibit chaotic dynamics yet develop signatures of hidden order. Such "rotors" are found in the natural world spanning vastly disparate length scales - from the rotor proteins…

软凝聚态物质 · 物理学 2022-03-09 Naomi Oppenheimer , David B. Stein , Matan Yah Ben Zion , Michael J. Shelley