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Traditional meta-analysis assumes that the effect sizes estimated in individual studies follow a Gaussian distribution. However, this distributional assumption is not always satisfied in practice, leading to potentially biased results. In…

统计方法学 · 统计学 2024-04-23 Wei Liang , Haicheng Huang , Hongsheng Dai , Yinghui Wei

In longitudinal studies, subjects may be lost to follow-up, or miss some of the planned visits, leading to incomplete response sequences. When the probability of non-response, conditional on the available covariates and the observed…

统计方法学 · 统计学 2017-07-10 Alessandra Spagnoli , Maria Francesca Marino , Marco Alfò

Target trial emulation (TTE) enables causal questions to be studied with observational data when randomized controlled trials (RCTs) are infeasible. Yet treatment-effect methods often address causal estimation, missingness, and temporal…

Missing data is a common issue in various fields such as medicine, social sciences, and natural sciences, and it poses significant challenges for accurate statistical analysis. Although numerous imputation methods have been proposed to…

统计方法学 · 统计学 2025-07-23 Seongmin Kim , Jeunghun Oh , Hungkuk Ko , Jeongmin Park , Jaeyong Lee

Dropout represents a typical issue to be addressed when dealing with longitudinal studies. If the mechanism leading to missing information is non-ignorable, inference based on the observed data only may be severely biased. A frequent…

统计方法学 · 统计学 2018-03-23 Maria Francesca Marino , Marco Alfo'

We develop a generally applicable full-information inference method for heterogeneous agent models, combining aggregate time series data and repeated cross sections of micro data. To handle unobserved aggregate state variables that affect…

计量经济学 · 经济学 2024-11-19 Laura Liu , Mikkel Plagborg-Møller

Difficulties may arise when analyzing longitudinal data using mixed-effects models if there are nonparametric functions present in the linear predictor component. This study extends the use of semiparametric mixed-effects modeling in cases…

统计方法学 · 统计学 2024-02-05 Mozhgan Taavoni , Mohammad Arashi

The Difference-in-Differences (DiD) method is a fundamental tool for causal inference, yet its application is often complicated by missing data. Although recent work has developed robust DiD estimators for complex settings like staggered…

统计方法学 · 统计学 2026-01-27 Lorenzo Testa , Edward H. Kennedy , Matthew Reimherr

In this study, we introduce a sophisticated generative conditional strategy designed to impute missing values within datasets, an area of considerable importance in statistical analysis. Specifically, we initially elucidate the theoretical…

机器学习 · 统计学 2026-01-05 George Sun , Yi-Hui Zhou

Mixtures of Linear Regressions (MLR) is an important mixture model with many applications. In this model, each observation is generated from one of the several unknown linear regression components, where the identity of the generated…

机器学习 · 计算机科学 2020-03-31 Yuanzhi Li , Yingyu Liang

We carry out ANOVA comparisons of multiple treatments for longitudinal studies with missing values. The treatment effects are modeled semiparametrically via a partially linear regression which is flexible in quantifying the time effects of…

统计理论 · 数学 2012-11-14 Song Xi Chen , Ping-Shou Zhong

We study the effects of missingness on the estimation of population parameters. Moving beyond restrictive missing completely at random (MCAR) assumptions, we first formulate a missing data analogue of Huber's arbitrary…

Background: Multiple imputation is often used to reduce bias and gain efficiency when there is missing data. The most appropriate imputation method depends on the model the analyst is interested in fitting. Several imputation approaches…

统计方法学 · 统计学 2022-11-29 Matthew J. Smith , Matteo Quartagno , Edmund Njeru Njagi

Missing data are ubiquitous in medical research. Although there is increasing guidance on how to handle missing data, practice is changing slowly and misapprehensions abound, particularly in observational research. We present a practical…

We propose a comprehensive Bayesian joint modeling framework for zero-inflated longitudinal count data and time-to-event outcomes, explicitly incorporating a cure fraction to account for subjects who never experience the event. The…

统计方法学 · 统计学 2025-08-27 Taban Baghfalaki , Mojtaba Ganjali

Estimating population quantities such as mean outcomes from user feedback is fundamental to platform evaluation and social science, yet feedback is often missing not at random (MNAR): users with stronger opinions are more likely to respond,…

机器学习 · 统计学 2026-02-19 Hongyu Chen , David Simchi-Levi , Ruoxuan Xiong

Bayesian likelihood-free methods implement Bayesian inference using simulation of data from the model to substitute for intractable likelihood evaluations. Most likelihood-free inference methods replace the full data set with a summary…

统计方法学 · 统计学 2020-10-16 Yinan Mao , Xueou Wang , David J. Nott , Michael Evans

We propose a new statistical approach to obtain differential gene expression of non-detects in quantitative real-time PCR (qPCR) experiments through Bayesian hierarchical modeling. We propose to treat non-detects as non-random missing data,…

应用统计 · 统计学 2019-10-31 Valeriia Sherina , Matthew N. McCall , Tanzy M. T. Love

Models for analyzing multivariate data sets with missing values require strong, often unassessable, assumptions. The most common of these is that the mechanism that created the missing data is ignorable - a twofold assumption dependent on…

应用统计 · 统计学 2020-02-17 Iavor Bojinov , Natesh Pillai , Donald Rubin

Causal mediation analysis, pleiotropy analysis, and replication analysis are three highly popular genetic study designs. Although these analyses address different scientific questions, the underlying inference problems all involve…

统计方法学 · 统计学 2023-09-25 Ryan Sun , Zachary McCaw , Xihong Lin
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