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Current state-of-the-art large language models are effective in generating high-quality text and encapsulating a broad spectrum of world knowledge. These models, however, often hallucinate and lack locally relevant factual data.…

软件工程 · 计算机科学 2024-02-21 Anton Shapkin , Denis Litvinov , Yaroslav Zharov , Egor Bogomolov , Timur Galimzyanov , Timofey Bryksin

The synthesis of DNA strands remains the most costly part of the DNA storage system. Thus, to make DNA storage system more practical, the time and materials used in the synthesis process have to be optimized. We consider the most common…

信息论 · 计算机科学 2023-05-15 Johan Chrisnata , Han Mao Kiah , Van Long Phuoc Pham

The coverage depth problem in DNA data storage is about computing the expected number of reads needed to recover all encoded strands. Given a generator matrix of a linear code, this quantity equals the expected number of randomly drawn…

信息论 · 计算机科学 2026-03-09 Matteo Bertuzzo , Alberto Ravagnani , Eitan Yaakobi

This paper focuses on pattern matching in the DNA sequence. It was inspired by a previously reported method that proposes encoding both pattern and sequence using prime numbers. Although fast, the method is limited to rather small pattern…

计算机视觉与模式识别 · 计算机科学 2016-11-21 Janja Paliska Soldo , Ana Sovic Krzic , and Damir Sersic

The seriation problem seeks to reorder a set of elements given pairwise similarity information, so that elements with higher similarity are closer in the resulting sequence. When a global ordering consistent with the similarity information…

最优化与控制 · 数学 2018-06-05 Antoine Recanati , Nicolas Servant , Jean-Philippe Vert , Alexandre d'Aspremont

Typical engineering design tasks require the effort to modify designs iteratively until they meet certain constraints, i.e., performance or attribute requirements. Past work has proposed ways to solve the inverse design problem, where…

机器学习 · 计算机科学 2021-03-11 Amin Heyrani Nobari , Wei Chen , Faez Ahmed

The Pattern self-Assembly Tile set Synthesis (PATS) problem is to determine a set of coloured tiles that self-assemble to implement a given rectangular colour pattern. We give an exhaustive branch-and-bound algorithm to find tile sets of…

数据结构与算法 · 计算机科学 2015-03-13 Mika Göös , Pekka Orponen

We introduce and experimentally demonstrate the utility of tag-based genetic regulation, a new genetic programming (GP) technique that allows programs to dynamically adjust which code modules to express. Tags are evolvable labels that…

神经与进化计算 · 计算机科学 2021-07-13 Alexander Lalejini , Matthew Andres Moreno , Charles Ofria

Fragment-based shape signature techniques have proven to be powerful tools for computer-aided drug design. They allow scientists to search for target molecules with some similarity to a known active compound. They do not require reference…

人工智能 · 计算机科学 2022-01-05 Thierry Petit , Randy J. Zauhar

Consider the collection of all binary matrices having a specific sequence of row and column sums and consider sampling binary matrices uniformly from this collection. Practical algorithms for exact uniform sampling are not known, but there…

统计计算 · 统计学 2013-01-28 Matthew T. Harrison

Embedding image features into a binary Hamming space can improve both the speed and accuracy of large-scale query-by-example image retrieval systems. Supervised hashing aims to map the original features to compact binary codes in a manner…

机器学习 · 计算机科学 2016-11-17 Guosheng Lin , Chunhua Shen , Anton van den Hengel

Several modern applications involve huge graphs and require fast answers to reachability queries. In more than two decades since first proposals, several approaches have been presented adopting on-line searches, hop labelling or transitive…

数据结构与算法 · 计算机科学 2016-11-09 Nicolas Boria , Gianpiero Cabodi , Paolo Camurati , Marco Palena , Paolo Pasini , Stefano Quer

We analyze greedy algorithms for the Hierarchical Aggregation (HAG) problem, a strategy introduced in [Jia et al., KDD 2020] for speeding up learning on Graph Neural Networks (GNNs). The idea of HAG is to identify and remove redundancies in…

数据结构与算法 · 计算机科学 2021-02-09 Alexandra Porter , Mary Wootters

Branched junction molecule assembly of DNA nanostructures, pioneered by Seeman's laboratory in the 1980s, has become increasingly sophisticated, as have the assembly targets. A critical design step is finding minimal sets of branched…

Labeling data (e.g., labeling the people, objects, actions and scene in images) comprehensively and efficiently is a widely needed but challenging task. Numerous models were proposed to label various data and many approaches were designed…

机器学习 · 计算机科学 2020-02-14 Mu Yuan , Lan Zhang , Xiang-Yang Li , Hui Xiong

Predicting the cheapest sample size for the optimal stratification in multivariate survey design is a problem in cases where the population frame is large. A solution exists that iteratively searches for the minimum sample size necessary to…

统计方法学 · 统计学 2018-06-18 Mervyn O'Luing , Steven Prestwich , S. Armagan Tarim

Alphabetic codes and binary search trees are combinatorial structures that abstract search procedures in ordered sets endowed with probability distributions. In this paper, we design new linear-time algorithms to construct alphabetic codes,…

信息论 · 计算机科学 2024-07-24 Roberto Bruno , Roberto De Prisco , Alfredo De Santis , Ugo Vaccaro

This work aims to study and explore the use of Gene Expression Programming (GEP) in solving the on-line Bin-Packing problem. The main idea is to show how GEP can automatically find acceptable heuristic rules to solve the problem efficiently…

神经与进化计算 · 计算机科学 2020-01-28 Najla Akram Al-Saati

One of the most powerful techniques to study protein structures is to look for recurrent fragments (also called substructures or spatial motifs), then use them as patterns to characterize the proteins under study. An emergent trend consists…

计算工程、金融与科学 · 计算机科学 2018-03-02 Wajdi Dhifli , Rabie Saidi , Engelbert Mephu Nguifo

We propose a new method for constructing elimination templates for efficient polynomial system solving of minimal problems in structure from motion, image matching, and camera tracking. We first construct a particular affine…

计算机视觉与模式识别 · 计算机科学 2022-03-29 Evgeniy Martyushev , Jana Vrablikova , Tomas Pajdla