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Clinical guidance systems have been widely adopted to help medical staffs to avoid preventable medical errors such as delay in diagnosis, treatment or untended deviations from best practice guidelines. However, because patient condition…

计算机与社会 · 计算机科学 2016-10-24 Maryam Rahmaniheris , Yu Jiang , Lui Sha

With the advancement of precision medicine there is an increasing need for design and analysis methods in clinical trials with the objective of investigating effect heterogeneity and estimating subgroup effects. As this requires precise…

统计方法学 · 统计学 2026-03-12 Shirin Golchi , Satoshi Morita

The MammoGrid project aims to deliver a prototype which enables the effective collaboration between radiologists using grid, service-orientation and database solutions. The grid technologies and service-based database management solution…

分布式、并行与集群计算 · 计算机科学 2007-05-23 Florida Estrella , Richard McClatchey , Dmitry Rogulin

To ensure fulfilling stakeholder wishes, it is crucial to validate the documented requirements. This is often complicated by the fact that the wishes and intentions of different stakeholders are somewhat contradictory, which manifests…

软件工程 · 计算机科学 2019-01-23 Marian Daun , Jennifer Brings , Thorsten Weyer

Determination of design parameters based on electromagnetic simulations of microwave circuits is an iterative and often time-consuming procedure. Space mapping is a powerful technique to optimize such complex models by efficiently…

其他计算机科学 · 计算机科学 2010-04-27 Saeed Tavakoli , Mahdieh Zeinadini , Shahram Mohanna

This paper discusses a model-based approach to testing as a vital part of software development. It argues that an approach using models as central development artifact needs to be added to the portfolio of software engineering techniques,…

软件工程 · 计算机科学 2014-09-24 Bernhard Rumpe

This work was done with the aim of developing the fundamental breast cancer early differential diagnosis foundations based on modeling the space-time temperature distribution using the microwave radiothermometry method and obtained data…

机器学习 · 计算机科学 2020-12-21 Maxim Polyakov , Illarion Popov , Alexander Losev , Alexander Khoperskov

Model-based approaches for image reconstruction, analysis and interpretation have made significant progress over the last decades. Many of these approaches are based on either mathematical, physical or biological models. A challenge for…

计算机视觉与模式识别 · 计算机科学 2019-10-01 Daniel Rueckert , Julia A. Schnabel

This paper discusses the concept of model-driven software engineering applied to the Grid application domain. As an extension to this concept, the approach described here, attempts to combine both formal architecture-centric and…

软件工程 · 计算机科学 2007-05-23 David Manset , Herve Verjus , Richard McClatchey , Flavio Oquendo

This article discusses the opportunities, applications and future directions of large-scale pre-trained models, i.e., foundation models, for analyzing medical images. Medical foundation models have immense potential in solving a wide range…

图像与视频处理 · 电气工程与系统科学 2023-11-23 Shaoting Zhang , Dimitris Metaxas

Foundation models (FMs) are changing the way medical images are analyzed by learning from large collections of unlabeled data. Instead of relying on manually annotated examples, FMs are pre-trained to learn general-purpose visual features…

Breast cancer is a major cause of cancer death among women, emphasising the importance of early detection for improved treatment outcomes and quality of life. Mammography, the primary diagnostic imaging test, poses challenges due to the…

计算机视觉与模式识别 · 计算机科学 2023-08-03 Yijun Yang , Shujun Wang , Lihao Liu , Sarah Hickman , Fiona J Gilbert , Carola-Bibiane Schönlieb , Angelica I. Aviles-Rivero

Mammography is a vital screening technique for early revealing and identification of breast cancer in order to assist to decrease mortality rate. Practical applications of mammograms are not limited to breast cancer revealing,…

图像与视频处理 · 电气工程与系统科学 2020-10-08 Aparna Bhale , Manish Joshi

Clinical management of cancer has continuously evolved for several decades. Biochemical, molecular and genomics approaches have brought and still bring numerous insights into cancerous diseases. It is now accepted that some phenomena,…

In survival analysis, traditional models assume all individuals will eventually experience the event of interest. However, advances in therapeutics have led to multiple clinical contexts with potentially curative therapies, and in these…

The designers pre-occupation to reduce energy consumption and to achieve better thermal ambience levels, has favoured the setting up of numerous building thermal dynamic simulation programs. The progress in the modelling of phenomenas and…

计算工程、金融与科学 · 计算机科学 2012-12-26 Harry Boyer , François Garde , Jean Claude Gatina , Jean Brau

Machine learning continues to emerge as an important tool to be utilised within structural engineering and structural health monitoring, due to its ability to accurately and quickly perform both regression and classification tasks. However,…

机器学习 · 计算机科学 2026-05-01 Daisy R Bradley , Elizabeth J Cross

With the increasing significance of Research, Technology, and Innovation (RTI) policies in recent years, the demand for detailed information about the performance of these sectors has surged. Many of the current tools are limited in their…

软件工程 · 计算机科学 2025-01-22 Alexandra Mazak-Huemer , Christian Huemer , Michael Vierhauser , Jürgen Janger

The goal of cancer immunotherapy is to boost a patient's immune response to a tumor. Yet, the design of an effective immunotherapy is complicated by various factors, including a potentially immunosuppressive tumor microenvironment,…

组织与器官 · 定量生物学 2017-06-29 Anna Konstorum , Anthony T. Vella , Adam J. Adler , Reinhard Laubenbacher

Artificial intelligence (AI) has been used in various areas to support system optimization and find solutions where the complexity makes it challenging to use algorithmic and heuristics. Case-based Reasoning (CBR) is an AI technique…

人工智能 · 计算机科学 2020-09-10 Eliseu M. Oliveira , Rafael F. Reale , Joberto S. B. Martins