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It has been shown that differences in fecundity variance can influence the probability of invasion of a genotype in a population, i.e. a genotype with lower variance in offspring number can be favored in finite populations even if it has a…

种群与进化 · 定量生物学 2007-05-23 Max Shpak

Genetically identical cells in the same population can take on phenotypically variable states, leading to differentiated responses to external signals, such as nutrients and drug-induced stress. Many models and experiments have focused on a…

分子网络 · 定量生物学 2015-04-28 Thierry Mora , Aleksandra M. Walczak

Population genetic studies have found evidence for dramatic population growth in recent human history. It is unclear how this recent population growth, combined with the effects of negative natural selection, has affected patterns of…

种群与进化 · 定量生物学 2014-02-11 Kirk E. Lohmueller

We study the evolution of allele frequencies in a large population where random mating is violated in a particular way that is related to recent works on speciation. Specifically, we consider non-random encounters in haploid organisms…

种群与进化 · 定量生物学 2013-09-05 David M. Schneider , Ayana B. Martins , Eduardo do Carmo , Marcus A. M. de Aguiar

Evolution occurs in populations of reproducing individuals. It is well known that population structure can affect evolutionary dynamics. Traditionally, natural selection is studied between mutants that differ in reproductive rate, but are…

种群与进化 · 定量生物学 2021-11-23 Josef Tkadlec , Kamran Kaveh , Krishnendu Chatterjee , Martin A. Nowak

We consider neutral evolution of a large population subject to changes in its population size. For a population with a time-variable carrying capacity we have computed the distributions of the total branch lengths of its sample genealogies.…

种群与进化 · 定量生物学 2012-06-13 A. Eriksson , B. Mehlig , M. Rafajlovic , S. Sagitov

When beneficial mutations are rare, they accumulate by a series of selective sweeps. But when they are common, many beneficial mutations will occur before any can fix, so there will be many different mutant lineages in the population…

种群与进化 · 定量生物学 2007-05-23 Michael M. Desai , Daniel S. Fisher

An ongoing debate in evolutionary biology is whether phenotypic change occurs predominantly around the time of speciation or whether it instead accumulates gradually over time. In this work I propose a general framework incorporating both…

种群与进化 · 定量生物学 2014-07-02 Krzysztof Bartoszek

We consider the Moran model of population genetics with two types, mutation, and selection, and investigate the line of descent of a randomly-sampled individual from a contemporary population. We trace this ancestral line back into the…

概率论 · 数学 2024-05-22 Ellen Baake , Enrico Di Gaspero , Fernando Cordero

We study the impact of a hard selective sweep on the genealogy of partially linked neutral loci in the vicinity of the positively selected allele. We consider a sexual population of stochastically varying size and, focusing on two…

概率论 · 数学 2016-05-10 Rebekka Brink-Spalink , Charline Smadi

The adaptive evolution of large asexual populations is generally characterized by competition between clones carrying different beneficial mutations. This interference phenomenon slows down the adaptation speed and makes the theoretical…

种群与进化 · 定量生物学 2012-12-20 Maria Rita Fumagalli , Matteo Osella , Philippe Thomen , Francois Heslot , Marco Cosentino Lagomarsino

We have simulated the evolution of age structured populations whose individuals represented by their diploid genomes were distributed on a square lattice. The environmental conditions on the whole territory changed simultaneously in the…

种群与进化 · 定量生物学 2009-11-05 Wojciech Waga , Marta Zawierta , Stanislaw Cebrat

We analyse the statistical properties of genealogical trees in a neutral model of a closed population with sexual reproduction and non-overlapping generations. By reconstructing the genealogy of an individual from the population evolution,…

凝聚态物理 · 物理学 2009-10-31 Bernard Derrida , Susanna C. Manrubia , Damian H. Zanette

We consider a neutral haploid population whose generations are not overlapping and whose size is large and constantly of $N$ individuals. Any generation is replaced by a new one and any individual has a single parent. We do not choose the…

种群与进化 · 定量生物学 2009-11-11 Maurizio Serva

We define a general class of models representing natural selection between two alleles. The population size and spatial structure are arbitrary, but fixed. Genetics can be haploid, diploid, or otherwise; reproduction can be asexual or…

种群与进化 · 定量生物学 2021-02-05 Benjamin Allen , Alex McAvoy

Large populations may contain numerous simultaneously segregating polymorphisms subject to natural selection. Since selection acts on individuals whose fitness depends on many loci, different loci affect each other's dynamics. This leads to…

种群与进化 · 定量生物学 2011-08-09 Richard A. Neher , Boris I. Shraiman

Within the framework of population genetics we consider the evolution of an asexual haploid population under the effect of a rapidly varying natural selection (microevolution). We focus on the case in which the environment exerting…

种群与进化 · 定量生物学 2015-06-22 Stefano Bo , Andrea Mazzolini , Antonio Celani

In large populations, multiple beneficial mutations may be simultaneously spreading. In asexual populations, these mutations must either arise on the same background or compete against each other. In sexual populations, recombination can…

种群与进化 · 定量生物学 2013-12-19 D. B. Weissman , O. Hallatschek

We consider birth-and-death stochastic evolution of genotypes with different lengths. The genotypes might mutate that provides a stochastic changing of lengthes by a free diffusion law. The birth and death rates are length dependent which…

种群与进化 · 定量生物学 2015-06-16 Dmitri Finkelshtein , Yuri Kondratiev , Oleksandr Kutoviy , Stanislav Molchanov , Elena Zhizhina

A simulation model of a population having internal (genetic) structure is presented. The population is subject to selection pressure coming from the environment which is the same in the whole system but changes in time. Reproduction has a…

适应与自组织系统 · 物理学 2012-08-31 Andrzej Pekalski , Marcel Ausloos
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