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MicroRNAs are extensively known for post-transcriptional gene regulation and pattern formation in the embryonic developmental stage. We explore the origin of these spatio-temporal patterns mathematically, considering three different motifs…

定量方法 · 定量生物学 2023-07-19 Priya Chakraborty , Sayantari Ghosh

In the framework of Anisotropic Chromo Dynamics, a non-perturbative model of QCD based on magnetic condensation in the vacuum, we develope a picture of the Pomeron. Within this model we are able to calculate the diffractive contribution to…

高能物理 - 唯象学 · 物理学 2009-10-28 L. Dick , V. Karapetian , R. Barni , G. Preparata

The development of new techniques to quantitatively measure gene expression in cells has shed light on a number of systems that display oscillations in protein concentration. Here we review the different mechanisms which can produce…

分子网络 · 定量生物学 2009-11-13 G. Tiana , S. Krishna , S. Pigolotti , M. H. Jensen , K. Sneppen

In special coordinates (codon position--specific nucleotide frequencies) bacterial genomes form two straight lines in 9-dimensional space: one line for eubacterial genomes, another for archaeal genomes. All the 348 distinct bacterial…

基因组学 · 定量生物学 2007-11-13 A. N. Gorban , A. Yu. Zinovyev

Crack formation is conventionally described as a nucleation phenomenon despite the fact that the temperatures necessary to overcome the nucleation barrier are far too high. In this paper we consider the possibility that cracks are created…

统计力学 · 物理学 2009-10-31 Peter F. Arndt , Thomas Nattermann

This work addresses the question of the interplay of DNA demixing and supercoiling in bacterial cells. Demixing of DNA from other globular macromolecules results from the overall repulsion between all components of the system and leads to…

生物物理 · 物理学 2020-08-14 Marc Joyeux

DNA-coated colloids can self-assemble into an incredible diversity of crystal structures, but applications of this technology are limited by poor understanding and control over the dynamical crystallization pathways. To address this…

软凝聚态物质 · 物理学 2021-06-01 Alexander Hensley , William M. Jacobs , W. Benjamin Rogers

The biopolymers actin and microtubules are often in an ongoing assembling/disassembling state far from thermal equilibrium. Above a critical density this leads to spatially periodic patterns, as shown by a scaling argument and in terms of a…

软凝聚态物质 · 物理学 2007-05-23 Falko Ziebert , Walter Zimmermann

Materials property predictions have improved from advances in machine learning algorithms, delivering materials discoveries and novel insights through data-driven models of structure-property relationships. Nearly all available models rely…

材料科学 · 物理学 2022-04-13 Yiqun Wang , Xiao-Jie Zhang , Fei Xia , Elsa A. Olivetti , Ram Seshadri , James M. Rondinelli

A solid-state nanopore can electrophoretically capture a DNA molecule and pull it through in a folded configuration. The resulting ionic current signal indicates where along its length the DNA was captured. A statistical study using an 8 nm…

生物物理 · 物理学 2015-06-11 Mirna Mihovilovic , Nick Hagerty , Derek Stein

Many thermodynamic instabilities in one dimension (e.g. DNA thermal denaturation, wetting of interfaces) can be described in terms of simple models involving harmonic coupling between nearest neighbors and an asymmetric on-site potential…

统计力学 · 物理学 2015-06-24 Thierry Dauxois , Nikos Theodorakopoulos , Michel Peyrard

Normal diffusion in corrugated potentials with spatially uncorrelated Gaussian energy disorder famously explains the origin of non-Arrhenius $\exp[-\sigma^2/(k_BT^2)]$ temperature-dependence in disordered systems. Here we show that unbiased…

统计力学 · 物理学 2014-09-24 Igor Goychuk , V. O. Kharchenko

In columnar assemblies of helical bio-molecules the azimuthal degrees of freedom, i.e. rotations about the long axes of molecules, may be important in determining the structure of the assemblies especially when the interaction energy…

生物物理 · 物理学 2009-11-11 D. J. Lee , A. Wynveen

The behavior of nuclear matter is studied at low densities and temperatures using classical molecular dynamics with three different sets of potentials with different compressibility. Nuclear matter is found to arrange in crystalline…

核理论 · 物理学 2013-05-13 C. O. Dorso , P. A. Giménez Molinelli , J. I. Nichols , J. A. López

The role of inhomegeneity in determining the properties of correlated electron systems is poorly understood because of the dearth of structural probes of disorder at the nanoscale. Advances in both neutron and x-ray scattering…

强关联电子 · 物理学 2025-03-19 Raymond Osborn , Damjan Pelc , Matthew Krogstad , Stephan Rosenkranz , Martin Greven

Selected theoretical developments in modeling of deposition of submicrometer size (submicron) particles on solid surfaces, with and without surface diffusion, of interest in colloid, polymer, and certain biological systems, are surveyed. We…

材料科学 · 物理学 2008-10-16 Vladimir Privman

Macromolecular crowding plays a principal role in a wide range of biological processes including gene expression, chromosomal compaction, and viral infection. However, the impact that crowding has on the dynamics of nucleic acids remains a…

DNA self-assembly is a well-understood nanotechnology to obtain extremely ordered structures from the nanometer to up to the hundred of microns scale. By contrast, DNA hydrogels rely on the disordered assembly of DNA building blocks to…

Nonuniform neutron-rich matter present in both core-collapse supernovae and neutron-star crusts is described in terms of a semiclassical model that reproduces nuclear-matter properties and includes long-range Coulomb interactions. The…

天体物理学 · 物理学 2009-11-10 C. J. Horowitz , M. A. Perez-Garcia , J. Carriere , D. K. Berry , J. Piekarewicz

There is now growing evidence of the emergence and biological functionality of liquid crystal features, including nematic order and topological defects, in cellular tissues. However, how such features that intrinsically rely on particle…

软凝聚态物质 · 物理学 2019-02-06 Romain Mueller , Julia Yeomans , Amin Doostmohammadi