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Describing and measuring the elastic properties of cellular materials such as honeycombs and foams can be a difficult problem when the cell structure is disordered. This paper suggests that tracking the flow of forces through the material…

材料科学 · 物理学 2012-03-27 Mitchell A. Berger

The effect of self-affine roughness on solid contact is examined with molecular dynamics and continuum calculations. The contact area and normal and lateral stiffnesses rise linearly with the applied load, and the load rises exponentially…

介观与纳米尺度物理 · 物理学 2015-05-20 Sreekanth Akarapu , Tristan Sharp , Mark O. Robbins

We study the elastic response of composites of rods embedded in elastic media. We calculate the micro-mechanical response functions, and bulk elastic constants as functions of rod density. We find two fixed points for Poisson's ratio with…

材料科学 · 物理学 2013-05-29 Moumita Das , F. C. MacKintosh

We propose a model for the elastic properties of RNA gels. The model predicts anomalous elastic properties in the form of a negative Poisson ratio and shape instabilities. The anomalous elasticity is generated by the non-Gaussian…

软凝聚态物质 · 物理学 2007-05-23 Amir Ahsan , Joseph Rudnick , Robijn Bruinsma

Poisson ratio is an important mechanical property that reveals the deformation patterns of materials. A positive Poisson ratio is a feature of the majority of materials. Some materials, however, display auxetic behaviors (i.e. possess…

经典物理 · 物理学 2018-02-08 S. Faroughi , M. Shaat

Living tissues experience various external forces on cells, influencing their behaviour, physiology, shape, gene expression, and destiny through interactions with their environment. Despite much research done in this area, challenges remain…

定量方法 · 定量生物学 2024-03-05 Akepogu Venkateshwarlu , Akshayveer , Sundeep Singh , Roderick Melnik

We present first-principles calculations of elastic properties of multilayered two-dimensional crystals such as graphene, h-BN and 2H-MoS2 which shows that their Poisson's ratios along out-of-plane direction are negative, near zero and…

材料科学 · 物理学 2017-01-04 Sungjong Woo , Hee Chul Park , Young-Woo Son

In glass, starting from a dependence of the Angell's fragility on the Poisson ratio [V. N. Novikov and A. P. Sokolov, Nature 431, 961 (2004)], and a dependence of the Poisson ratio on the atomic packing density [G. N. Greaves et al., Nat.…

材料科学 · 物理学 2013-08-21 Eugène Duval , Thierry Deschamps , Lucien Saviot

One of the most unique physical features of cell adhesion to external surfaces is the active generation of mechanical force at the cell-material interface. This includes pulling forces generated by contractile polymer bundles and networks,…

细胞行为 · 定量生物学 2013-09-12 Ulrich S. Schwarz , Samuel S. Safran

Tuning of active prestress e.g. through activity of molecular motors constitutes a powerful cellular tool to adjust cellular stiffness through nonlinear material properties. Understanding this tool is an important prerequisite for our…

软凝聚态物质 · 物理学 2018-08-24 Elisabeth Fischer-Friedrich

Under extensional strain, fiber networks can exhibit an anomalously large and nonlinear Poisson effect accompanied by a dramatic transverse contraction and volume reduction for applied strains as small as a few percent. We demonstrate that…

软凝聚态物质 · 物理学 2020-01-31 Jordan L. Shivers , Sadjad Arzash , Fred C. MacKintosh

The size and shape of a large variety of polymeric particles, including biological cells, star polymers, dendrimes, and microgels, depend on the applied stresses as the particles are extremely soft. In high-density suspensions these…

统计力学 · 物理学 2018-04-11 Yan-Wei Li , Massimo Pica Ciamarra

Many types of mammalian cells exert active contractile forces and mechanically deform their elastic substrate, to accomplish biological functions such as cell migration. These substrate deformations provide a mechanism by which cells can…

软凝聚态物质 · 物理学 2022-02-22 Subhaya Bose , Patrick S. Noerr , Ajay Gopinathan , Arvind Gopinath , Kinjal Dasbiswas

Animal cells are active, contractile objects. While bioassays address the molecular characterization of cell contractility, the mechanical characterization of the active forces in cells remains challenging. Here by confronting theoretical…

细胞行为 · 定量生物学 2022-09-14 Hélène Delanoë-Ayari , Nicolas Bouchonville , Marie Courçon , Alice Nicolas

The alignment of fibers and cells in living tissues affect their mechanical properties and functionality. In this context, one can draw an analogy between tissues and nematic liquid crystal elastomers. We explore this analogy by growing…

软凝聚态物质 · 物理学 2025-10-08 Kirsten Endresen , Aniruddh Murali , Birte Geerds , Daniel J. G. Pearce , Francesca Serra

Living cells are soft bodies of a characteristic form, but endowed with a capacity for a steady turnover of their structures. Both of these material properties, i.e. recovery of the shape after an external stress has been imposed and…

软凝聚态物质 · 物理学 2007-05-23 Erwin Frey , Klaus Kroy , Jan Wilhelm

The mechanical environment of a substrate plays a key role in influencing the behavior of adherent biological cells. Traditional tunable substrates have limitations as their mechanical properties cannot be dynamically altered in-situ during…

软凝聚态物质 · 物理学 2025-11-12 Manu Sebastian , Sreenath Balakrishnan , Safvan Palathingal

Elastic properties of soft, three-dimensional dimers, interacting through site-site n-inverse-power potential, are determined by computer simulations at zero temperature. The degenerate crystal of dimers exhibiting (Gaussian) size…

计算物理 · 物理学 2015-04-14 J. W. Narojczyk , K. W. Wojciechowski

Cell division and death can be regulated by the mechanical forces within a tissue. We study the consequences for the stability and roughness of a propagating interface, by analysing a model of mechanically-regulated tissue growth in the…

生物物理 · 物理学 2018-12-12 John J. Williamson , Guillaume Salbreux

The evolution of various competing cell types in tissues, and the resulting persistent tissue population, is studied numerically and analytically in a particle-based model of active tissues. Mutations change the properties of cells in…

种群与进化 · 定量生物学 2024-06-03 Tobias Büscher , Nirmalendu Ganai , Gerhard Gompper , Jens Elgeti