中文
相关论文

相关论文: Local graph alignment and motif search in biologic…

200 篇论文

One of the most important concepts in biological network analysis is that of network motifs, which are patterns of interconnections that occur in a given network at a frequency higher than expected in a random network. In this work we are…

离散数学 · 计算机科学 2020-05-29 Diego P Rubert , Eloi Araujo , Marco A Stefanes , Jens Stoye , Fábio V Martinez

Motifs are the fundamental components of complex systems. The topological structure of networks representing complex systems and the frequency and distribution of motifs in these networks are intertwined. The complexities associated with…

社会与信息网络 · 计算机科学 2020-05-21 Ali Jazayeri , Christopher C. Yang

The identification of motifs--subgraphs that appear significantly more often in a particular network than in an ensemble of randomized networks--has become a ubiquitous method for uncovering potentially important subunits within networks…

分子网络 · 定量生物学 2010-08-27 Reid Ginoza , Andrew Mugler

Studying the topology of so-called real networks, that is networks obtained from sociological or biological data for instance, has become a major field of interest in the last decade. One way to deal with it is to consider that networks are…

应用统计 · 统计学 2010-07-27 Etienne Birmele

The biological processes of cellular decision making and differentiation involve a plethora of signalling pathways and gene regulatory circuits. These networks, in their turn, exhibit a multitude of motifs playing crucial parts in…

分子网络 · 定量生物学 2018-05-02 Gustavo Rodrigues Ferreira , Helder Imoto Nakaya , Luciano da Fontoura Costa

Studying the topology of so-called {\em real networks}, that is networks obtained from sociological or biological data for instance, has become a major field of interest in the last decade. One way to deal with it is to consider that…

应用统计 · 统计学 2010-11-23 Etienne Birmele

Biomolecular networks have already found great utility in characterizing complex biological systems arising from pair-wise interactions amongst biomolecules. Here, we review how graph theoretical approaches can be applied not only for a…

分子网络 · 定量生物学 2018-12-03 Heeralal Janwa , Steven E. Massey , Julian Velev , Bud Mishra

Many real-world networks describe systems in which interactions decay with the distance between nodes. Examples include systems constrained in real space such as transportation and communication networks, as well as systems constrained in…

统计力学 · 物理学 2009-11-10 Shalev Itzkovitz , Uri Alon

This paper looks at the task of network topology inference, where the goal is to learn an unknown graph from nodal observations. One of the novelties of the approach put forth is the consideration of prior information about the density of…

信号处理 · 电气工程与系统科学 2022-07-12 Samuel Rey , T. Mitchell Roddenberry , Santiago Segarra , Antonio G. Marques

Sequence comparison and alignment has had an enormous impact on our understanding of evolution, biology, and disease. Comparison and alignment of biological networks will likely have a similar impact. Existing network alignments use…

分子网络 · 定量生物学 2009-10-08 Oleksii Kuchaiev , Tijana Milenkovic , Vesna Memisevic , Wayne Hayes , Natasa Przulj

Recent evidence indicates that the abundance of recurring elementary interaction patterns in complex networks, often called subgraphs or motifs, carry significant information about their function and overall organization. Yet, the…

无序系统与神经网络 · 物理学 2009-11-10 A. Vazquez , R. Dobrin , D. Sergi , J. -P. Eckmann , Z. N. Oltvai , A. -L. Barabasi

In the age of social computing, finding interesting network patterns or motifs is significant and critical for various areas such as decision intelligence, intrusion detection, medical diagnosis, social network analysis, fake news…

社会与信息网络 · 计算机科学 2022-04-07 Shuo Yu , Feng Xia , Yuchen Sun , Tao Tang , Xiaoran Yan , Ivan Lee

Motifs are patterns of subgraphs of complex networks. We studied the impact of such patterns of connectivity on the level of correlated, or synchronized, spiking activity among pairs of cells in a recurrent network model of integrate and…

神经元与认知 · 定量生物学 2015-06-05 Yu Hu , James Trousdale , Kresimir Josic , Eric Shea-Brown

Recent genomic and bioinformatic advances have motivated the development of numerous random network models purporting to describe graphs of biological, technological, and sociological origin. The success of a model has been evaluated by how…

Graph motif, defined as the microstructure that appears repeatedly in a large graph, reveals important topological characteristics of the large graph and has gained increasing attention in power system analysis regarding reliability,…

系统与控制 · 电气工程与系统科学 2024-12-10 Yiyan Li , Zhenghao Zhou , Jian Ping , Xiaoyuan Xu , Zheng Yan , Jianzhong Wu

Networks are a fundamental tool for modeling complex systems in a variety of domains including social and communication networks as well as biology and neuroscience. Small subgraph patterns in networks, called network motifs, are crucial to…

社会与信息网络 · 计算机科学 2018-01-08 Ashwin Paranjape , Austin R. Benson , Jure Leskovec

The mining of graphs in terms of their local substructure is a well-established methodology to analyze networks. It was hypothesized that motifs - subgraph patterns which appear significantly more often than expected at random - play a key…

社会与信息网络 · 计算机科学 2015-01-16 Marco Winkler , Joerg Reichardt

Several natural and theoretical networks can be broken down into smaller portions, or subgraphs corresponding to neighborhoods. The more frequent of these neighborhoods can then be understood as motifs of the network, being therefore…

物理与社会 · 物理学 2022-04-21 Guilherme S. Domingues , Eric K. Tokuda , Luciano da F. Costa

Network science can offer fundamental insights into the structural and functional properties of complex systems. For example, it is widely known that neuronal circuits tend to organize into basic functional topological modules, called…

适应与自组织系统 · 物理学 2022-08-03 Matteo Zambra , Alberto Testolin , Amos Maritan

A deluge of new data on social, technological and biological networked systems suggests that a large number of interactions among system units are not limited to pairs, but rather involve a higher number of nodes. To properly encode such…

‹ 上一页 1 2 3 10 下一页 ›