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Estimating brain age (BA) from T1-weighted magnetic resonance images (MRIs) provides a powerful framework for quantifying anatomical brain aging. Whereas global BA (GBA) summarizes overall brain health, local BA (LBA) provides cortically…

One fascinating aspect of the brain is its ability to process information in a fast and reliable manner. The functional architecture is thought to play a central role in this task, by encoding efficiently complex stimuli and facilitating…

神经元与认知 · 定量生物学 2016-02-17 Alberto Romagnoni , Jérôme Ribot , Daniel Bennequin , Jonathan D. Touboul

In the deep metric learning approach to image segmentation, a convolutional net densely generates feature vectors at the pixels of an image. Pairs of feature vectors are trained to be similar or different, depending on whether the…

计算机视觉与模式识别 · 计算机科学 2019-02-04 Kyle Luther , H. Sebastian Seung

Mathematical morphology (MM) helps to describe and analyze shapes using set theory. MM can be effectively applied to binary images which are treated as sets. Basic morphological operators defined can be used as an effective tool in image…

计算机视觉与模式识别 · 计算机科学 2015-07-28 Keerthana S. Prakash , R. P. Prakash , V. P. Binu

Different cell types aggregate and sort into hierarchical architectures during the formation of animal tissues. The resulting spatial organization depends (in part) on the strength of adhesion of one cell type to itself relative to other…

定量方法 · 定量生物学 2023-08-02 Dhananjay Bhaskar , William Y. Zhang , Alexandria Volkening , Björn Sandstede , Ian Y. Wong

In Functional Data Analysis, data are commonly assumed to be smooth functions on a fixed interval of the real line. In this work, we introduce a comprehensive framework for the analysis of functional data, whose domain is a two-dimensional…

统计方法学 · 统计学 2019-08-02 Eardi Lila , John A. D. Aston

Topology optimization of microstructures plays a critical role in optimizing functional performance across diverse engineering applications. While metamaterials with enhanced mechanical properties -- such as hyperelasticity, energy…

软凝聚态物质 · 物理学 2025-01-27 Weiming Wang , Yanhao Hou , Renbo Su , Weiguang Wang , Charlie C. L. Wang

Recent advances in propagation-based phase-contrast imaging, such as hierarchical imaging, have enabled the visualization of internal structures in large biological specimens and material samples. However, modulation-based techniques, which…

To understand the biological characteristics of neurological disorders with functional connectivity (FC), recent studies have widely utilized deep learning-based models to identify the disease and conducted post-hoc analyses via explainable…

机器学习 · 计算机科学 2023-10-09 Eunsong Kang , Da-woon Heo , Jiwon Lee , Heung-Il Suk

Deep learning has revolutionized medical and biological imaging, particularly in segmentation tasks. However, segmenting biological cells remains challenging due to the high variability and complexity of cell shapes. Addressing this…

计算机视觉与模式识别 · 计算机科学 2025-06-03 Tianhao Zhang , Heather J. McCourty , Berardo M. Sanchez-Tafolla , Anton Nikolaev , Lyudmila S. Mihaylova

We propose a 3D convolutional neural network to simultaneously segment and detect cell nuclei in confocal microscopy images. Mirroring the co-dependency of these tasks, our proposed model consists of two serial components: the first part…

图像与视频处理 · 电气工程与系统科学 2018-09-07 Sundaresh Ram , Vicky T. Nguyen , Kirsten H. Limesand , Mert R. Sabuncu

The Allen Brain Atlas (ABA) of the adult mouse consists of digitized expression profiles of thousands of genes in the mouse brain, co-registered to a common three-dimensional template (the Allen Reference Atlas). This brain-wide,…

神经元与认知 · 定量生物学 2015-10-28 Pascal Grange

Human action recognition from skeletal data is a hot research topic and important in many open domain applications of computer vision, thanks to recently introduced 3D sensors. In the literature, naive methods simply transfer off-the-shelf…

计算机视觉与模式识别 · 计算机科学 2017-08-04 Jacopo Cavazza , Pietro Morerio , Vittorio Murino

The science of fractography revolves around the correlation between topographic characteristics of the fracture surface and the mechanisms and external conditions leading to their creation. While being a topic of investigation for…

图像与视频处理 · 电气工程与系统科学 2020-05-11 Stylianos Tsopanidis , Raúl Herrero Moreno , Shmuel Osovski

The hippocampus is one of the most studied neuroanatomical structures due to its involvement in attention, learning, and memory as well as its atrophy in ageing, neurological, and psychiatric diseases. Hippocampal shape changes, however,…

计算机视觉与模式识别 · 计算机科学 2023-06-13 Kersten Diers , Hannah Baumeister , Frank Jessen , Emrah Düzel , David Berron , Martin Reuter

Identifying cerebral cortex layers is crucial for comparative studies of the cytoarchitecture aiming at providing insights into the relations between brain structure and function across species. The absence of extensive annotated datasets…

计算机视觉与模式识别 · 计算机科学 2023-11-28 Valentina Vadori , Antonella Peruffo , Jean-Marie Graïc , Giulia Vadori , Livio Finos , Enrico Grisan

Identification and counting of cells and mitotic figures is a standard task in diagnostic histopathology. Due to the large overall cell count on histological slides and the potential sparse prevalence of some relevant cell types or mitotic…

计算机视觉与模式识别 · 计算机科学 2017-09-08 Marc Aubreville , Maximilian Krappmann , Christof Bertram , Robert Klopfleisch , Andreas Maier

In this work, the Minkowski functionals are used as a framework to study how morphology (i.e. the shape of a structure) and topology (i.e. how different structures are connected) influence wall adsorption and capillary condensation under…

软凝聚态物质 · 物理学 2021-08-11 Arnout M P Boelens , Hamdi A Tchelepi

This work proposes and study the concept of Functional Data Analysis transform, applying it to the performance improving of volumetric Bouligand-Minkowski fractal descriptors. The proposed transform consists essentially in changing the…

计算机视觉与模式识别 · 计算机科学 2012-01-17 João Batista Florindo , Mário de Castro , Odemir Martinez Bruno

It is important to extract good features using an encoder to realize semantic segmentation with high accuracy. Although loss function is optimized in training deep neural network, far layers from the layers for computing loss function are…

图像与视频处理 · 电气工程与系统科学 2021-01-21 Takamasa Ando , Kazuhiro Hotta