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Clinical trials provide essential guidance for practicing Evidence-Based Medicine, though often accompanying with unendurable costs and risks. To optimize the design of clinical trials, we introduce a novel Clinical Trial Result Prediction…

计算与语言 · 计算机科学 2020-10-13 Qiao Jin , Chuanqi Tan , Mosha Chen , Xiaozhong Liu , Songfang Huang

Reasoning benchmarks measure clinical performance on clean inputs. We evaluate the step before reasoning: retrieval over real EHR notes, where negation, temporality, and family-versus-patient attribution can flip a correct answer to a wrong…

计算与语言 · 计算机科学 2026-05-13 Alex Stinard

Bridging clinical diagnostic reasoning with AI remains a central challenge in medical imaging. We introduce MedCLM, an automated pipeline that converts detection datasets into large-scale medical visual question answering (VQA) data with…

计算机视觉与模式识别 · 计算机科学 2025-10-07 Soo Yong Kim , Suin Cho , Vincent-Daniel Yun , Gyeongyeon Hwang

Large language models (LLMs) have shown considerable potential in supporting medical diagnosis. However, their effective integration into clinical workflows is hindered by physicians' difficulties in perceiving and trusting LLM…

人机交互 · 计算机科学 2026-01-28 Yuansong Xu , Yichao Zhu , Haokai Wang , Yuchen Wu , Yang Ouyang , Hanlu Li , Wenzhe Zhou , Xinyu Liu , Chang Jiang , Quan Li

Existing multi-behavior recommendations tend to prioritize performance at the expense of explainability, while current explainable methods suffer from limited generalizability due to their reliance on external information. Neuro-Symbolic…

人工智能 · 计算机科学 2026-01-30 Yuzhe Chen , Jie Cao , Youquan Wang , Haicheng Tao , Darko B. Vukovic , Jia Wu

Language models (LMs), including large language models (such as ChatGPT), have the potential to assist clinicians in generating various clinical notes. However, LMs are prone to produce ``hallucinations'', i.e., generated content that is…

计算与语言 · 计算机科学 2024-07-23 Fenglin Liu , Bang Yang , Chenyu You , Xian Wu , Shen Ge , Zhangdaihong Liu , Xu Sun , Yang Yang , David A. Clifton

Large language models (LLMs), including zero-shot and few-shot paradigms, have shown promising capabilities in clinical text generation. However, real-world applications face two key challenges: (1) patient data is highly unstructured,…

计算与语言 · 计算机科学 2025-07-10 Garapati Keerthana , Manik Gupta

Large Language Models (LLMs) are increasingly positioned as decision engines for hiring, healthcare, and economic judgment, yet real-world human judgment reflects a balance between rational deliberation and emotion-driven bias. If LLMs are…

We present Clinical Prediction with Large Language Models (CPLLM), a method that involves fine-tuning a pre-trained Large Language Model (LLM) for clinical disease and readmission prediction. We utilized quantization and fine-tuned the LLM…

计算与语言 · 计算机科学 2024-05-03 Ofir Ben Shoham , Nadav Rappoport

Large Language Models (LLMs) increasingly show reasoning rationales alongside their answers, turning "reasoning" into a user-interface element. While step-by-step rationales are typically associated with model performance, how they…

人机交互 · 计算机科学 2026-03-10 Xin Sun , Shu Wei , Jos A Bosch , Isao Echizen , Saku Sugawara , Abdallah El Ali

Deep learning-based medical image analysis faces a significant barrier due to the lack of interpretability. Conventional explainable AI (XAI) techniques, such as Grad-CAM and SHAP, often highlight regions outside clinical interests. To…

图像与视频处理 · 电气工程与系统科学 2025-02-17 Yuhao Zhang , Mingcheng Zhu , Zhiyao Luo

We present MedXIAOHE, a medical vision-language foundation model designed to advance general-purpose medical understanding and reasoning in real-world clinical applications. MedXIAOHE achieves state-of-the-art performance across diverse…

In high-stakes domains such as healthcare and finance, effective decision-making demands not just accurate outcomes but transparent and explainable reasoning. However, current language models often lack the structured deliberation needed…

计算与语言 · 计算机科学 2025-08-26 Xiusi Chen , Shanyong Wang , Cheng Qian , Hongru Wang , Peixuan Han , Heng Ji

Many existing models for clinical trial outcome prediction are optimized using task-specific loss functions on trial phase-specific data. While this scheme may boost prediction for common diseases and drugs, it can hinder learning of…

机器学习 · 计算机科学 2025-05-27 Yiqing Zhang , Xiaozhong Liu , Fabricio Murai

Computational cognitive models, which formalize theories of cognition, enable researchers to quantify cognitive processes and arbitrate between competing theories by fitting models to behavioral data. Traditionally, these models are…

机器学习 · 计算机科学 2025-11-10 Milena Rmus , Akshay K. Jagadish , Marvin Mathony , Tobias Ludwig , Eric Schulz

Effective clinical history taking is a foundational yet underexplored component of clinical reasoning. While large language models (LLMs) have shown promise on static benchmarks, they often fall short in dynamic, multi-turn diagnostic…

计算与语言 · 计算机科学 2026-01-30 Yang Zhou , Zhenting Sheng , Mingrui Tan , Yuting Song , Jun Zhou , Yu Heng Kwan , Lian Leng Low , Yang Bai , Yong Liu

Large language models (LLMs) have demonstrated impressive capabilities in natural language understanding and generation, but the quality bar for medical and clinical applications is high. Today, attempts to assess models' clinical knowledge…

We present a novel approach to neural code generation that incorporates real-time execution signals into the language model generation process. While large language models (LLMs) have demonstrated impressive code generation capabilities,…

机器学习 · 计算机科学 2025-10-24 Boaz Lavon , Shahar Katz , Lior Wolf

Explainable recommendation systems leverage transparent reasoning to foster user trust and improve decision-making processes. Current approaches typically decouple recommendation generation from explanation creation, violating causal…

人工智能 · 计算机科学 2025-03-12 Guanrong Li , Haolin Yang , Xinyu Liu , Zhen Wu , Xinyu Dai

With the continuous advancement of reasoning abilities in Large Language Models (LLMs), their application to scientific reasoning tasks has gained significant research attention. Current research primarily emphasizes boosting LLMs'…

人工智能 · 计算机科学 2026-05-19 Zhaoxin Yu , Nan Xu , Kun Chen , Jiahao Zhao , Lei Wang , Wenji Mao