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Auto-regressive LLM-based software engineering (SWE) agents, henceforth SWE agents, have made tremendous progress (>60% on SWE-Bench Verified) on real-world coding challenges including GitHub issue resolution. SWE agents use a combination…

软件工程 · 计算机科学 2025-04-15 Timothy Bula , Saurabh Pujar , Luca Buratti , Mihaela Bornea , Avirup Sil

Multimodal Large Language Models are increasingly applied to biomedical imaging, yet scientific reasoning for microscopy remains limited by the scarcity of large-scale, high-quality training data. We introduce MicroVQA++, a three-stage,…

计算机视觉与模式识别 · 计算机科学 2025-11-17 Manyu Li , Ruian He , Chenxi Ma , Weimin Tan , Bo Yan

Advances in large language models (LLMs) have encouraged their adoption in the healthcare domain where vital clinical information is often contained in unstructured notes. Cancer staging status is available in clinical reports, but it…

计算与语言 · 计算机科学 2024-08-30 Chia-Hsuan Chang , Mary M. Lucas , Yeawon Lee , Christopher C. Yang , Grace Lu-Yao

Existing LLM agents for computational materials science are constrained by pipeline-bounded architectures tied to specific simulation codes and by dependence on manually written tool functions that grow with task scope. We present MatClaw,…

材料科学 · 物理学 2026-05-25 Chenmu Zhang , Boris I. Yakobson

The emerging area of computational pathology (CPath) is ripe ground for the application of deep learning (DL) methods to healthcare due to the sheer volume of raw pixel data in whole-slide images (WSIs) of cancerous tissue slides. However,…

图像与视频处理 · 电气工程与系统科学 2020-04-23 Jevgenij Gamper , Navid Alemi Koohbanani , Ksenija Benes , Simon Graham , Mostafa Jahanifar , Syed Ali Khurram , Ayesha Azam , Katherine Hewitt , Nasir Rajpoot

Despite the growing adoption of electronic health records, many processes still rely on paper documents, reflecting the heterogeneous real-world conditions in which healthcare is delivered. The manual transcription process is time-consuming…

Liver diseases pose a significant global health burden, impacting many individuals and having substantial economic and social consequences. Rising liver problems are considered a fatal disease in many countries, such as Egypt and Moldova.…

人工智能 · 计算机科学 2025-03-21 Ritesh Chandra , Sadhana Tiwari , Satyam Rastogi , Sonali Agarwal

Evaluating AI agents that solve real-world tasks through function-call sequences remains an open challenge. Existing agentic benchmarks often reduce evaluation to a binary judgment of the final state, overlooking critical aspects such as…

人工智能 · 计算机科学 2025-09-26 Panagiotis Michelakis , Yiannis Hadjiyiannis , Dimitrios Stamoulis

Progress in biomedical Named Entity Recognition (NER) and Entity Linking (EL) is currently hindered by a fragmented data landscape, a lack of resources for building explainable models, and the limitations of semantically-blind evaluation…

计算与语言 · 计算机科学 2025-11-17 Nishant Mishra , Wilker Aziz , Iacer Calixto

Background: Cancers are highly heterogeneous with different subtypes. These subtypes often possess different genetic variants, present different pathological phenotypes, and most importantly, show various clinical outcomes such as varied…

图形学 · 计算机科学 2014-07-09 Hao Ding , Chao Wang , Kun Huang , Raghu Machiraju

In this study, we built an end-to-end tumor-infiltrating lymphocytes (TILs) assessment pipeline within QuPath, demonstrating the potential of easily accessible tools to perform complex tasks in a fully automatic fashion. First, we trained a…

The pathogenesis of cancer in human is still poorly understood. With the rapid development of high-throughput sequencing technologies, huge volumes of cancer genomics data have been generated. Deciphering those data poses great…

基因组学 · 定量生物学 2016-04-06 Junhua Zhang , Shihua Zhang

The histopathological analysis of whole-slide images (WSIs) is fundamental to cancer diagnosis but is a time-consuming and expert-driven process. While deep learning methods show promising results, dominant patch-based methods artificially…

图像与视频处理 · 电气工程与系统科学 2025-10-08 Alexander Weers , Alexander H. Berger , Laurin Lux , Peter Schüffler , Daniel Rueckert , Johannes C. Paetzold

Motivation: Multi-omics integration can improve cancer subtyping, but modality informativeness and noise vary across cancer types and patients. Existing graph-based methods optimize modality weights jointly with the classification objective…

机器学习 · 计算机科学 2026-04-28 Boyang Fan , Hengchuang Yin , Siyu Yi , Yifan Wang , Zhicheng Li , Leijiyu Zhou , Jiancheng Lv , Wei Ju

We introduce WordScape, a novel pipeline for the creation of cross-disciplinary, multilingual corpora comprising millions of pages with annotations for document layout detection. Relating visual and textual items on document pages has…

Knowledge Graph Question Answering (KGQA) aims to answer user questions by reasoning over Knowledge Graphs (KGs). Recent KGQA methods mainly follow the retrieval-augmented generation paradigm to ground Large Language Models~(LLMs) with…

人工智能 · 计算机科学 2026-05-12 Shengxiang Gao , Chao Lei , Jey Han Lau , Jianzhong Qi

With their high information density and intuitive readability, charts have become the de facto medium for data analysis and communication across disciplines. Recent multimodal large language models (MLLMs) have made notable progress in…

计算机视觉与模式识别 · 计算机科学 2025-12-17 Boran Wang , Xinming Wang , Yi Chen , Xiang Li , Jian Xu , Jing Yuan , Chenglin Liu

In Computational Pathology (CPath), the introduction of Vision-Language Models (VLMs) has opened new avenues for research, focusing primarily on aligning image-text pairs at a single magnification level. However, this approach might not be…

Accurate diagnosis of ocular surface diseases is critical in optometry and ophthalmology, which hinge on integrating clinical data sources (e.g., meibography imaging and clinical metadata). Traditional human assessments lack precision in…

计算与语言 · 计算机科学 2024-10-02 Chun-Hsiao Yeh , Jiayun Wang , Andrew D. Graham , Andrea J. Liu , Bo Tan , Yubei Chen , Yi Ma , Meng C. Lin

Machine learning and Large language models (LLMs) for vulnerability detection has received significant attention in recent years. Unfortunately, state-of-the-art techniques show that LLMs are unsuccessful in even distinguishing the…

密码学与安全 · 计算机科学 2025-08-05 Mohammed Sayagh , Mohammad Ghafari