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The development of computational pathology lies in the consensus that pathological characteristics of tumors are significant guidance for cancer diagnostics. Most existing research focuses on the inner-contextual information within each WSI…

计算机视觉与模式识别 · 计算机科学 2024-10-15 Jun Shi , Tong Shu , Zhiguo Jiang , Wei Wang , Haibo Wu , Yushan Zheng

Statistical shape modeling (SSM) characterizes anatomical variations in a population of shapes generated from medical images. SSM requires consistent shape representation across samples in shape cohort. Establishing this representation…

计算机视觉与模式识别 · 计算机科学 2022-03-17 Riddhish Bhalodia , Shireen Elhabian , Jadie Adams , Wenzheng Tao , Ladislav Kavan , Ross Whitaker

The Segment Anything Model (SAM) exhibits a capability to segment a wide array of objects in natural images, serving as a versatile perceptual tool for various downstream image segmentation tasks. In contrast, medical image segmentation…

计算机视觉与模式识别 · 计算机科学 2023-08-29 Yizhe Zhang , Tao Zhou , Shuo Wang , Ye Wu , Pengfei Gu , Danny Z. Chen

Computational pathology demands both visual pattern recognition and dynamic integration of structured domain knowledge, including taxonomy, grading criteria, and clinical evidence. In practice, diagnostic reasoning requires linking…

The Vision Foundation Model has recently gained attention in medical image analysis. Its zero-shot learning capabilities accelerate AI deployment and enhance the generalizability of clinical applications. However, segmenting pathological…

计算机视觉与模式识别 · 计算机科学 2024-07-16 Can Cui , Ruining Deng , Junlin Guo , Quan Liu , Tianyuan Yao , Haichun Yang , Yuankai Huo

Rapid progress in vision-language modeling has enabled pathology report generation from gigapixel whole-slide images, but most approaches assume static training with simultaneous access to all data. In clinical deployment, however, new…

计算机视觉与模式识别 · 计算机科学 2026-03-02 Pratibha Kumari , Daniel Reisenbüchler , Afshin Bozorgpour , yousef Sadegheih , Priyankar Choudhary , Dorit Merhof

Integrating whole-slide images (WSIs) and bulk transcriptomics for predicting patient survival can improve our understanding of patient prognosis. However, this multimodal task is particularly challenging due to the different nature of…

计算机视觉与模式识别 · 计算机科学 2024-04-16 Guillaume Jaume , Anurag Vaidya , Richard Chen , Drew Williamson , Paul Liang , Faisal Mahmood

Foundation models have recently achieved impressive success in computational pathology, demonstrating strong generalization across diverse histopathology tasks. However, existing models overlook the heterogeneous and non-uniform…

Structural Health Monitoring (SHM) is a critical task for ensuring the safety and reliability of civil infrastructures, typically realized on bridges and viaducts by means of vibration monitoring. In this paper, we propose for the first…

In Computational Pathology (CPath), the introduction of Vision-Language Models (VLMs) has opened new avenues for research, focusing primarily on aligning image-text pairs at a single magnification level. However, this approach might not be…

Spatial connectivity is an important consideration when modelling infectious disease data across a geographical region. Connectivity can arise for many reasons, including shared characteristics between regions, and human or vector movement.…

统计方法学 · 统计学 2022-06-06 Sophie A Lee , Theodoros Economou , Rachel Lowe

Traditional whole slide image (WSI) analysis methods typically rely on the multiple instance learning (MIL) paradigm, which extracts patch-level features at high magnification and aggregates them for slide-level prediction. However, such…

Recent advancements in multimodal pre-training models have significantly advanced computational pathology. However, current approaches predominantly rely on visual-language models, which may impose limitations from a molecular perspective…

计算机视觉与模式识别 · 计算机科学 2024-12-03 Minghao Han , Dingkang Yang , Jiabei Cheng , Xukun Zhang , Linhao Qu , Zizhi Chen , Lihua Zhang

Diagnosing and treating skin diseases require advanced visual skills across domains and the ability to synthesize information from multiple imaging modalities. While current deep learning models excel at specific tasks like skin cancer…

Whole-slide image (WSI) classification in computational pathology is commonly formulated as slide-level Multiple Instance Learning (MIL) with a single global bag representation. However, slide-level MIL is fundamentally underconstrained:…

Whole slide images (WSIs) are massive digital pathology files illustrating intricate tissue structures. Selecting a small, representative subset of patches from each WSI is essential yet challenging. Therefore, following the "Divide &…

计算机视觉与模式识别 · 计算机科学 2023-11-17 Abubakr Shafique , Saghir Alfasly , Areej Alsaafin , Peyman Nejat , Jibran A. Khan , H. R. Tizhoosh

Spatial proteomics maps protein distributions in tissues, providing transformative insights for life sciences. However, current sequencing-based technologies suffer from low spatial resolution, and substantial inter-tissue variability in…

定量方法 · 定量生物学 2025-08-26 Bokai Zhao , Weiyang Shi , Hanqing Chao , Zijiang Yang , Yiyang Zhang , Ming Song , Tianzi Jiang

Due to the increasing workload of pathologists, the need for automation to support diagnostic tasks and quantitative biomarker evaluation is becoming more and more apparent. Foundation models have the potential to improve generalizability…

图像与视频处理 · 电气工程与系统科学 2025-01-13 Till Nicke , Jan Raphael Schaefer , Henning Hoefener , Friedrich Feuerhake , Dorit Merhof , Fabian Kiessling , Johannes Lotz

The interpretation of small tiles in large whole slide images (WSI) often needs a larger image context. We introduce TICON, a transformer-based tile representation contextualizer that produces rich, contextualized embeddings for ''any''…

Automated building facade inspection is a critical component of urban resilience and smart city maintenance. Traditionally, this field has relied on specialized discriminative models (e.g., YOLO, Mask R-CNN) that excel at pixel-level…

计算机视觉与模式识别 · 计算机科学 2026-03-23 Hui Zhong , Yichun Gao , Luyan Liu , Hai Yang , Wang Wang , Haowei Zhang , Xinhu Zheng