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Alzheimer's Disease Analysis Model (ADAM) is a multi-agent reasoning large language model (LLM) framework designed to integrate and analyze multimodal data, including microbiome profiles, clinical datasets, and external knowledge bases, to…

Artificial intelligence (AI) systems accelerate medical workflows and improve diagnostic accuracy in healthcare, serving as second-opinion systems. However, the unpredictability of AI errors poses a significant challenge, particularly in…

Artificial intelligence (AI) in medical device software (MDSW) represents a transformative clinical technology, attracting increasing attention within both the medical community and the regulators. In this study, we leverage a data-driven…

人工智能 · 计算机科学 2026-04-27 Yu Han , Aaron Ceross , Sarim Ather , Jeroen H. M. Bergmann

Recent proposals for regulating frontier AI models have sparked concerns about the cost of safety regulation, and most such regulations have been shelved due to the safety-innovation tradeoff. This paper argues for an alternative regulatory…

人工智能 · 计算机科学 2025-10-17 Shriyash Upadhyay , Chaithanya Bandi , Narmeen Oozeer , Philip Quirke

Artificial intelligence (AI) is increasingly being utilized to optimize magnetic resonance imaging (MRI) protocols. Given that image details are critical for diagnostic accuracy, optimizing MRI acquisition protocols is essential for…

This review introduces the transformative potential of generative Artificial Intelligence (AI) and foundation models, including large language models (LLMs), for health technology assessment (HTA). We explore their applications in four…

机器学习 · 计算机科学 2024-09-24 Rachael Fleurence , Jiang Bian , Xiaoyan Wang , Hua Xu , Dalia Dawoud , Mitch Higashi , Jagpreet Chhatwal

Background: Advanced adaptive randomised clinical trials are increasingly used. Compared to their conventional counterparts, their flexibility may make them more efficient, increase the probability of obtaining conclusive results without…

Artificial Intelligence (AI) has become an important part of our everyday lives, yet user requirements for designing AI-assisted systems in law enforcement remain unclear. To address this gap, we conducted qualitative research on…

In the software industry, artificial intelligence (AI) has been utilized more and more in software development activities. In some activities, such as coding, AI has already been an everyday tool, but in software testing activities AI it…

软件工程 · 计算机科学 2025-04-08 Katja Karhu , Jussi Kasurinen , Kari Smolander

The increased capabilities of generative AI have dramatically expanded its possible use cases in medicine. We provide a comprehensive overview of generative AI use cases for clinicians, patients, clinical trial organizers, researchers, and…

机器学习 · 计算机科学 2024-12-18 Divya Shanmugam , Monica Agrawal , Rajiv Movva , Irene Y. Chen , Marzyeh Ghassemi , Maia Jacobs , Emma Pierson

Artificial intelligence (AI) has evolved considerably in the last few years. While applications of AI is now becoming more common in fields like retail and marketing, application of AI in solving problems related to developing countries is…

机器学习 · 计算机科学 2019-10-23 Anusua Trivedi , Sumit Mukherjee , Edmund Tse , Anne Ewing , Juan Lavista Ferres

There has been a surge of interest in leveraging speech as a marker of health for a wide spectrum of conditions. The underlying premise is that any neurological, mental, or physical deficits that impact speech production can be objectively…

音频与语音处理 · 电气工程与系统科学 2024-10-30 Si-Ioi Ng , Lingfeng Xu , Ingo Siegert , Nicholas Cummins , Nina R. Benway , Julie Liss , Visar Berisha

This paper systematically reviews recent advances in artificial intelligence (AI), with a particular focus on machine learning (ML), across the entire drug discovery pipeline. Due to the inherent complexity, escalating costs, prolonged…

In recent years Artificial Intelligence (AI) has gained much popularity, with the scientific community as well as with the public. AI is often ascribed many positive impacts for different social domains such as medicine and the economy. On…

计算机与社会 · 计算机科学 2021-02-01 Kimon Kieslich , Marco Lünich , Frank Marcinkowski

Phase II dose finding studies in clinical drug development are typically conducted to adequately characterize the dose response relationship of a new drug. An important decision is then on the choice of a suitable dose response function to…

应用统计 · 统计学 2015-08-04 Kirsten Schorning , Björn Bornkamp , Frank Bretz , Holger Dette

Artificial intelligence (AI) has revolutionized decision-making processes and systems throughout society and, in particular, has emerged as a significant technology in high-impact scenarios of national interest. Yet, despite AI's impressive…

机器学习 · 统计学 2024-08-05 Gregory Canal , Vladimir Leung , Philip Sage , Eric Heim , I-Jeng Wang

Artificial intelligence (AI) is increasingly integrated into modern healthcare, offering powerful support for clinical decision-making. However, in real-world settings, AI systems may experience performance degradation over time, due to…

人工智能 · 计算机科学 2026-02-05 Hao Guan , David Bates , Li Zhou

Bayesian statistics plays a pivotal role in advancing medical science by enabling healthcare companies, regulators, and stakeholders to assess the safety and efficacy of new treatments, interventions, and medical procedures. The Bayesian…

应用统计 · 统计学 2023-12-04 Se Yoon Lee

AI systems have found a wide range of application areas in financial services. Their involvement in broader and increasingly critical decisions has escalated the need for compliance and effective model governance. Current governance…

机器学习 · 计算机科学 2020-10-13 Eren Kurshan , Hongda Shen , Jiahao Chen

Artificial intelligence (AI) has been advancing at a fast pace and it is now poised for deployment in a wide range of applications, such as autonomous systems, medical diagnosis and natural language processing. Early adoption of AI…

机器学习 · 计算机科学 2023-09-21 Marta Kwiatkowska , Xiyue Zhang