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We describe a new approach to estimating relative risks in time-to-event prediction problems with censored data in a fully parametric manner. Our approach does not require making strong assumptions of constant proportional hazard of the…

机器学习 · 计算机科学 2021-06-10 Chirag Nagpal , Xinyu Rachel Li , Artur Dubrawski

Concept-based learning enhances prediction accuracy and interpretability by leveraging high-level, human-understandable concepts. However, existing CBL frameworks do not address survival analysis tasks, which involve predicting event times…

机器学习 · 计算机科学 2025-02-11 Stanislav R. Kirpichenko , Lev V. Utkin , Andrei V. Konstantinov , Natalya M. Verbova

Although the Cox proportional hazards model is well established and extensively used in the analysis of survival data, the proportional hazards (PH) assumption may not always hold in practical scenarios. The class of semiparametric…

统计方法学 · 统计学 2025-10-21 Junkai Yin , Yue Zhang , Zhangsheng Yu

Predicting counterfactual outcomes in longitudinal data, where sequential treatment decisions heavily depend on evolving patient states, is critical yet notoriously challenging due to complex time-dependent confounding and inadequate…

机器学习 · 统计学 2026-04-15 Farbod Alinezhad , Jianfei Cao , Gary J. Young , Brady Post

Censoring is the central problem in survival analysis where either the time-to-event (for instance, death), or the time-tocensoring (such as loss of follow-up) is observed for each sample. The majority of existing machine learning-based…

机器学习 · 统计学 2024-07-22 Weijia Zhang , Chun Kai Ling , Xuanhui Zhang

Diffusion models are increasingly being utilised to create synthetic tabular and time series data for privacy-preserving augmentation. Tabular Denoising Diffusion Probabilistic Models (TabDDPM) generate high-quality synthetic data from…

机器学习 · 计算机科学 2026-04-08 Umang Dobhal , Christina Garcia , Sozo Inoue

The limitations resulting from the dichtomisation of continuous outcomes have been extensively described. But the need to present results based on binary outcomes in particular in health science remains. Alternatives based on the…

统计方法学 · 统计学 2025-01-15 Odile Sauzet

Although the independent censoring assumption is commonly used in survival analysis, it can be violated when the censoring time is related to the survival time, which often happens in many practical applications. To address this issue, we…

统计方法学 · 统计学 2024-08-28 Huazhen Yu , Lixin Zhang

Survival analysis is a widely-used technique for analyzing time-to-event data in the presence of censoring. In recent years, numerous survival analysis methods have emerged which scale to large datasets and relax traditional assumptions…

机器学习 · 计算机科学 2023-11-06 Mert Ketenci , Shreyas Bhave , Noémie Elhadad , Adler Perotte

While tabular foundation models have achieved remarkable success in classification and regression, adapting them to model time-to-event outcomes for survival analysis is non-trivial due to right-censoring, where data observations may end…

机器学习 · 计算机科学 2026-02-02 Da In Kim , Wei Siang Lai , Kelly W. Zhang

Survival analysis provides a powerful statistical framework for modeling time-to-event outcomes in the presence of censoring. However, selecting an appropriate estimator from the many specialized survival approaches often requires…

机器学习 · 计算机科学 2026-05-18 Shi-ang Qi , Vahid Balazadeh , Michael Cooper , Russell Greiner , Rahul G. Krishnan

The abundance of modern health data provides many opportunities for the use of machine learning techniques to build better statistical models to improve clinical decision making. Predicting time-to-event distributions, also known as…

机器学习 · 统计学 2020-12-15 Zidi Xiu , Chenyang Tao , Benjamin A. Goldstein , Ricardo Henao

Precipitation nowcasting is a critical spatio-temporal prediction task for society to prevent severe damage owing to extreme weather events. Despite the advances in this field, the complex and stochastic nature of this task still poses…

机器学习 · 计算机科学 2025-12-25 Shi Quan Foo , Chi-Ho Wong , Zhihan Gao , Dit-Yan Yeung , Ka-Hing Wong , Wai-Kin Wong

We propose a deep generative approach to nonparametric estimation of conditional survival and hazard functions with right-censored data. The key idea of the proposed method is to first learn a conditional generator for the joint conditional…

统计理论 · 数学 2022-05-20 Xingyu Zhou , Wen Su , Changyu Liu , Yuling Jiao , Xingqiu Zhao , Jian Huang

The conditional survival function of a time-to-event outcome subject to censoring and truncation is a common target of estimation in survival analysis. This parameter may be of scientific interest and also often appears as a nuisance in…

统计方法学 · 统计学 2024-08-20 Charles J. Wolock , Peter B. Gilbert , Noah Simon , Marco Carone

Survival regression aims to predict the time when an event of interest will take place, typically a death or a failure. A fully parametric method [18] is proposed to estimate the survival function as a mixture of individual parametric…

机器学习 · 计算机科学 2024-04-25 Qinxin Wang , Jiayuan Huang , Junhui Li , Jiaming Liu

This paper introduces the Single-Cell Perturbation Prediction Diffusion Model (scPPDM), the first diffusion-based framework for single-cell drug-response prediction from scRNA-seq data. scPPDM couples two condition channels,…

定量方法 · 定量生物学 2025-10-15 Zhaokang Liang , Shuyang Zhuang , Xiaoran Jiao , Weian Mao , Hao Chen , Chunhua Shen

Survival analysis, or time-to-event modelling, is a classical statistical problem that has garnered a lot of interest for its practical use in epidemiology, demographics or actuarial sciences. Recent advances on the subject from the point…

机器学习 · 计算机科学 2021-07-28 Guillaume Ausset , Tom Ciffreo , Francois Portier , Stephan Clémençon , Timothée Papin

Diffusion models have risen to prominence in time series forecasting, showcasing their robust capability to model complex data distributions. However, their effectiveness in deterministic predictions is often constrained by instability…

机器学习 · 计算机科学 2024-11-08 Hao Yang , Zhanbo Feng , Feng Zhou , Robert C Qiu , Zenan Ling

One of the most pressing challenges facing the fusion community is adequately mitigating or, even better, avoiding disruptions of tokamak plasmas. However, before this can be done, disruptions must first be predicted with sufficient warning…

等离子体物理 · 物理学 2019-09-04 R. A. Tinguely , K. J. Montes , C. Rea , R. Sweeney , R. S. Granetz