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Embedding & MLP has become a paradigm for modern large-scale recommendation system. However, this paradigm suffers from the cold-start problem which will seriously compromise the ecological health of recommendation systems. This paper…

信息检索 · 计算机科学 2022-05-30 Xu Zhao , Yi Ren , Ying Du , Shenzheng Zhang , Nian Wang

We introduce a multicrossmodal LLM-agent framework motivated by the growing volume and diversity of materials-science data ranging from high-resolution microscopy and dynamic simulation videos to tabular experiment logs and sprawling…

材料科学 · 物理学 2025-05-22 Adib Bazgir , Rama chandra Praneeth Madugula , Yuwen Zhang

In practical chiller systems, applying efficient fault diagnosis techniques can significantly reduce energy consumption and improve energy efficiency of buildings. The success of the existing methods for fault diagnosis of chillers relies…

机器学习 · 计算机科学 2021-02-08 Bingxu Li , Fanyong Cheng , Xin Zhang , Can Cui , Wenjian Cai

The research field of Artificial Life studies how life-like phenomena such as autopoiesis, agency, or self-regulation can self-organize in computer simulations. In cellular automata (CA), a key open-question has been whether it it is…

多智能体系统 · 计算机科学 2024-02-19 Gautier Hamon , Mayalen Etcheverry , Bert Wang-Chak Chan , Clément Moulin-Frier , Pierre-Yves Oudeyer

The pace of soft material formulation (re)development and design is rapidly increasing as both consumers and new legislation demand products that do less harm to the environment while maintaining high standards of performance. To meet this…

软凝聚态物质 · 物理学 2025-06-25 Tyler B. Martin , Duncan R. Sutherland , Austin McDannald , A. Gilad Kusne , Peter A. Beaucage

The quasi-neutral hybrid model with kinetic ions and fluid electrons is a promising approach for bridging the inherent multi-scale nature of many problems in space and laboratory plasmas. Here, a novel, implicit, particle-in-cell based…

等离子体物理 · 物理学 2018-11-14 A. Stanier , L. Chacón , G. Chen

We introduce the first formal large-scale assessment of the utility of traditional chemical functional groups as used in chemical explanations. Our assessment employs a fundamental principle from computational learning theory: a good…

机器学习 · 计算机科学 2025-11-11 Ruben Sharma , Ross D. King

Self-driving laboratories (SDLs) close the loop between experiment design, automated execution, and data-driven decision making, and they provide a demanding testbed for agentic AI under expensive actions, noisy and delayed feedback, strict…

人工智能 · 计算机科学 2026-01-27 Xuanzhou Chen , Audrey Wang , Stanley Yin , Hanyang Jiang , Dong Zhang

We presented a new 3D refinement method for Cryo-EM single particle analysis which can improve the resolution of final electron density map in this paper. We proposed to enforce both sparsity and smoothness to improve the regularity of…

图像与视频处理 · 电气工程与系统科学 2020-03-12 Zhenwei Luo

Effective mixing is essential for biochemical reactions. In droplet-based microfluidics, immediate mixing of substances upon contact in the droplet formation stage can greatly enhance the uniformity of chemical reactions. Furthermore, it…

流体动力学 · 物理学 2024-01-17 Ali Kheirkhah Barzoki , Alireza Mohseni , Mohammad Mehdi Bazyar , Kaivan Mohammadi

Particle picking is a time-consuming step in single-particle analysis and often requires significant interventions from users, which has become a bottleneck for future automated electron cryo-microscopy (cryo-EM). Here we report a deep…

定量方法 · 定量生物学 2016-05-09 Feng Wang , Huichao Gong , Gaochao liu , Meijing Li , Chuangye Yan , Tian Xia , Xueming Li , Jianyang Zeng

Scientific discovery is often slowed by the manual development of computational tools needed to analyze complex experimental data. Building such tools is costly and time-consuming because scientists must iteratively review literature, test…

人工智能 · 计算机科学 2026-05-19 Alistair Turcan , Kexin Huang , Lei Li , Martin Jinye Zhang

We propose a minimal agentic baseline that enables systematic comparison across different AI-based theorem prover architectures. This design implements the core features shared among state-of-the-art systems: iterative proof refinement,…

人工智能 · 计算机科学 2026-05-15 Borja Requena , Austin Letson , Krystian Nowakowski , Izan Beltran-Ferreiro , Leopoldo Sarra

Cryogenic electron microscopy (cryo-EM) has transformed structural biology by allowing to reconstruct 3D biomolecular structures up to near-atomic resolution. However, the 3D reconstruction process remains challenging, as the 3D structures…

计算机视觉与模式识别 · 计算机科学 2023-07-18 Bongjin Koo , Julien Martel , Ariana Peck , Axel Levy , Frédéric Poitevin , Nina Miolane

Resolving the structural variability of proteins is often key to understanding the structure-function relationship of those macromolecular machines. Single particle analysis using Cryogenic electron microscopy (CryoEM), combined with…

定量方法 · 定量生物学 2022-11-22 Muyuan Chen , Bogdan Toader , Roy Lederman

Cryo-electron microscopy (cryo-EM) enables single-particle analysis of biological macromolecules under strict low-dose imaging conditions, but the resulting micrographs often exhibit extremely low signal-to-noise ratios and weak particle…

计算机视觉与模式识别 · 计算机科学 2026-04-21 Xiaoqi Wu , Xueying Zhan , Wen Li , Junhao Wu , Xin Huang , Min Xu

Chemical process optimization maximizes production efficiency and economic performance, but optimization algorithms, including gradient-based solvers, numerical methods, and parameter grid searches, become impractical when operating…

机器学习 · 计算机科学 2025-10-17 Tong Zeng , Srivathsan Badrinarayanan , Janghoon Ock , Cheng-Kai Lai , Amir Barati Farimani

The structure and dynamics of important biological quasi-two-dimensional systems, ranging from cytoskeletal gels to tissues, are controlled by nematic order, flow, defects and activity. Continuum hydrodynamic descriptions combined with…

生物物理 · 物理学 2024-12-03 Waleed Mirza , Alejandro Torres-Sánchez , Guillermo Vilanova , Marino Arroyo

Artificial intelligence (AI) agents are emerging as transformative tools in drug discovery, with the ability to autonomously reason, act, and learn through complicated research workflows. Building on large language models (LLMs) coupled…

In contemporary retail, the variety of products available (e.g. clothing, groceries, cosmetics, frozen goods) make it difficult to predict the demand, prevent stockouts, and find high-potential products. We suggest an agentic AI model that…

人工智能 · 计算机科学 2025-12-01 Toqeer Ali Syed , Salman Jan , Gohar Ali , Ali Akarma , Ahmad Ali , Qurat-ul-Ain Mastoi
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