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Multivariate Time-Series (MTS) clustering is crucial for signal processing and data analysis. Although deep learning approaches, particularly those leveraging Contrastive Learning (CL), are prominent for MTS representation, existing…

机器学习 · 计算机科学 2026-01-13 Zexi Tan , Tao Xie , Haoyi Xiao , Baoyao Yang , Yuzhu Ji , An Zeng , Xiang Zhang , Yiqun Zhang

Analyzing and inspecting bone marrow cell cytomorphology is a critical but highly complex and time-consuming component of hematopathology diagnosis. Recent advancements in artificial intelligence have paved the way for the application of…

计算机视觉与模式识别 · 计算机科学 2022-05-23 Shayan Fazeli , Alireza Samiei , Thomas D. Lee , Majid Sarrafzadeh

In this work, we introduce metrics to evaluate the use of simplified time series in the context of interpretability of a TSC -- a Time Series Classifier. Such simplifications are important because time series data, in contrast to text and…

机器学习 · 计算机科学 2025-11-04 Brigt Håvardstun , Felix Marti-Perez , Cèsar Ferri , Jan Arne Telle

Circadian clocks play a pivotal role in orchestrating numerous physiological and developmental events. Waveform shapes of the oscillations of protein abundances can be informative about the underlying biochemical processes of circadian…

亚细胞过程 · 定量生物学 2018-11-27 Hang-Hyun Jo , Yeon Jeong Kim , Jae Kyoung Kim , Mathias Foo , David E. Somers , Pan-Jun Kim

Information theory is a powerful framework for quantifying complexity, uncertainty, and dynamical structure in time-series data, with widespread applicability across disciplines such as physics, finance, and neuroscience. However, the…

信息论 · 计算机科学 2026-01-26 Annie G. Bryant , Oliver M. Cliff , James M. Shine , Ben D. Fulcher , Joseph T. Lizier

Different cell types aggregate and sort into hierarchical architectures during the formation of animal tissues. The resulting spatial organization depends (in part) on the strength of adhesion of one cell type to itself relative to other…

定量方法 · 定量生物学 2023-08-02 Dhananjay Bhaskar , William Y. Zhang , Alexandria Volkening , Björn Sandstede , Ian Y. Wong

The automatic classification of medical time series signals, such as electroencephalogram (EEG) and electrocardiogram (ECG), plays a pivotal role in clinical decision support and early detection of diseases. Although Transformer based…

机器学习 · 计算机科学 2025-09-22 Ming Hu , Jianfu Yin , Mingyu Dou , Yuqi Wang , Ruochen Dang , Siyi Liang , Feiyu Zhu , Cong Hu , Yao Wang , Bingliang Hu , Quan Wang

Within the diverse interdisciplinary life sciences domains, semantic, workflow, and methodological ambiguities can prevent the appreciation of explanations of phenomena, handicap the use of computational models, and hamper communication…

Several experimental studies claim to be able to predict the outcome of simple decisions from brain signals measured before subjects are aware of their decision. Often, these studies use multivariate pattern recognition methods with the…

神经元与认知 · 定量生物学 2016-06-21 Marco Rusconi , Angelo Valleriani

We develop a framework to track the structure of temporal networks with a signal processing approach. The method is based on the duality between networks and signals using a multidimensional scaling technique. This enables a study of the…

社会与信息网络 · 计算机科学 2015-05-13 Ronan Hamon , Pierre Borgnat , Patrick Flandrin , Céline Robardet

Physiological signals such as electrocardiograms (ECG) and electroencephalograms (EEG) provide complementary insights into human health and cognition, yet multi-modal integration is challenging due to limited multi-modal labeled data, and…

Audiovisual data is everywhere in this digital age, which raises higher requirements for the deep learning models developed on them. To well handle the information of the multi-modal data is the key to a better audiovisual modal. We observe…

声音 · 计算机科学 2023-09-27 Meng Liu , Ke Liang , Dayu Hu , Hao Yu , Yue Liu , Lingyuan Meng , Wenxuan Tu , Sihang Zhou , Xinwang Liu

Within the context of topological data analysis, the problems of identifying topological significance and matching signals across datasets are important and useful inferential tasks in many applications. The limitation of existing solutions…

代数拓扑 · 数学 2024-06-26 Inés García-Redondo , Anthea Monod , Anna Song

Recent advances in deep learning architectures for sequence modeling have not fully transferred to tasks handling time-series from electronic health records. In particular, in problems related to the Intensive Care Unit (ICU), the…

机器学习 · 计算机科学 2024-02-07 Rita Kuznetsova , Alizée Pace , Manuel Burger , Hugo Yèche , Gunnar Rätsch

Tracking cells in time-lapse videos is an essential technique for monitoring cell population dynamics at a single-cell level. Current methods for cell tracking are developed on videos with mostly single, constant signals and do not detect…

计算机视觉与模式识别 · 计算机科学 2025-12-17 Florian Bürger , Martim Dias Gomes , Nica Gutu , Adrián E. Granada , Noémie Moreau , Katarzyna Bozek

Biological multimodal large language models (MLLMs) have emerged as powerful foundation models for scientific discovery. However, existing models are specialized to a single modality, limiting their ability to solve inherently cross-modal…

机器学习 · 计算机科学 2026-03-17 Wonbin Lee , Dongki Kim , Sung Ju Hwang

Complex systems are commonly modeled using nonlinear dynamical systems. These models are often high-dimensional and chaotic. An important goal in studying physical systems through the lens of mathematical models is to determine when the…

计算几何 · 计算机科学 2014-03-25 Jesse Berwald , Marian Gidea , Mikael Vejdemo-Johansson

Determination of the nature of the dynamical state of a system as a function of its parameters is an important problem in the study of dynamical systems. This problem becomes harder in experimental systems where the obtained data is…

混沌动力学 · 物理学 2024-08-29 Rishab Antosh , Sanjit Das , N. Nirmal Thyagu

Multi-modal high throughput biological data presents a great scientific opportunity and a significant computational challenge. In multi-modal measurements, every sample is observed simultaneously by two or more sets of sensors. In such…

机器学习 · 计算机科学 2023-03-17 Junchen Yang , Ofir Lindenbaum , Yuval Kluger , Ariel Jaffe

Deep, high-resolution imaging is essential for unraveling biological complexity and advancing medical diagnostics, yet scattering fundamentally limits optical methods. Among the most promising approaches, photoacoustic imaging achieves…