相关论文: Fine-tuning Pocket-Aware Diffusion Models via Deno…

Due to the high complexity and technical requirements of industrial production processes, surface defects will inevitably appear, which seriously affects the quality of products. Although existing lightweight detection networks are highly…

Masked diffusion language models generate text through iterative masked-token filling, but terminal-only rewards on final completions provide coarse credit assignment for the intermediate filling decisions that shape the generation process.…

Without using explicit reward, direct preference optimization (DPO) employs paired human preference data to fine-tune generative models, a method that has garnered considerable attention in large language models (LLMs). However, exploration…

We aim to solve the problem of generating coarse-to-fine skills learning from demonstrations (LfD). To scale precision, traditional LfD approaches often rely on extensive fine-grained demonstrations with external interpolations or dynamics…

Masked Diffusion Models (MDMs) offer flexible, non-autoregressive generation, but this freedom introduces a challenge: final output quality is highly sensitive to the decoding order. We are the first to formalize this issue, attributing the…

Diffusion Policies have become widely used in Imitation Learning, offering several appealing properties, such as generating multimodal and discontinuous behavior. As models are becoming larger to capture more complex capabilities, their…

Recent studies, including DeepSeek-R1 and Kimi-k1.5, have demonstrated that reinforcement learning with rule-based, binary-valued reward functions can significantly enhance the reasoning capabilities of large language models. These models…

We propose Diffusion-Sharpening, a fine-tuning approach that enhances downstream alignment by optimizing sampling trajectories. Existing RL-based fine-tuning methods focus on single training timesteps and neglect trajectory-level alignment,…

Computational models that accurately predict the binding affinity of an input protein-chemical pair can accelerate drug discovery studies. These models are trained on available protein-chemical interaction datasets, which may contain…

Controllable diffusion generation often relies on various heuristics that are seemingly disconnected without a unified understanding. We bridge this gap with Diffusion Controller (DiffCon), a unified control-theoretic view that casts…

Drug discovery is a highly complicated process, and it is unfeasible to fully commit it to the recently developed molecular generation methods. Deep learning-based lead optimization takes expert knowledge as a starting point, learning from…

Discrete diffusion models have demonstrated great promise in modeling various sequence data, ranging from human language to biological sequences. Inspired by the success of RL in language models, there is growing interest in further…

Recent studies have demonstrated the effectiveness of directly aligning diffusion models with human preferences using differentiable reward. However, they exhibit two primary challenges: (1) they rely on multistep denoising with gradient…

Structure-based drug design (SBDD) aims to discover drug candidates by finding molecules (ligands) that bind tightly to a disease-related protein (targets), which is the primary approach to computer-aided drug discovery. Recently, applying…

Parameter-Efficient FineTuning (PEFT) methods have recently gained significant popularity thanks to the widespread availability of large-scale pretrained models. These methods allow for quick adaptation to downstream tasks with minimal…

Recent advances align diffusion models with human preferences to increase aesthetic appeal and mitigate artifacts and biases. Such methods aim to maximize a conditional output distribution aligned with higher rewards whilst not drifting far…

We present PANDORA, a novel diffusion-based policy learning framework designed specifically for dexterous robotic piano performance. Our approach employs a conditional U-Net architecture enhanced with FiLM-based global conditioning, which…

Low-dose computed tomography (LDCT) lower potential risks linked to radiation exposure while relying on advanced denoising algorithms to maintain diagnostic quality in reconstructed images. The reigning paradigm in LDCT denoising is based…

Diffusion policies have recently emerged as a powerful class of visuomotor controllers for robot manipulation, offering stable training and expressive multi-modal action modeling. However, existing approaches typically treat action…

Diffusion models have been recently employed to improve certified robustness through the process of denoising. However, the theoretical understanding of why diffusion models are able to improve the certified robustness is still lacking,…