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To be fully useful for public health practice, models for epidemic response must be able to do more than predict -- it is also important to incorporate the mechanisms underlying transmission dynamics to enable policymakers and practitioners…

定量方法 · 定量生物学 2025-05-26 Jiale Tan , Marisa C. Eisenberg

Gene-gene and gene-environment interactions are widely believed to play significant roles in explaining the variability of complex traits. While substantial research exists in this area, a comprehensive statistical framework that addresses…

统计方法学 · 统计学 2026-02-18 Durba Bhattacharya , Sourabh Bhattacharya

Recent advances in the field of meta-learning have tackled domains consisting of large numbers of small ("few-shot") supervised learning tasks. Meta-learning algorithms must be able to rapidly adapt to any individual few-shot task, fitting…

机器学习 · 计算机科学 2021-10-22 Vivek Myers , Nikhil Sardana

By interpreting the forward dynamics of the latent representation of neural networks as an ordinary differential equation, Neural Ordinary Differential Equation (Neural ODE) emerged as an effective framework for modeling a system dynamics…

机器学习 · 计算机科学 2020-10-19 Daehoon Gwak , Gyuhyeon Sim , Michael Poli , Stefano Massaroli , Jaegul Choo , Edward Choi

We consider nonparametric measurement error density deconvolution subject to heteroscedastic measurement errors as well as symmetry about zero and shape constraints, in particular unimodality. The problem is motivated by applications where…

统计方法学 · 统计学 2020-02-19 Ya Su , Anirban Bhattacharya , Yan Zhang , Nilanjan Chatterjee , Raymond J. Carroll

Leveraging multivariate spatial dependence to improve the precision of estimates using American Community Survey data and other sample survey data has been a topic of recent interest among data-users and federal statistical agencies. One…

应用统计 · 统计学 2024-01-19 Ryan Janicki , Andrew M. Raim , Scott H. Holan , Jerry Maples

In many scientific and engineering domains, physical experiments are often costly, non-replicable, or time-consuming. The Kennedy and O'Hagan (KOH) model framework has become a widely used approach for combining simulator runs with limited…

统计计算 · 统计学 2026-03-18 Hao Zhu , Markus Hainy

Hybrid models composing mechanistic ODE-based dynamics with flexible and expressive neural network components have grown rapidly in popularity, especially in scientific domains where such ODE-based modeling offers important interpretability…

机器学习 · 计算机科学 2026-02-02 Bob Junyi Zou , Matthew E. Levine , Dessi P. Zaharieva , Ramesh Johari , Emily B. Fox

Parameter identification problems in partial differential equations (PDEs) consist in determining one or more functional coefficient in a PDE. In this article, the Bayesian nonparametric approach to such problems is considered. Focusing on…

统计理论 · 数学 2025-04-24 Matteo Giordano

Stochastic differential equations (SDEs) are established tools to model physical phenomena whose dynamics are affected by random noise. By estimating parameters of an SDE intrinsic randomness of a system around its drift can be identified…

统计计算 · 统计学 2012-05-03 Umberto Picchini , Susanne Ditlevsen

Interactions among multiple time series of positive random variables are crucial in diverse financial applications, from spillover effects to volatility interdependence. A popular model in this setting is the vector Multiplicative Error…

统计计算 · 统计学 2021-07-12 Nicola Donelli , Stefano Peluso , Antonietta Mira

In image reconstruction, an accurate quantification of uncertainty is of great importance for informed decision making. Here, the Bayesian approach to inverse problems can be used: the image is represented through a random function that…

数值分析 · 数学 2025-04-24 Jonas Latz , Aretha L. Teckentrup , Simon Urbainczyk

A key challenge with controlling complex dynamical systems is to accurately model them. However, this requirement is very hard to satisfy in practice. Data-driven approaches such as Gaussian processes (GPs) have proved quite effective by…

机器人学 · 计算机科学 2022-03-08 Mouhyemen Khan , Akash Patel , Abhijit Chatterjee

Graphical model has been widely used to investigate the complex dependence structure of high-dimensional data, and it is common to assume that observed data follow a homogeneous graphical model. However, observations usually come from…

统计方法学 · 统计学 2016-01-01 Kevin Lee , Lingzhou Xue

Many real-world systems are modelled using complex ordinary differential equations (ODEs). However, the dimensionality of these systems can make them challenging to analyze. Dimensionality reduction techniques like Proper Orthogonal…

计算工程、金融与科学 · 计算机科学 2025-02-26 Abhishek Ajayakumar , Soumyendu Raha

Deep generative models such as flow matching and diffusion models have shown great potential in learning complex distributions and dynamical systems, but often act as black-boxes, neglecting underlying physics. In contrast, physics-based…

机器学习 · 计算机科学 2026-04-28 Gurjeet Sangra Singh , Frantzeska Lavda , Giangiacomo Mercatali , Alexandros Kalousis

This paper demonstrates the advantages of sharing information about unknown features of covariates across multiple model components in various nonparametric regression problems including multivariate, heteroscedastic, and semi-continuous…

统计方法学 · 统计学 2019-06-11 Antonio R. Linero , Debajyoti Sinha , Stuart R. Lipsitz

Mixture-of-Experts (MoE) is a flexible framework that combines multiple specialized submodels (``experts''), by assigning covariate-dependent weights (``gating functions'') to each expert, and have been commonly used for analyzing…

统计方法学 · 统计学 2026-01-06 Qicheng Zhao , Celia M. T. Greenwood , Qihuang Zhang

Identification of parameters in ordinary differential equations (ODEs) is an important and challenging task when modeling dynamic systems in biomedical research and other scientific areas, especially with the presence of time-varying…

统计方法学 · 统计学 2022-03-02 Yan Sun , Shihao Yang

This paper introduces a novel hybrid model combining Partial Differential Equations (PDEs) and Ordinary Differential Equations (ODEs) to simulate infectious disease dynamics across geographic regions. By leveraging the spatial detail of…

动力系统 · 数学 2025-11-18 Kristina Kehrer , Martin Weiser , Tim Conrad