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Blood vessel networks in the brain play a crucial role in stroke research, where understanding their topology is essential for analyzing blood flow dynamics. However, extracting detailed topological vessel network information from…

计算机视觉与模式识别 · 计算机科学 2025-04-17 Joël Mathys , Andreas Plesner , Jorel Elmiger , Roger Wattenhofer

Single-cell RNA sequencing (scRNA-seq) has the potential to provide powerful, high-resolution signatures to inform disease prognosis and precision medicine. This paper takes an important first step towards this goal by developing an…

定量方法 · 定量生物学 2021-10-15 Bryan He , Matthew Thomson , Meena Subramaniam , Richard Perez , Chun Jimmie Ye , James Zou

Progress in anatomical 3D shape classification is limited by the complexity of mesh data and the lack of standardized benchmarks, highlighting the need for robust learning methods and reproducible evaluation. We introduce two key steps…

计算机视觉与模式识别 · 计算机科学 2025-11-04 Tomáš Krsička , Tibor Kubík

Clustering analysis is fundamental in single-cell RNA sequencing (scRNA-seq) data analysis for elucidating cellular heterogeneity and diversity. Recent graph-based scRNA-seq clustering methods, particularly graph neural networks (GNNs),…

机器学习 · 计算机科学 2025-07-15 Ping Xu , Pengfei Wang , Zhiyuan Ning , Meng Xiao , Min Wu , Yuanchun Zhou

Computer vision and machine learning tools offer an exciting new way for automatically analyzing and categorizing information from complex computer simulations. Here we design an ensemble machine learning framework that can independently…

计算机视觉与模式识别 · 计算机科学 2021-09-06 Maarja Bussov , Joonas Nättilä

Single-cell RNA sequencing (scRNA-seq) is powerful technology that allows researchers to understand gene expression patterns at the single-cell level. However, analysing scRNA-seq data is challenging due to issues and biases in data…

基因组学 · 定量生物学 2023-12-14 Jinlu Liu , Sara Wade , Natalia Bochkina

Geometrical structures and the internal local region relationship, such as symmetry, regular array, junction, etc., are essential for understanding a 3D shape. This paper proposes a point cloud feature extraction network named PointSCNet,…

计算机视觉与模式识别 · 计算机科学 2024-06-18 Xingye Chen , Yiqi Wu , Wenjie Xu , Jin Li , Huaiyi Dong , Yilin Chen

Accurate multi-class tubular modeling is critical for precise lesion localization and optimal treatment planning. Deep learning methods enable automated shape modeling by prioritizing volumetric overlap accuracy. However, the inherent…

图像与视频处理 · 电气工程与系统科学 2025-06-17 Minghui Zhang , Yaoyu Liu , Xin You , Hanxiao Zhang , Yun Gu

Automated phenotyping of plants for breeding and plant studies promises to provide quantitative metrics on plant traits at a previously unattainable observation frequency. Developers of tools for performing high-throughput phenotyping are,…

计算机视觉与模式识别 · 计算机科学 2024-03-04 Katherine Margaret Frances James , Karoline Heiwolt , Daniel James Sargent , Grzegorz Cielniak

A hierarchical ensemble pipeline is introduced to address anomaly detection in multivariate telemetry data provided by European Space Agency (ESA). The method integrates shapelet-based and statistical feature extraction, per-channel…

机器学习 · 计算机科学 2026-05-12 Lorenzo Riccardo Allegrini , Geremia Pompei

With the rapid adoption of machine learning techniques for large-scale applications in science and engineering comes the convergence of two grand challenges in visualization. First, the utilization of black box models (e.g., deep neural…

Since the PointNet was proposed, deep learning on point cloud has been the concentration of intense 3D research. However, existing point-based methods usually are not adequate to extract the local features and the spatial pattern of a point…

计算机视觉与模式识别 · 计算机科学 2020-04-01 Weikun Wu , Yan Zhang , David Wang , Yunqi Lei

Topology Bench is a comprehensive topology dataset designed to accelerate benchmarking studies in optical networks. The dataset, focusing on core optical networks, comprises publicly accessible and ready-to-use topologies, including (a) 105…

网络与互联网体系结构 · 计算机科学 2024-11-08 Robin Matzner , Akanksha Ahuja , Rasoul Sadeghi , Michael Doherty , Alejandra Beghelli , Seb J. Savory , Polina Bayvel

We present a novel method for automated identification of putative cell types from single-cell RNA-seq (scRNA-seq) data. By iteratively applying a machine learning approach to an initial clustering of gene expression profiles of a given set…

定量方法 · 定量生物学 2020-04-22 Zhichao Miao , Pablo Moreno , Ni Huang , Irene Papatheodorou , Alvis Brazma , Sarah A Teichmann

We introduce deep neural networks for the analysis of anatomical shapes that learn a low-dimensional shape representation from the given task, instead of relying on hand-engineered representations. Our framework is modular and consists of…

计算机视觉与模式识别 · 计算机科学 2020-10-05 Benjamin Gutierrez Becker , Ignacio Sarasua , Christian Wachinger

Single-cell RNA sequencing (scRNA-seq) is widely used to reveal heterogeneity in cells, which has given us insights into cell-cell communication, cell differentiation, and differential gene expression. However, analyzing scRNA-seq data is a…

机器学习 · 计算机科学 2023-06-27 Yuta Hozumi , Gu-Wei Wei

The development of single-cell and spatial transcriptomics has revolutionized our capacity to investigate cellular properties, functions, and interactions in both cellular and spatial contexts. However, the analysis of single-cell and…

基因组学 · 定量生物学 2024-12-09 Shuang Ge , Shuqing Sun , Huan Xu , Qiang Cheng , Zhixiang Ren

Training deep learning models on single-cell datasets with hundreds of millions of cells requires loading data from disk, as these datasets exceed available memory. While random sampling provides the data diversity needed for effective…

机器学习 · 计算机科学 2026-01-30 Davide D'Ascenzo , Sebastiano Cultrera di Montesano

Despite the breakthroughs in biomarker discovery facilitated by differential gene analysis, challenges remain, particularly at the single-cell level. Traditional methodologies heavily rely on user-supplied cell annotations, focusing on…

基因组学 · 定量生物学 2023-12-29 Chenyu Liu , Yong Jin Kweon , Jun Ding

In high-dimensional and high-stakes contexts, ensuring both rigorous statistical guarantees and interpretability in feature extraction from complex tabular data remains a formidable challenge. Traditional methods such as Principal Component…

机器学习 · 计算机科学 2025-03-25 Xiaochen Zhang , Haoyi Xiong