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We study how to impose domain-consistent structure on large language models (LLMs) used for scientific reasoning and early-stage drug discovery. We present MedRule-KG, a compact knowledge-graph scaffold paired with a lightweight verifier…

人工智能 · 计算机科学 2025-12-15 Crystal Su

Most phenomena related to biomedical tasks are inherently complex, and in many cases, are expressed as signals on biomedical Knowledge Graphs (KGs). In this work, we introduce the use of a new representation framework, the Prime Adjacency…

定量方法 · 定量生物学 2023-05-19 Konstantinos Bougiatiotis , Georgios Paliouras

Foundation models (FMs) are able to leverage large volumes of unlabeled data to demonstrate superior performance across a wide range of tasks. However, FMs developed for biomedical domains have largely remained unimodal, i.e., independently…

In the last few years, the solution to Knowledge Graph (KG) completion via learning embeddings of entities and relations has attracted a surge of interest. Temporal KGs(TKGs) extend traditional Knowledge Graphs (KGs) by associating static…

人工智能 · 计算机科学 2023-02-14 Zhongwu Chen , Chengjin Xu , Fenglong Su , Zhen Huang , You Dou

Knowledge Graph Embeddings (KGEs) support a wide range of downstream tasks over Knowledge Graphs (KGs). In practice, KGs evolve as new entities and facts are added, motivating Continual Knowledge Graph Embedding (CKGE) methods that update…

机器学习 · 计算机科学 2026-04-22 Gerard Pons , Carlos Escolano , Besim Bilalli , Anna Queralt

Schema matching is a critical task in data integration, particularly in the medical domain where disparate Electronic Health Record (EHR) systems must be aligned to standard models like OMOP CDM. While Large Language Models (LLMs) have…

人工智能 · 计算机科学 2025-12-02 Mingyu Jeon , Jaeyoung Suh , Suwan Cho

Link prediction is a pivotal task in graph mining with wide-ranging applications in social networks, recommendation systems, and knowledge graph completion. However, many leading Graph Neural Network (GNN) models often neglect the valuable…

社会与信息网络 · 计算机科学 2025-11-11 Ankit Mazumder , Srikanta Bedathur

As the field of Large Language Models (LLMs) evolves at an accelerated pace, the critical need to assess and monitor their performance emerges. We introduce a benchmarking framework focused on knowledge graph engineering (KGE) accompanied…

The availability of vast amounts of visual data with heterogeneous features is a key factor for developing, testing, and benchmarking of new computer vision (CV) algorithms and architectures. Most visual datasets are created and curated for…

计算机视觉与模式识别 · 计算机科学 2024-03-29 Jicheng Yuan , Anh Le-Tuan , Manh Nguyen-Duc , Trung-Kien Tran , Manfred Hauswirth , Danh Le-Phuoc

In recent years, there has been substantial progress in using pretrained Language Models (LMs) on a range of tasks aimed at improving the understanding of biomedical texts. Nonetheless, existing biomedical LLMs show limited comprehension of…

计算与语言 · 计算机科学 2025-09-10 Andrey Sakhovskiy , Elena Tutubalina

Clinical practice guidelines are long, multimodal documents whose branching recommendations are difficult to convert into executable clinical decision support (CDS), and one-shot parsing often breaks cross-page continuity. Recent LLM/VLM…

计算机视觉与模式识别 · 计算机科学 2026-04-06 Onur Selim Kilic , Yeti Z. Gurbuz , Cem O. Yaldiz , Afra Nawar , Etrit Haxholli , Ogul Can , Eli Waxman

Traditional knowledge graph (KG) embedding methods aim to represent entities and relations in a low-dimensional space, primarily focusing on static graphs. However, real-world KGs are dynamically evolving with the constant addition of…

人工智能 · 计算机科学 2025-08-18 Yifei Li , Lingling Zhang , Hang Yan , Tianzhe Zhao , Zihan Ma , Muye Huang , Jun Liu

Knowledge graphs and ontologies represent entities and their relationships in a structured way, having gained significance in the development of modern AI applications. Integrating these semantic resources with machine learning models often…

机器学习 · 计算机科学 2025-09-10 Hamid Ahmad , Heiko Paulheim , Rita T. Sousa

Large language models (LLMs) have demonstrated impressive capabilities in language tasks, but they require high computing power and rely on static knowledge. To overcome these limitations, Retrieval-Augmented Generation (RAG) incorporates…

分布式、并行与集群计算 · 计算机科学 2025-02-17 Jiaxing Li , Chi Xu , Lianchen Jia , Feng Wang , Cong Zhang , Jiangchuan Liu

Traditional knowledge graph embedding (KGE) methods typically require preserving the entire knowledge graph (KG) with significant training costs when new knowledge emerges. To address this issue, the continual knowledge graph embedding…

人工智能 · 计算机科学 2024-05-08 Jiajun Liu , Wenjun Ke , Peng Wang , Ziyu Shang , Jinhua Gao , Guozheng Li , Ke Ji , Yanhe Liu

The automatic construction of knowledge graphs (KGs) is an important research area in medicine, with far-reaching applications spanning drug discovery and clinical trial design. These applications hinge on the accurate identification of…

计算与语言 · 计算机科学 2025-01-30 Vahan Arsenyan , Spartak Bughdaryan , Fadi Shaya , Kent Small , Davit Shahnazaryan

Biomedical datasets are often modeled as knowledge graphs (KGs) because they capture the multi-relational, heterogeneous, and dynamic natures of biomedical systems. KG completion (KGC), can, therefore, help researchers make predictions to…

Knowledge Graph has been proven effective in modeling structured information and conceptual knowledge, especially in the medical domain. However, the lack of high-quality annotated corpora remains a crucial problem for advancing the…

计算与语言 · 计算机科学 2021-09-22 Dejie Chang , Mosha Chen , Chaozhen Liu , Liping Liu , Dongdong Li , Wei Li , Fei Kong , Bangchang Liu , Xiaobin Luo , Ji Qi , Qiao Jin , Bin Xu

Large Language Models (LLMs) have significantly advanced medical question-answering by leveraging extensive clinical data and medical literature. However, the rapid evolution of medical knowledge and the labor-intensive process of manually…

计算与语言 · 计算机科学 2025-07-01 Mohammad Reza Rezaei , Reza Saadati Fard , Jayson L. Parker , Rahul G. Krishnan , Milad Lankarany

Recent studies in medical question answering (Medical QA) have actively explored the integration of large language models (LLMs) with biomedical knowledge graphs (KGs) to improve factual accuracy. However, most existing approaches still…

计算与语言 · 计算机科学 2026-01-15 Chaerin Lee , Sohee Park , Hyunsik Na , Daseon Choi