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Self-driving laboratories (SDLs) close the loop between experiment design, automated execution, and data-driven decision making, and they provide a demanding testbed for agentic AI under expensive actions, noisy and delayed feedback, strict…

人工智能 · 计算机科学 2026-01-27 Xuanzhou Chen , Audrey Wang , Stanley Yin , Hanyang Jiang , Dong Zhang

Artificial intelligence (AI) has transformed digital pathology by enabling biomarker prediction from high-resolution whole-slide images (WSIs). However, current methods are computationally inefficient, processing thousands of redundant…

Guiding large language models with a selected set of human-authored demonstrations is a common practice for improving LLM applications. However, human effort can be costly, especially in specialized domains (e.g., clinical diagnosis), and…

人工智能 · 计算机科学 2024-08-23 Kai Tzu-iunn Ong , Taeyoon Kwon , Jinyoung Yeo

Dermatological care via telemedicine often lacks the rich context of in-person visits. Clinicians must make diagnoses based on a handful of images and brief descriptions, without the benefit of physical exams, second opinions, or reference…

人工智能 · 计算机科学 2025-08-27 Karishma Thakrar , Shreyas Basavatia , Akshay Daftardar

Deep learning models in medical imaging typically operate as parametric memory, diagnosing patients by recalling fixed knowledge learned during training. This contrasts sharply with clinical practice, where physicians employ analogical…

计算机视觉与模式识别 · 计算机科学 2026-05-12 Lujia Zhong , Yihao Xia , Shuo Huang , Jianwei Zhang , Yonggang Shi

Pathology deals with the practice of discovering the reasons for disease by analyzing the body samples. The most used way in this field, is to use histology which is basically studying and viewing microscopic structures of cell and tissues.…

图像与视频处理 · 电气工程与系统科学 2021-11-08 Virender Ranga , Shivam Gupta , Priyansh Agrawal , Jyoti Meena

Vision-language models (VLMs) have the potential to become co-pilots for pathologists. However, most VLMs either focus on small regions of interest within whole-slide images, provide only static slide-level outputs, or rely on data that is…

计算机视觉与模式识别 · 计算机科学 2026-04-16 Sander Moonemans , Sebastiaan Ram , Frédérique Meeuwsen , Carlijn Lems , Jeroen van der Laak , Geert Litjens , Francesco Ciompi

Pathology detection and delineation enables the automatic interpretation of medical scans such as chest X-rays while providing a high level of explainability to support radiologists in making informed decisions. However, annotating…

计算机视觉与模式识别 · 计算机科学 2023-09-07 Philip Müller , Felix Meissen , Johannes Brandt , Georgios Kaissis , Daniel Rueckert

Pathological diagnosis remains the definitive standard for identifying tumors. The rise of multimodal large models has simplified the process of integrating image analysis with textual descriptions. Despite this advancement, the substantial…

计算机视觉与模式识别 · 计算机科学 2024-08-14 Xiaomin Wu , Rui Xu , Pengchen Wei , Wenkang Qin , Peixiang Huang , Ziheng Li , Lin Luo

Pathological image analysis is a crucial field in computer-aided diagnosis, where deep learning is widely applied. Transfer learning using pre-trained models initialized on natural images has effectively improved the downstream pathological…

图像与视频处理 · 电气工程与系统科学 2023-10-30 Nan Ying , Yanli Lei , Tianyi Zhang , Shangqing Lyu , Chunhui Li , Sicheng Chen , Zeyu Liu , Yu Zhao , Guanglei Zhang

Whole-slide image (WSI) preprocessing, comprising tissue detection followed by patch extraction, is foundational to AI-driven computational pathology but remains a major bottleneck for scaling to large and heterogeneous cohorts. We present…

From self-supervised, vision-only models to contrastive visual-language frameworks, computational pathology has rapidly evolved in recent years. Generative AI "co-pilots" now demonstrate the ability to mine subtle, sub-visual tissue cues…

计算机视觉与模式识别 · 计算机科学 2025-02-13 Mohsin Bilal , Aadam , Manahil Raza , Youssef Altherwy , Anas Alsuhaibani , Abdulrahman Abduljabbar , Fahdah Almarshad , Paul Golding , Nasir Rajpoot

Grading precancerous lesions on whole slide images is a challenging task: the continuous space of morphological phenotypes makes clear-cut decisions between different grades often difficult, leading to low inter- and intra-rater agreements.…

图像与视频处理 · 电气工程与系统科学 2023-03-09 Mélanie Lubrano , Yaëlle Bellahsen-Harrar , Rutger Fick , Cécile Badoual , Thomas Walter

Foundation models are reshaping computational pathology by enabling transfer learning, where models pre-trained on vast datasets can be adapted for downstream diagnostic, prognostic, and therapeutic response tasks. Despite these advances,…

The deployment of AI models in clinical practice faces a critical challenge: models achieving expert-level performance on benchmarks can fail catastrophically when confronted with real-world variations in medical imaging. Minor shifts in…

人工智能 · 计算机科学 2025-07-09 Lukas Kuhn , Florian Buettner

Computer-aided diagnosis (CADx) algorithms in medicine provide patient-specific decision support for physicians. These algorithms are usually applied after full acquisition of high-dimensional multimodal examination data, and often assume…

机器学习 · 计算机科学 2020-10-15 Gerome Vivar , Kamilia Mullakaeva , Andreas Zwergal , Nassir Navab , Seyed-Ahmad Ahmadi

There exist numerous diagnostic tasks in pathology. Conventional computational pathology formulates and tackles them as independent and individual image classification problems, thereby resulting in computational inefficiency and high…

图像与视频处理 · 电气工程与系统科学 2024-07-15 Anh Tien Nguyen , Keunho Byeon , Kyungeun Kim , Boram Song , Seoung Wan Chae , Jin Tae Kwak

Multiple Instance Learning (MIL) is the leading approach for whole slide image (WSI) classification, enabling efficient analysis of gigapixel pathology slides. Recent work has introduced vision-language models (VLMs) into MIL pipelines to…

计算机视觉与模式识别 · 计算机科学 2025-11-19 Ngoc Bui Lam Quang , Nam Le Nguyen Binh , Thanh-Huy Nguyen , Le Thien Phuc Nguyen , Quan Nguyen , Ulas Bagci

Adapting production-level computer vision tools to bespoke scientific datasets is a critical "last mile" bottleneck. Current solutions are impractical: fine-tuning requires large annotated datasets scientists often lack, while manual code…

Learning from experience is critical for building capable large language model (LLM) agents, yet prevailing self-evolving paradigms remain inefficient: agents learn in isolation, repeatedly rediscover similar behaviors from limited…

计算与语言 · 计算机科学 2026-04-21 Chenxi Wang , Zhuoyun Yu , Xin Xie , Wuguannan Yao , Runnan Fang , Shuofei Qiao , Kexin Cao , Guozhou Zheng , Xiang Qi , Peng Zhang , Shumin Deng