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Artificial intelligence (AI) solutions that automatically extract information from digital histology images have shown great promise for improving pathological diagnosis. Prior to routine use, it is important to evaluate their predictive…

Agentic AI systems have gained significant attention for their ability to autonomously perform complex tasks. However, their reliance on well-prepared tools limits their applicability in the medical domain, which requires to train…

计算机视觉与模式识别 · 计算机科学 2025-02-28 Jinghao Feng , Qiaoyu Zheng , Chaoyi Wu , Ziheng Zhao , Ya Zhang , Yanfeng Wang , Weidi Xie

Explaining deep learning models is essential for clinical integration of medical image analysis systems. A good explanation highlights if a model depends on spurious features that undermines generalization and harms a subset of patients or,…

图像与视频处理 · 电气工程与系统科学 2025-08-18 Yoni Schirris , Eric Marcus , Jonas Teuwen , Hugo Horlings , Efstratios Gavves

Whole slide images (WSIs) are vital in digital pathology, enabling gigapixel tissue analysis across various pathological tasks. While recent advancements in multi-modal large language models (MLLMs) allow multi-task WSI analysis through…

计算机视觉与模式识别 · 计算机科学 2025-07-22 Xinheng Lyu , Yuci Liang , Wenting Chen , Meidan Ding , Jiaqi Yang , Guolin Huang , Daokun Zhang , Xiangjian He , Linlin Shen

Advances in digitizing tissue slides and the fast-paced progress in artificial intelligence, including deep learning, have boosted the field of computational pathology. This field holds tremendous potential to automate clinical diagnosis,…

图像与视频处理 · 电气工程与系统科学 2024-01-17 Andrew H. Song , Guillaume Jaume , Drew F. K. Williamson , Ming Y. Lu , Anurag Vaidya , Tiffany R. Miller , Faisal Mahmood

Recent breakthroughs in self-supervised learning have enabled the use of large unlabeled datasets to train visual foundation models that can generalize to a variety of downstream tasks. While this training paradigm is well suited for the…

Current multi-instance learning algorithms for pathology image analysis often require a substantial number of Whole Slide Images for effective training but exhibit suboptimal performance in scenarios with limited learning data. In clinical…

计算机视觉与模式识别 · 计算机科学 2024-07-16 Linhao Qu , Dingkang Yang , Dan Huang , Qinhao Guo , Rongkui Luo , Shaoting Zhang , Xiaosong Wang

Advances in foundation modeling have reshaped computational pathology. However, the increasing number of available models and lack of standardized benchmarks make it increasingly complex to assess their strengths, limitations, and potential…

计算机视觉与模式识别 · 计算机科学 2025-02-11 Andrew Zhang , Guillaume Jaume , Anurag Vaidya , Tong Ding , Faisal Mahmood

Deep learning methods have emerged as powerful tools for analyzing histopathological images, but current methods are often specialized for specific domains and software environments, and few open-source options exist for deploying models in…

Building and deploying machine learning solutions in healthcare remains expensive and labor-intensive due to fragmented preprocessing workflows, model compatibility issues, and stringent data privacy constraints. In this work, we introduce…

人工智能 · 计算机科学 2025-07-25 Soorya Ram Shimgekar , Shayan Vassef , Abhay Goyal , Navin Kumar , Koustuv Saha

While Large Language Models (LLMs) have empowered AI research agents to perform isolated scientific tasks, automating complex, real-world workflows, such as LLM training, remains a significant challenge. In this paper, we introduce TREX, a…

人工智能 · 计算机科学 2026-04-23 Zerun Ma , Guoqiang Wang , Xinchen Xie , Yicheng Chen , He Du , Bowen Li , Yanan Sun , Wenran Liu , Kai Chen , Yining Li

The emergence of tool-calling-based agent systems introduces a more evidence-driven paradigm for pathology image analysis in contrast to the coarse-grained text-image diagnostic approaches. With the recent large-scale experimental adoption…

人工智能 · 计算机科学 2026-02-24 Haoyang Su , Shaoting Zhang , Xiaosong Wang

Developing AI models that are useful in clinical practice, requires efficient collaboration between clinicians and AI developers. This poses a practical challenge: clinicians must repeatedly communicate and refine their requirements with AI…

计算机视觉与模式识别 · 计算机科学 2026-05-28 Zihao Zhao , Frederik Hauke , Juliana De Castilhos , Mathis Bode , Jakob Nikolas Kather , Sven Nebelung , Daniel Truhn

Training AI models has always been challenging, especially when there is a need for custom models to provide personalized services. Algorithm engineers often face a lengthy process to iteratively develop models tailored to specific business…

人工智能 · 计算机科学 2023-11-27 Haoyuan Li , Hao Jiang , Tianke Zhang , Zhelun Yu , Aoxiong Yin , Hao Cheng , Siming Fu , Yuhao Zhang , Wanggui He

Pathology image classification plays a crucial role in accurate medical diagnosis and treatment planning. Training high-performance models for this task typically requires large-scale annotated datasets, which are both expensive and…

计算机视觉与模式识别 · 计算机科学 2025-07-01 Lanfeng Zhong , Xin Liao , Shichuan Zhang , Shaoting Zhang , Guotai Wang

Despite the promises of data-driven artificial intelligence (AI), little is known about how we can bridge the gulf between traditional physician-driven diagnosis and a plausible future of medicine automated by AI. Specifically, how can we…

人机交互 · 计算机科学 2021-02-12 Hongyan Gu , Jingbin Huang , Lauren Hung , Xiang 'Anthony' Chen

LLM-based agents have demonstrated strong potential for autonomous machine learning, yet their applicability to health data remains limited. Existing systems often struggle to generalize across heterogeneous health data modalities, rely…

人工智能 · 计算机科学 2026-02-03 Tong Xia , Weibin Li , Gang Liu , Yong Li

As advances in large language models (LLMs) and multimodal techniques continue to mature, the development of general-purpose multimodal large language models (MLLMs) has surged, offering significant applications in interpreting natural…

计算机视觉与模式识别 · 计算机科学 2024-02-20 Yuxuan Sun , Chenglu Zhu , Sunyi Zheng , Kai Zhang , Lin Sun , Zhongyi Shui , Yunlong Zhang , Honglin Li , Lin Yang

Artificial Intelligence (AI) brings advancements to support pathologists in navigating high-resolution tumor images to search for pathology patterns of interest. However, existing AI-assisted tools have not realized this promised potential…

Large Language Model (LLM)-based agents have demonstrated strong capabilities across a wide range of tasks, and their application in the medical domain holds particular promise due to the demand for high generalizability and reliance on…

人工智能 · 计算机科学 2025-08-18 Yangyang Zhuang , Wenjia Jiang , Jiayu Zhang , Ze Yang , Joey Tianyi Zhou , Chi Zhang