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Background. Alzheimer's disease and related dementia (ADRD) are characterized by multiple and progressive anatomo clinical changes. Yet, modeling changes over disease course from cohort data is challenging as the usual timescales are…

统计方法学 · 统计学 2024-07-17 Jérémie Lespinasse , Carole Dufouil , Cécile Proust-Lima , the MEMENTO study group

Due to the sensitive nature of diabetes-related data, preventing them from being shared between studies, progress in the field of glucose prediction is hard to assess. To address this issue, we present GLYFE (GLYcemia Forecasting…

信号处理 · 电气工程与系统科学 2020-06-30 Maxime De Bois , Mehdi Ammi , Mounîm A. El Yacoubi

Large language and music models are increasingly used for constrained generation: rhyming lines, fixed meter, inpainting or infilling, positional endings, and other global form requirements. These systems often perform strikingly well, but…

人工智能 · 计算机科学 2026-04-10 Francois Pachet , Pierre Roy

Causal inference, estimating causal effects from observational data, is a fundamental tool in many disciplines. Of particular importance across a variety of domains is the continuous treatment setting, where the variable of intervention has…

机器学习 · 计算机科学 2026-05-15 Christopher Stith , Medha Barath , Vahid Balazadeh , Jesse C. Cresswell , Rahul G. Krishnan

Controllable trajectory generation guided by high-level semantic decisions, termed meta-actions, is crucial for autonomous driving systems. A significant limitation of existing frameworks is their reliance on invariant meta-actions assigned…

机器人学 · 计算机科学 2025-05-30 Jianbo Zhao , Taiyu Ban , Xiyang Wang , Qibin Zhou , Hangning Zhou , Zhihao Liu , Mu Yang , Lei Liu , Bin Li

In biomedical research, repeated measurements within each subject are often processed to remove artifacts and unwanted sources of variation. The resulting data are used to construct derived outcomes that act as proxies for scientific…

统计方法学 · 统计学 2026-02-03 Zihang Wang , Razieh Nabi , Benjamin B. Risk

Most tabular-data generators match marginal statistics yet ignore causal structure, leading downstream models to learn spurious or unfair patterns. We present TabSCM, a mixed-type generator that preserves those causal dependencies. Starting…

机器学习 · 计算机科学 2026-04-27 Sven Jacob , Bardh Prenkaj , Weijia Shao , Gjergji Kasneci

The field of hypothesis generation promises to reduce costs in neuroscience by narrowing the range of interventional studies needed to study various phenomena. Existing machine learning methods can generate scientific hypotheses from…

机器学习 · 计算机科学 2025-07-04 Zachary C. Brown , David Carlson

Protein sequence generation via stochastic attention produces plausible family members from small alignments without training, but treats all stored sequences equally and cannot direct generation toward a functional subset of interest. We…

机器学习 · 计算机科学 2026-03-23 Jeffrey D. Varner

Event temporal graphs have been shown as convenient and effective representations of complex temporal relations between events in text. Recent studies, which employ pre-trained language models to auto-regressively generate linearised graphs…

计算与语言 · 计算机科学 2024-04-03 Xingwei Tan , Yuxiang Zhou , Gabriele Pergola , Yulan He

From medical diagnosis to autonomous vehicles, critical applications rely on the integration of multiple heterogeneous data modalities. Multimodal Variational Autoencoders offer versatile and scalable methods for generating unobserved…

机器学习 · 计算机科学 2025-02-07 Agathe Senellart , Stéphanie Allassonnière

Historical prescriptions and selected candidate drugs relevant to the current visit serve as important references for medication recommendation. However, in the absence of explicit intrinsic principles for semantic composition, existing…

计算工程、金融与科学 · 计算机科学 2026-01-28 Yanda Wang , Weitong Chen , Chao Tan , Ian Nabney , Lin Yue , Genlin Ji

We consider causal inference in dynamic settings where treatment is assigned by thresholding a state variable that can change over time. There is a large literature on regression-discontinuity methods building on the fact that, in the…

统计方法学 · 统计学 2026-05-25 Aditya Ghosh , Stefan Wager

Autoregressive sequence Generation models have achieved state-of-the-art performance in areas like machine translation and image captioning. These models are autoregressive in that they generate each word by conditioning on previously…

计算与语言 · 计算机科学 2021-01-26 Longteng Guo , Jing Liu , Xinxin Zhu , Hanqing Lu

Postprandial glucose collected through continuous glucose monitoring (CGM) provides critical information for assessing metabolic capacity and guiding dietary recommendations. Traditional approaches summarize these data into scalar measures,…

定量方法 · 定量生物学 2026-04-03 Marcos Matabuena , Joe Sartini , Francisco Gude

Decision-making related to health is complex. Machine learning (ML) and patient generated data can identify patterns and insights at the individual level, where human cognition falls short, but not all ML-generated information is of equal…

应用统计 · 统计学 2021-01-15 Elliot G Mitchell , Esteban G Tabak , Matthew E Levine , Lena Mamykina , David J Albers

Medication recommendation systems play a crucial role in assisting clinicians with personalized treatment decisions. While existing approaches have made significant progress in learning medication representations, they suffer from two…

机器学习 · 计算机科学 2025-11-19 Kelin Ren , Chan-Yang Ju , Dong-Ho Lee

Confounding bias and selection bias bring two significant challenges to the validity of conclusions drawn from applied causal inference. The latter can stem from informative missingness, such as in cases of attrition. We introduce the…

统计方法学 · 统计学 2025-03-25 Johan de Aguas , Johan Pensar , Tomás Varnet Pérez , Guido Biele

Medical artificial intelligence (AI) systems, particularly multimodal vision-language models (VLM), often exhibit intersectional biases where models are systematically less confident in diagnosing marginalised patient subgroups. Such bias…

计算机视觉与模式识别 · 计算机科学 2025-12-25 Yupeng Zhang , Adam G. Dunn , Usman Naseem , Jinman Kim

We study causal discovery from a single observed sequence of discrete events generated by a stochastic process, as encountered in vehicle logs, manufacturing systems, or patient trajectories. This regime is particularly challenging due to…

机器学习 · 计算机科学 2026-03-18 Hugo Math , Rainer Lienhart