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Medication adherence is a well-known problem for pharmaceutical treatment of chronic diseases. Understanding how nonadherence affects treatment efficacy is made difficult by the ethics of clinical trials that force patients to skip doses of…

定量方法 · 定量生物学 2021-12-30 Elijah D Counterman , Sean D Lawley

We propose a simple data augmentation protocol aimed at providing a compositional inductive bias in conditional and unconditional sequence models. Under this protocol, synthetic training examples are constructed by taking real training…

计算与语言 · 计算机科学 2020-05-20 Jacob Andreas

The classical multilevel model fails to capture the proximity effect in epidemiological studies, where subjects are nested within geographical units. Multilevel Conditional Autoregressive models are alternatives to help explain the spatial…

统计方法学 · 统计学 2021-11-24 Dany Djeudeu , Susanne Moebus , Katja Ickstadt

Mixed-effect models are very popular for analyzing data with a hierarchical structure, e.g. repeated observations within subjects in a longitudinal design, patients nested within centers in a multicenter design. However, recently, due to…

统计方法学 · 统计学 2019-05-09 Abhik Ghosh , Magne Thoresen

In this work, we address the task of unconditional head motion generation to animate still human faces in a low-dimensional semantic space from a single reference pose. Different from traditional audio-conditioned talking head generation…

计算机视觉与模式识别 · 计算机科学 2023-04-18 Louis Airale , Xavier Alameda-Pineda , Stéphane Lathuilière , Dominique Vaufreydaz

Three-dimensional (3D) medical images, such as Computed Tomography (CT) and Magnetic Resonance Imaging (MRI), are essential for clinical applications. However, the need for diverse and comprehensive representations is particularly…

计算机视觉与模式识别 · 计算机科学 2025-05-26 Siwen Wang , Churan Wang , Fei Gao , Lixian Su , Fandong Zhang , Yizhou Wang , Yizhou Yu

Asynchronous stochastic gradient descent (ASGD) is a standard way to exploit heterogeneous compute resources in distributed learning: instead of forcing fast workers to wait for slow ones, the server updates the model whenever a gradient…

机器学习 · 计算机科学 2026-05-14 Ammar Mahran , Artavazd Maranjyan , Peter Richtárik

Some patients benefit from a treatment while others may do so less or do not benefit at all. We have previously developed a two-stage network meta-regression prediction model that synthesized randomized trials and evaluates how treatment…

Automatic International Classification of Diseases (ICD) coding aims to assign multiple ICD codes to a medical note with an average of 3,000+ tokens. This task is challenging due to the high-dimensional space of multi-label assignment…

计算与语言 · 计算机科学 2022-11-30 Zhichao Yang , Sunjae Kwon , Zonghai Yao , Hong Yu

The traditional model specification of stepped-wedge cluster-randomized trials assumes a homogeneous treatment effect across time while adjusting for fixed-time effects. However, when treatment effects vary over time, the constant effect…

统计方法学 · 统计学 2025-04-22 Zhe Chen , Wei Wang , Yingying Lu , Scott D. Halpern , Katherine R. Courtright , Fan Li , Michael O. Harhay

Objective: In randomized clinical trials, prediction models can be used to explore the relationships between patients' variables (e.g., clinical, pathological, or lifestyle variables, and also biomarker or genomic data) and treatment effect…

定量方法 · 定量生物学 2026-02-03 Elvire Roblin , Paul-Henry Cournède , Stefan Michiels

Many financial time series have varying structures at different quantile levels, and also exhibit the phenomenon of conditional heteroscedasticity at the same time. In the meanwhile, it is still lack of a time series model to accommodate…

统计理论 · 数学 2020-12-29 Qianqian Zhu , Guodong Li

Diffusion language models enable any-order generation and bidirectional conditioning, offering appealing flexibility for tasks such as infilling, rewriting, and self-correction. However, their formulation-predicting one part of a sequence…

计算与语言 · 计算机科学 2026-01-21 Tianqi Du , Lizhe Fang , Weijie Yang , Chenheng Zhang , Zeming Wei , Yifei Wang , Yisen Wang

Autoregressive models have emerged as a powerful framework for modeling exchangeable sequences - i.i.d. observations when conditioned on some latent factor - enabling direct modeling of uncertainty from missing data (rather than a latent).…

机器学习 · 计算机科学 2025-03-04 Daksh Mittal , Ang Li , Tzu-Ching Yen , Daniel Guetta , Hongseok Namkoong

Normalizing flows are a powerful class of generative models for continuous random variables, showing both strong model flexibility and the potential for non-autoregressive generation. These benefits are also desired when modeling discrete…

机器学习 · 统计学 2019-06-06 Zachary M. Ziegler , Alexander M. Rush

This paper investigates new ways of estimating and identifying causal, noncausal, and mixed causal-noncausal autoregressive models driven by a non-Gaussian error sequence. We do not assume any parametric distribution function for the…

计量经济学 · 经济学 2022-11-28 Alain Hecq , Daniel Velasquez-Gaviria

Accurate forecasting of blood glucose from CGM is essential for preventing dysglycemic events, thus enabling proactive diabetes management. However, current forecasting models treat blood glucose readings captured using CGMs as a numerical…

机器学习 · 计算机科学 2026-01-12 Shovito Barua Soumma , Hassan Ghasemzadeh

Clinical diagnosis, which aims to assign diagnosis codes for a patient based on the clinical note, plays an essential role in clinical decision-making. Considering that manual diagnosis could be error-prone and time-consuming, many…

计算与语言 · 计算机科学 2021-01-28 Yichao Du , Pengfei Luo , Xudong Hong , Tong Xu , Zhe Zhang , Chao Ren , Yi Zheng , Enhong Chen

Time series generation is a crucial research topic in the area of decision-making systems, which can be particularly important in domains like autonomous driving, healthcare, and, notably, robotics. Recent approaches focus on learning in…

机器学习 · 计算机科学 2024-09-16 Jian Qian , Bingyu Xie , Biao Wan , Minhao Li , Miao Sun , Patrick Yin Chiang

In-context learning has recently been linked to implicit gradient descent in linear self-attention models, suggesting that context can induce a forward-pass update. Retrieval-augmented generation (RAG) also relies on context, but retrieved…

计算与语言 · 计算机科学 2026-05-27 Mingchen Li , Jiatan Huang , Chuxu Zhang , Liang Zhao , Hong Yu
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