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Trans-membrane gradients and fluxes of cations (H+, Na+, K+, etc.) were deemed to be the rationale of electrical activities of aerobic cells/organelles, as per classical perceptions. Murburn concept (an umbrella of theorization based in…

神经元与认知 · 定量生物学 2026-04-29 Kelath Murali Manoj , Nagamani Sukumar

Physics perfectly describes neuronal operation, provided that we take into account that biology uses slow, positively charged ions rather than electrons as charge carriers and remove untested ad hoc hypotheses that contradict science's…

生物物理 · 物理学 2026-04-13 János Végh

The Hodgkin-Huxley (HH) model is the currently accepted formalism of neuronal excitability. However, the HH model does not capture a number of biophysical behaviors associated with action potentials or propagating nerve impulses. Physical…

神经元与认知 · 定量生物学 2015-06-17 Jerel Mueller , William J. Tyler

This chapter revisits the concept of excitability, a basic system property of neurons. The focus is on excitable systems regarded as behaviors rather than dynamical systems. By this we mean open systems modulated by specific interconnection…

神经元与认知 · 定量生物学 2017-04-18 Rodolphe Sepulchre , Guillaume Drion , Alessio Franci

We present a microscopic approach for the coupling of cortical activity, as resulting from proper dipole currents of pyramidal neurons, to the electromagnetic field in extracellular fluid in presence of diffusion and Ohmic conduction.…

神经元与认知 · 定量生物学 2013-10-08 Peter beim Graben , Serafim Rodrigues

The generation of action potential brings into play specific mechanosensory stimuli manifest in the variation of membrane capacitance, resulting from the selective membrane permeability to ions exchanges and testifying to the central role…

神经元与认知 · 定量生物学 2021-02-23 Alain M. Dikande

The Thermodynamic Formalism provides a rigorous mathematical framework to study quantitative and qualitative aspects of dynamical systems. At its core there is a variational principle corresponding, in its simplest form, to the Maximum…

神经元与认知 · 定量生物学 2020-12-30 Rodrigo Cofré , Cesar Maldonado , Bruno Cessac

Active inference is a normative framework for explaining behaviour under the free energy principle -- a theory of self-organisation originating in neuroscience. It specifies neuronal dynamics for state-estimation in terms of a descent on…

神经元与认知 · 定量生物学 2021-10-26 Lancelot Da Costa , Thomas Parr , Biswa Sengupta , Karl Friston

The neural mechanism of memory has a very close relation with the problem of representation in artificial intelligence. In this paper a computational model was proposed to simulate the network of neurons in brain and how they process…

神经元与认知 · 定量生物学 2020-12-02 Hui Wei

Neuronal excitability is the phenomena that describes action potential generation due to a stimulus input. Commonly, neuronal excitability is divided into two classes: Type I and Type II, both having different properties that affect…

神经元与认知 · 定量生物学 2020-11-03 Jantine A. C. Broek , Guillaume Drion

Most models of neurons incorporate a capacitor to account for the marked capacitive behavior exhibited by the cell membrane. However, such capacitance is widely considered constant, thereby neglecting the possible effects of time-dependent…

神经元与认知 · 定量生物学 2025-12-29 Matías Courdurier , Leonel E. Medina , Esteban Paduro

Activity in neocortex exhibits a range of behaviors, from irregular to temporally precise, and from weakly to strongly correlated. So far there has been no single theoretical framework that could explain all these behaviors, leaving open…

神经元与认知 · 定量生物学 2015-11-03 Alexander Lerchner , Peter E. Latham

Neural electromagnetic (EM) signals recorded non-invasively from individual human subjects vary in complexity and magnitude. Nonetheless, variation in neural activity has been difficult to quantify and interpret, due to complex, broad-band…

Our understanding of neural computation is founded on the assumption that neurons fire in response to a linear summation of inputs. Yet experiments demonstrate that some neurons are capable of complex functions that require interactions…

生物物理 · 物理学 2026-03-23 Christopher W. Lynn

This paper attempts to review our studies on the propagation of signals in nerves over the past decade. The need for interdisciplinary studies is stressed that helps to understand the physical mechanisms of coupling the electrical,…

生物物理 · 物理学 2024-12-24 Jüri Engelbrecht , Kert Tamm , Tanel Peets

This paper presents an overview of some techniques and concepts coming from dynamical system theory and used for the analysis of dynamical neural networks models. In a first section, we describe the dynamics of the neuron, starting from the…

适应与自组织系统 · 物理学 2011-11-09 B. Cessac , M. Samuelides

The animal nervous system offers a model of computation combining digital reliability and analog efficiency. Understanding how this sweet spot can be realized is a core question of neuromorphic engineering. To this aim, this paper explores…

系统与控制 · 电气工程与系统科学 2026-02-19 Michelangelo Bin , Alessandro Cecconi , Lorenzo Marconi

Signals recorded from neurons with extracellular planar sensors have a wide range of waveforms and amplitudes. This variety is a result of different physical conditions affecting the ion currents through a cellular membrane. The…

Recent work emphasizes that the maximum entropy principle provides a bridge between statistical mechanics models for collective behavior in neural networks and experiments on networks of real neurons. Most of this work has focused on…

神经元与认知 · 定量生物学 2015-06-05 Gasper Tkacik , Olivier Marre , Thierry Mora , Dario Amodei , Michael J. Berry , William Bialek

This paper describes the outlines of a research program for understanding the cognitive-emotional brain, with an emphasis on the issue of dynamics: How can we study, characterize, and understand the neural underpinnings of…

神经元与认知 · 定量生物学 2019-02-04 Luiz Pessoa
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