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Agentic retrieval-augmented reasoning pipelines are increasingly used to structure how large language models (LLMs) incorporate external evidence in clinical decision support. These systems iteratively retrieve curated domain knowledge and…

Large language models (LLMs) have shown promise in medical domains, but their ability to handle specialized neurological reasoning requires systematic evaluation. We developed a comprehensive benchmark using 305 questions from Israeli Board…

信息检索 · 计算机科学 2025-08-21 Moran Sorka , Alon Gorenshtein , Dvir Aran , Shahar Shelly

The application of Large Language Models (LLMs) in healthcare is expanding rapidly, with one potential use case being the translation of formal medical reports into patient-legible equivalents. Currently, LLM outputs often need to be edited…

多智能体系统 · 计算机科学 2024-08-06 Malavikha Sudarshan , Sophie Shih , Estella Yee , Alina Yang , John Zou , Cathy Chen , Quan Zhou , Leon Chen , Chinmay Singhal , George Shih

Large Language Models (LLMs) exhibit high reasoning capacity in medical question-answering, but their tendency to produce hallucinations and outdated knowledge poses critical risks in healthcare fields. While Retrieval-Augmented Generation…

计算与语言 · 计算机科学 2026-03-25 Wenhao Wu , Zhentao Tang , Yafu Li , Shixiong Kai , Mingxuan Yuan , Chunlin Chen , Zhi Wang

Large language model (LLM) agents extend generative models with reasoning, tool use, and persistent memory, thereby enabling the automation of complex tasks. In healthcare, such systems could support documentation, care coordination, and…

人工智能 · 计算机科学 2026-03-24 Wenxian Yang , Hanzheng Qiu , Bangqun Zhang , Chengquan Li , Zhiyong Huang , Xiaobin Feng , Rongshan Yu , Jiahong Dong

While large language models are capable diagnostic tools, the impact of multi-agent topology on diagnostic accuracy remains underexplored. This study evaluates four agent topologies, Control (single agent), Hierarchical, Adversarial, and…

多智能体系统 · 计算机科学 2026-03-10 Ahmed Almasoud

The integration of Large Language Models (LLMs) into healthcare is constrained by knowledge limitations, hallucinations, and a disconnect from Evidence-Based Medicine (EBM). While Retrieval-Augmented Generation (RAG) offers a solution,…

计算与语言 · 计算机科学 2026-02-03 Qiaoyu Zheng , Yuze Sun , Chaoyi Wu , Weike Zhao , Pengcheng Qiu , Yongguo Yu , Kun Sun , Jian Zhang , Yanfeng Wang , Ya Zhang , Weidi Xie

Evaluating large language models (LLM) in clinical scenarios is crucial to assessing their potential clinical utility. Existing benchmarks rely heavily on static question-answering, which does not accurately depict the complex, sequential…

人机交互 · 计算机科学 2025-05-27 Samuel Schmidgall , Rojin Ziaei , Carl Harris , Eduardo Reis , Jeffrey Jopling , Michael Moor

In modern medicine, clinical diagnosis relies on the comprehensive analysis of primarily textual and visual data, drawing on medical expertise to ensure systematic and rigorous reasoning. Recent advances in large Vision-Language Models…

人工智能 · 计算机科学 2025-07-03 Ziyue Wang , Junde Wu , Linghan Cai , Chang Han Low , Xihong Yang , Qiaxuan Li , Yueming Jin

Unstructured notes within the electronic health record (EHR) contain rich clinical information vital for cancer treatment decision making and research, yet reliably extracting structured oncology data remains challenging due to extensive…

Multimodal clinical reasoning in the field of gastrointestinal (GI) oncology necessitates the integrated interpretation of endoscopic imagery, radiological data, and biochemical markers. Despite the evident potential exhibited by Multimodal…

With the increasing demand for step-wise, cross-modal, and knowledge-grounded reasoning, multimodal large language models (MLLMs) are evolving beyond the traditional fixed retrieve-then-generate paradigm toward more sophisticated agentic…

人工智能 · 计算机科学 2026-03-03 Xuying Ning , Dongqi Fu , Tianxin Wei , Mengting Ai , Jiaru Zou , Ting-Wei Li , Hanghang Tong , Yada Zhu , Hendrik Hamann , Jingrui He

We present M-Reason, a demonstration system for transparent, agent-based reasoning and evidence integration in the biomedical domain, with a focus on cancer research. M-Reason leverages recent advances in large language models (LLMs) and…

人工智能 · 计算机科学 2025-10-08 Oskar Wysocki , Magdalena Wysocka , Mauricio Jacobo , Harriet Unsworth , André Freitas

Accurate interpretation of clinical narratives is critical for patient care, but the complexity of these notes makes automation challenging. While Large Language Models (LLMs) show promise, single-model approaches can lack the robustness…

人工智能 · 计算机科学 2025-09-01 Yeawon Lee , Xiaoyang Wang , Christopher C. Yang

Rare diseases affect over 300 million individuals worldwide, yet timely and accurate diagnosis remains an urgent challenge. Patients often endure a prolonged diagnostic odyssey exceeding five years, marked by repeated referrals,…

计算与语言 · 计算机科学 2026-02-17 Weike Zhao , Chaoyi Wu , Yanjie Fan , Xiaoman Zhang , Pengcheng Qiu , Yuze Sun , Xiao Zhou , Yanfeng Wang , Xin Sun , Ya Zhang , Yongguo Yu , Kun Sun , Weidi Xie

Clinical decision-making requires nuanced reasoning over heterogeneous evidence and traceable justifications. While recent LLM multi-agent systems (MAS) show promise, they largely optimise for outcome accuracy while overlooking…

人工智能 · 计算机科学 2026-02-17 Chaeeun Lee , T. Michael Yates , Pasquale Minervini , T. Ian Simpson

An effective healthcare agent must be able to recall and reason over a patient's longitudinal medical history. However, the absence of datasets with realistic long-term dialogue timelines limits systematic evaluation. Real clinical text is…

计算与语言 · 计算机科学 2026-05-20 Hebin Hu , Renke Dai , Ah-Hwee Tan , Yilin Kang

Interleaved text-and-image generation represents a significant frontier for Multimodal Large Language Models (MLLMs), offering a more intuitive way to convey complex information. Current paradigms rely on either image generation or…

人工智能 · 计算机科学 2026-04-01 Yinuo Liu , Zi Qian , Heng Zhou , Jiahao Zhang , Yajie Zhang , Zhihang Li , Mengyu Zhou , Erchao Zhao , Xiaoxi Jiang , Guanjun Jiang

We introduce Agentic Reasoning, a framework that enhances large language model (LLM) reasoning by integrating external tool-using agents. Agentic Reasoning dynamically leverages web search, code execution, and structured memory to address…

人工智能 · 计算机科学 2025-07-16 Junde Wu , Jiayuan Zhu , Yuyuan Liu , Min Xu , Yueming Jin

Large language models are increasingly being assembled into medical multi-agent systems that emulate multidisciplinary consultation through specialist roles, peer review and consensus formation. In clinical decision support, however,…

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