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Alzheimer's disease (AD) progresses from asymptomatic changes to clinical symptoms, emphasizing the importance of early detection for proper treatment. Functional magnetic resonance imaging (fMRI), particularly dynamic functional network…

计算工程、金融与科学 · 计算机科学 2024-08-02 Yuxiang Wei , Anees Abrol , James Lah , Deqiang Qiu , Vince D. Calhoun

Disease progression modeling (DPM) using longitudinal data is a challenging task in machine learning for healthcare that can provide clinicians with better tools for diagnosis and monitoring of disease. Existing DPM algorithms neglect…

计算机视觉与模式识别 · 计算机科学 2018-08-17 Mostafa Mehdipour Ghazi , Mads Nielsen , Akshay Pai , M. Jorge Cardoso , Marc Modat , Sebastien Ourselin , Lauge Sørensen

Multi-modal biological, imaging, and neuropsychological markers have demonstrated promising performance for distinguishing Alzheimer's disease (AD) patients from cognitively normal elders. However, it remains difficult to early predict when…

计算机视觉与模式识别 · 计算机科学 2019-01-08 Hongming Li , Yong Fan

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline and memory loss. Early detection of AD is crucial for effective intervention and treatment. In this paper, we propose a novel approach…

音频与语音处理 · 电气工程与系统科学 2025-04-29 Yu Pu , Wei-Qiang Zhang

Recently, temporal action detection (TAD) has seen significant performance improvement with end-to-end training. However, due to the memory bottleneck, only models with limited scales and limited data volumes can afford end-to-end training,…

计算机视觉与模式识别 · 计算机科学 2024-04-23 Shuming Liu , Chen-Lin Zhang , Chen Zhao , Bernard Ghanem

Deep learning has shown significant potential in diagnosing neurodegenerative diseases from MRI data. However, most existing methods rely heavily on large volumes of labeled data and often yield representations that lack interpretability.…

计算机视觉与模式识别 · 计算机科学 2025-09-10 Fangqi Cheng , Yingying Zhao , Xiaochen Yang

Modeling continuous-time physiological processes that manifest a patient's evolving clinical states is a key step in approaching many problems in healthcare. In this paper, we develop the Hidden Absorbing Semi-Markov Model (HASMM): a…

人工智能 · 计算机科学 2016-12-28 Ahmed M. Alaa , Mihaela van der Schaar

Understanding the interactions between biomarkers among brain regions during neurodegenerative disease is essential for unravelling the mechanisms underlying disease progression. For example, pathophysiological models of Alzheimer's Disease…

Functional data is a powerful tool for capturing and analyzing complex patterns and relationships in a variety of fields, allowing for more precise modeling, visualization, and decision-making. For example, in healthcare, functional data…

统计方法学 · 统计学 2023-04-26 Xiyuan Gao , Jiayi Wang , Guanyu Hu , Jianguo Sun

We propose a novel tensor-on-tensor modeling framework that flexibly models nonlinear voxel-level relationships using Gaussian process (GP) priors, while incorporating the spatial structure of the output tensor through low-rank tensor-based…

统计方法学 · 统计学 2026-04-10 Yajie Liu , Hengrui Luo , Suprateek Kundu

Audio-visual emotion recognition (AVER) methods typically fuse utterance-level features, and even frame-level attention models seldom address the frame-rate mismatch across modalities. In this paper, we propose a Transformer-based framework…

多媒体 · 计算机科学 2026-03-13 Inyong Koo , yeeun Seong , Minseok Son , Jaehyuk Jang , Changick Kim

Individualized Alzheimer's disease (AD) progression prediction requires models that use irregular visits, account for censoring, avoid diagnostic leakage, and provide calibrated horizon risks. We propose PROgression-aware MultI-horizon…

机器学习 · 计算机科学 2026-05-01 Qing Lyu , Jeremy Hudson , Mohammad Kawas , Yuming Jiang , Chenyu You , Christopher T Whitlow

This paper aims to study the prediction of the bank stability index based on the Time Series Transformer model. The bank stability index is an important indicator to measure the health status and risk resistance of financial institutions.…

风险管理 · 定量金融 2024-12-06 Wenying Sun , Zhen Xu , Wenqing Zhang , Kunyuan Ma , You Wu , Mengfang Sun

Address-Event-Representation (AER) is a spike-routing protocol that allows the scaling of neuromorphic and spiking neural network (SNN) architectures to a size that is comparable to that of digital neural network architectures. However, in…

神经与进化计算 · 计算机科学 2023-04-28 Madhuvanthi Srivatsav R , Shantanu Chakrabartty , Chetan Singh Thakur

Alzheimer's is a brain disease that gets worse over time and affects memory, thinking, and behavior. Alzheimer's disease (AD) can be treated and managed if it is diagnosed early, which can slow the progression of symptoms and improve…

图像与视频处理 · 电气工程与系统科学 2024-01-09 Taymaz Akan , Sait Alp , Mohammad A. N Bhuiyanb

Bearing fault detection is a critical task in predictive maintenance, where accurate and timely fault identification can prevent costly downtime and equipment damage. Traditional attention mechanisms in Transformer neural networks often…

机器学习 · 计算机科学 2024-12-17 Marzieh Mirzaeibonehkhater , Mohammad Ali Labbaf-Khaniki , Mohammad Manthouri

Alzheimer's disease (AD) is a progressive neurological disorder, meaning that the symptoms develop gradually throughout the years. It is also the main cause of dementia, which affects memory, thinking skills, and mental abilities. Nowadays,…

计算与语言 · 计算机科学 2022-11-09 Loukas Ilias , Dimitris Askounis , John Psarras

A number of life threatening neuro-degenerative disorders had degraded the quality of life for the older generation in particular. Dementia is one such symptom which may lead to a severe condition called Alzheimer's disease if not detected…

神经与进化计算 · 计算机科学 2024-02-01 Anuvab Sen , Udayon Sen , Subhabrata Roy

Characterizing a preclinical stage of Alzheimer's Disease (AD) via single imaging is difficult as its early symptoms are quite subtle. Therefore, many neuroimaging studies are curated with various imaging modalities, e.g., MRI and PET,…

图像与视频处理 · 电气工程与系统科学 2025-03-06 Seunghun Baek , Jaeyoon Sim , Mustafa Dere , Minjeong Kim , Guorong Wu , Won Hwa Kim

Generative AI framework-based modeling and prediction of longitudinal human brain images offer an efficient mechanism to track neurodegenerative progression, essential for the assessment of diseases like Alzheimer's. Among the existing…

计算机视觉与模式识别 · 计算机科学 2026-03-03 Ayantika Das , Keerthi Ram , Mohanasankar Sivaprakasam